Browse > Article
http://dx.doi.org/10.5536/KJPS.2008.35.3.283

Effect of Dietary Siberian Ginseng and Eucommia on Broiler Performance, Serum Biochemical Profiles and Telomere Length  

Sohn, S.H. (Department of Animal Science & Biotechnology, Jinju National University)
Jang, I.S. (Department of Animal Science & Biotechnology, Jinju National University)
Moon, Y.S. (Department of Animal Science & Biotechnology, Jinju National University)
Kim, Y.J. (Department of Animal Science & Biotechnology, Jinju National University)
Lee, S.H. (Department of Animal Science & Biotechnology, Jinju National University)
Ko, Y.H. (Department of Animal Science & Biotechnology, Jinju National University)
Kang, S.Y. (Department of Animal Science & Biotechnology, Jinju National University)
Kang, H.K. (Department of Animal Science & Biotechnology, Jinju National University)
Publication Information
Korean Journal of Poultry Science / v.35, no.3, 2008 , pp. 283-290 More about this Journal
Abstract
The Siberian ginseng and Eucommia are a kind of medicinal plant with powerful anti-oxidant activity. An experiment was conducted to investigate the effect of Siberian ginseng leaf and Eucommia leaf at level of 0.5% and 1% per feed in Ross commercial broiler for 4 to 35 days of age on performance, organ weight, blood biochemical profiles and telomere quantity. Chickens consuming diets containing 1% Siberian ginseng had higher feed conversion ratio than the other treated chicken during experimental period whereas no significant differences were detected in body weight, weight gain and feed intake. The weight of bursa of fabricius was significantly increased in chickens with dietary supplementation compared with chickens fed control but this was not seen in liver, spleen and thymus. In blood biochemical profiles, chickens with dietary supplementation had higher concentration than chickens fed control in triglyceride, cholesterol and glucose. The concentration of aspartate aminotransferase, alanine aminotransferase, albumin and total protein, however, was not significantly different between dietary supplemented chickens and control chickens. The relative amount of telomeric DNA of lymphocytes in chickens with dietary supplementation was significantly higher than that of control chickens but the difference was not found in liver, heart and testis tissues. In conclusion, dietary supplementation of Siberian ginseng and Eucommia in broiler improved immune activity and telomere length without decreasing chicken growth performance.
Keywords
Siberian ginseng; Eucommia; anti-oxidant; telomere; growth performance; broiler;
Citations & Related Records
연도 인용수 순위
  • Reference
1 Benetos A, Okuda K, Lajemi M, Kimura M, Thomas F, Skurnick J, Labat C, Bean K, Aviv A 2001 Telomere length as an indicator of biological aging: the gender effect and relation with pulse pressure and pulse wave velocity. Hypertension 37(2):381-385   DOI   ScienceOn
2 Hernandez F, Madrid J, Garcia V, Orengo J, Megias MD 2004 Influence of two plant extracts on broilers performance, digestibility, and digestive organ size. Poult Sci 83(2):169-174   DOI
3 Jeanclos E, Schork NJ, Kyvik KO, Kimura M, Skurnick JH, Aviv A 2000 Telomere length inversely correlates with pulse pressure and is highly familial. Hypertension 36(2):195-200   DOI   ScienceOn
4 Lee SE, Shin HT, Hwang HJ, Kim JH 2003 Antioxidant activity of extracts from Alpinia katsumadai seed. Phytother Res 7(9):1041-1047
5 Saretzki G, von Zglinicki T 1999 Replicative senescence as a model of aging: the role of oxidative stress and telomere shortening. Z Gerontol Geriatr 32(2):69-75   DOI
6 Sohn SH, Multani AS, Gugnani PK, Pathak S 2002 Telomere erosion-induced mitotic catastrophe in continuously grown Chinese hamster Don cells. Exptl Cell Res 279(2):271-276   DOI   ScienceOn
7 Uchida Y 1991 Growth-inhibitory factor. No To Shinkei 43(12): 1114-1120
8 Cottliar AS, Slavutsky IR 2001 Telomeres and telomerase activity: their role in aging and in neoplastic development. Medicina 61:335-342
9 Rama Rao SV, Raju MV, Panda AK, Reddy MR 2006 Sunflower seed meal as a substitute for soybean meal in commercial broiler chicken diets. Br Poult Sci 47(5):592-598   DOI   ScienceOn
10 Okuda K, Bardeguez A, Gardner JP, Rodriguez P, Ganesh V, Kimura M, Skurnick J, Awad G, Aviv A 2002 Telomere length in the newborn. Pediatr Res 52(3):377-381   DOI   ScienceOn
11 Goni I, Brenes A, Centeno C, Viveros A, Saura-Calixto F, Rebole A, Arija I, Estevez R 2007 Effect of dietary grape pomace and vitamin E on growth performance, nutrient digestibility, and susceptibility to meat lipid oxidation in chickens. Poult Sci 86(3):508-516   DOI
12 Ribatti D, Crivellato E, Vacca A 2006 The contribution of Bruce Glick to the definition of the role played by the bursa of Fabricius in the development of the B cell lineage. Clin Exp Immunol 145(1):1-4   DOI   ScienceOn
13 Greider CW, Blackburn EH 1985 Identification of a specific telomere terminal transferase activity in Tetrahymena extracts. Cell 43:405-413   DOI   ScienceOn
14 Hsieh CL, Yen GC 2000 Antioxidant actions of du-zhong (Eucommia ulmoides Oliv.) toward oxidative damage in biomolecules. Life Sci 66(15):1387-1400   DOI   ScienceOn
15 Frenck RW Jr, Blackburn EH, Shannon KM 1998 The rate of telomere sequence loss in human leukocytes varies with age. Proc Natl Acad Sci 95(10):5607-10
16 Haendeler J, Hoffmann J, Diehl JF, Vasa M, Spyridopoulos I, Zeiher AM, Dimmeler S 2004 Antioxidants inhibit nuclear export of telomerase reverse transcriptase and delay replicative senescence of endothelial cells. Circ Res 94(6):768-775   DOI   ScienceOn
17 Rebole A, Rodriguez ML, Ortiz LT, Alzueta C, Centeno C, Viveros A, Brenes A, Arija I 2006 Effect of dietary high-oleic acid sunflower seed, palm oil and vitamin E supplementation on broiler performance, fatty acid composition and oxidation susceptibility of meat. Br Poult Sci 47(5):581-591   DOI   ScienceOn
18 Galvin K, Morrissey PA, Buckley DJ 1997 Influence of dietary vitamin E and oxidised sunflower oil on the storage stability of cooked chicken muscle. Br Poult Sci 38(5):499-504   DOI   ScienceOn
19 Shi Y, Wang W, Mo J, Du L, Yao S, Tang W 2003 Interactions of growth inhibitory factor with hydroxyl and superoxide radicals. Biometals 16(3):383-389   DOI   ScienceOn
20 Xu D, Neville R, Finkel T 2000 Homocysteine accelerates endothelial cell senescence. FEBS Lett 470(1):20-24   DOI   ScienceOn
21 O'Neill LM, Galvin K, Morrissey PA, Buckley DJ 1998 Comparison of effects of dietary olive oil, tallow and vitamin E on the quality of broiler meat and meat products. Br Poult Sci 39(3):365-371   DOI   ScienceOn
22 Lopez-Bote CJ, Gray JI, Gomaa EA, Flegal CJ 1998 Effect of dietary administration of oil extracts from rosemary and sage on lipid oxidation in broiler meat. Br Poult Sci 39(2):235-240   DOI
23 Brenes A, Viveros A, Goñi I, Centeno C, Sáyago-Ayerdy SG, Arija I, Saura-Calixto F 2008 Effect of grape pomace concentrate and vitamin E on digestibility of polyphenols and antioxidant activity in chickens. Poult Sci 87(2):307-316   DOI   ScienceOn
24 Kurz DJ, Decary S, Hong Y, Trivier E, Akhmedov A, Erusalimsky JD 2004 Chronic oxidative stress compromises telomere integrity and accelerates the onset of senescence in human endothelial cells. J Cell Sci 117:2417-2426   DOI   ScienceOn
25 Ross Broiler Management Manual 2002 Aviagen Incorporated, Huntsville, Alabama
26 von Zglinicki T 2000 Role of oxidative stress in telomere length regulation and replicative senescence. Ann N Y Acad Sci 908:99-110
27 Amella M, Bronner C, Briancon F, Haag M, Anton R, Landry Y 1985 Inhibition of mast cell histamine release by flavonoids and biflavonoids. Planta Med 1:16-20
28 Bar-Or D, Thomas GW, Rael LT, Lau EP, Winkler JV 2001 Asp-Ala-His-Lys (DAHK) inhibits copper-induced oxidative DNA double strand breaks and telomere shortening. Biochem Biophys Res Commun 282(1):356-360   DOI   ScienceOn
29 Ahmed A, Tollefsbol T 2001 Telomeres and telomerase: basic science implications for aging. J Am Geriatr Soc 49(8): 1105-1109   DOI   ScienceOn