Isolation of Acetylcholinesterase Inhibitors from the Flowers of Chrysanthemum indicum Linne |
Lim, Soon-Sung
(Regional Innovation Center, Hallym University)
Han, Sag-Myung (Department of Food Science and Nutrition, The Korean Institute of Nutrition, Hallym University) Kim, Sun-Young (Department of Food Science and Nutrition, The Korean Institute of Nutrition, Hallym University) Bae, Young-Soo (Department of Wood Science and Engineering, Kangwon National University) Kang, Il-Jun (Department of Food Science and Nutrition, The Korean Institute of Nutrition, Hallym University) |
1 | Yoshikawa M, Morikawa T, Murakami T, Toguchida I, Harima S, Matsuda H. Medicinal flowers. I. Aldose reductase inhibitors and three new eudesmane-type sesquiterpenes, kikkanols A, B, and C, from the flowers of Chrysanthemum indicum L. Chem. Pharm. Bull. 47: 340-345 (1999) DOI ScienceOn |
2 | Michael WW, Huang KC. The dried flower and petal of Chrysanthemum indicum L., C boreale Mak., and C.lavandulaefolium (Fisch.) Mak. p. 83. In: The Pharmacology of Chinese Herbs: 2nded. CRC Press, lnc., Boca Raton, FL, USA (1997) |
3 | Sugimoto H, Tsuchiya Y, Sugumi H, Higurashi K, Karibe N, Iimura Y, Sasaki A, Kawakami Y, Nakamura T, Araki S. Novel piperidine derivatives. Synthesis and anti-acetylcholinesterase activity of 1benzyl-4-[2-(N-benzoylamino)ethyl]piperidine derivatives. J. Med. Chem. 33: 1880-1887 (1990) DOI |
4 | Jann MW. Rivastigmine, a new-generation cholinesterase inhibitor for the treatment of Alzheimer's disease. Pharmacotherapy 20: 1-12 (2000) DOI ScienceOn |
5 | Hana SY, Sweeneyb JE, Bachmanb ES, Schweigera EJ, Forlonic G, Coyleb JT, Davis BM, Joullie MM. Chemical and pharmacological characterization of galanthamine, an acetylcholinesterase inhibitor, and its derivatives. A potential application in Alzheimer's disease. Eur. J. Med. Chem. 27: 673-687 (1992) DOI ScienceOn |
6 | Loy C, Schneider L. Galantamine for Alzheimer's disease. Cochrane DB. Syst. Rev. 18: CD001747 (2004) |
7 | Cha JD, Jeong MR, Lee YE. Induction of apoptosis in human oral epidermoid carcinoma cells by essential oil of Chrysanthemum boreale Makino. Food Sci. BioTechnol. 14: 350-354 (2005) |
8 | Yoshikawa M, Morikawa T, Toguchida I, Harima S, Matsuda H. Medicinal flowers. II. Inhibitors of nitric oxide production and absolute stereostructures of five new germacrane-type sesquiterpenes, kikkanols D, D monoacetate, E, F, and F monoacetate from the flowers of Chrysanthemum indicum L. Chem. Pharm. Bull. 48: 651-656 (2000) DOI ScienceOn |
9 | Woo ER, Piao MS. Antioxidative constituents from Lycopus lucidus. Arch. Pharm. Res. 27: 173-176 (2004) DOI ScienceOn |
10 | Tabarrini O, Cecchetti V, Temperini A, Filipponi E, Lamperti MG, Fravolini A. Velnacrine thia-analogues as potential agents for treating Alzheimer's disease. Bioorgan. Med. Chem. 9: 2921-2928 (2001) DOI ScienceOn |
11 | Fredj G, Dietlin F, Barbier G, Jasmin C, Bonhomme L, Esctein S, Misset JL, Meyer P, Kalifa D, Beugre T. Comparison oftacrine hepatotoxicity in patients with Alzheimer disease or AIDS. Therapie 47: 245-247 (1992) |
12 | Duh P, Tu Y, Yen G. Antioxidant activity of water extract of Harng Jyur (Chrysanthemum morifolium Ramat) Lebensm. -Wiss. Technol. 32: 269-277 (1999) DOI ScienceOn |
13 | Ellman GL, Lourtney DK, Andres V, Gmelin G A new and rapid colorimetric determination of acetylcholinesterase activity. Biochem. Pharmacol. 7: 88-95 (1961) DOI ScienceOn |
14 | Winkler J, Thai LJ, Gage FH, Fisher LJ. Cholinergic strategies for Alzheimer's disease. J. Mol. Med. 76: 555-567 (1998) DOI |
15 | Nunomura A, Perry G, Aliev G, Hirai K, Takeda A, Balraj EK, Jones PK, Ghanbari H, Wataya T, Shimohama S, Chiba S, Atwood CS, Petersen RB, Smith MA. Oxidative damage is the earliest event in Alzheimer disease. J. Neuropath. Exp. Neur. 60: 759-767 (2001) DOI |
16 | Bores GM, Huger FP, Petko W, Mutlib AE, Camacho F, Rush DK, Selk DE, Wolf V, Kosley RW Jr, Davis L, Vargas HM. Pharmacological evaluation of novel Alzheimer's disease therapeutics: acetylcholinesterase inhibitors related to galanthamine. J. Pharmacol. Exp. Ther. 277: 728-738 (1996) |
17 | Zhu S, Yang Y, Yu H, Ying Y, Zou G. Chemical composition and antimicrobial activity of the essential oils of Chrysanthemum indicum. J. Ethnopharmacol. 96: 151-158 (2005) DOI ScienceOn |
18 | Matsuda H, Morikawa T, Toguchida I, Harima S, Yoshikawa M. Medicinal flowers. VI. Absolute stereostructures of two new flavanone glycosides and a phenylbutanoid glycoside from the flowers of Chrysanthemum indicum L.: their inhibitory activities for rat lens aldose reductase. Chem. Pharm. Bull. 50: 972-975 (2002) DOI ScienceOn |
19 | Ingkaninan K, Temkitthawon P, Chuenchom K, Yuyaem T, Thongnoi W. Screening for acetylcholinesterase inhibitory activity in plants used in Thai traditional rejuvenating and neurotonic remedies. J. Ethnopharmacol. 89: 261-264 (2003) DOI ScienceOn |
20 | Lane RM, Potkin SG, Enz A. Targeting acetylcholinesterase and butyrylcholinesterase in dementia. Int. J. Neuropsychoph. 9: 101-124 (2006) |
21 | Chatterjee A, Sarkar S, Saha SK. Acacetin 7-O--D-galactopyranoside from Chrysanthemum indicum. Phytochemistry 20: 1760-1761 (1981) DOI ScienceOn |
22 | Lleo A, Greenberg SM, Growdon JH. Current pharmacotherapy for Alzheimer's disease. Annu. Rev. Med. 57: 513-533 (2006) DOI ScienceOn |
23 | Wang ZG, Ren AN, Xu L, Sun XJ, Hua XB. The experimental study on the immunological and anti-inflammatory activities of Chrysanthemum indicum. Chinese J. Trad. Med. Sci. Technol. 2: 92-93 (2000) |
24 | Kim S, Cho J, Wee J, Jang M, Kim C, Rim Y, Shin S, Ma S, Moon J, Park K. Isolation and characterization of antioxidative compounds from the aerial parts of Angelica keiskei. Food Sci. Biotechnol. 14: 58-63 (2005) |
25 | Quinn DM. Acetylcholinesterase - enzyme structure, reaction dynamics, and virtual transition states. Chem. Rev. 87: 955-979 (1987) DOI |
26 | Jeon JR, Park JR. Effects of Chrysanthemum boreale M. water extract on serum liver enzyme activities and Kupffer cells of carbon tetrachloride-induced rats. Food Sci. Biotechnol. 14: 290-296 (2005) |
27 | Wagner H, Aurnhammer G, Horammer L, Farkas L. Investigations on the glycosides of acacetin. II. Note on the identity of acaciin from Robinia pseudoacacia L. with Iinarin from Linaria vulgaris P. Mill. Chem. Ber. 102: 1445-1446 (1969) DOI ScienceOn |
28 | Duh P. Antioxidant activity of water extract of four Harng Jyur (Chrysanthemum morifolium Rarnat) varieties in soybean oil emulsion. Food Chem. 66: 471-476 (1999) DOI ScienceOn |