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Effects of Cheonggukjang on Immune Responses and Gastrointestinal Functions in Rats  

Lee, Chang-Hyun (Department of Anatomy, College of Oriental Medicine, Woosuk University)
Yang, Eun-In (Faculty of Biotechnology (Food Science & Technology Major), Chonbuk National University)
Song, Geun-Seoup (Department of Food Engineering, Iksan National College)
Chai, Ok-Hee (Department of Anatomy, Chonbuk National University Medical School)
Kim, Young-Soo (Faculty of Biotechnology (Food Science & Technology Major), Chonbuk National University)
Publication Information
Food Science and Biotechnology / v.15, no.1, 2006 , pp. 19-23 More about this Journal
Abstract
Effects of cheonggukjang on immunohistochemical reactions in gastrointestinal (GI) tract of rats were investigated. $CD4^+/CD8^+$ immunoreactive cells of cheonggukjang-fed diet groups were more strongly stained in lamina propria of mucosa and submucosa than those of basal diet group. Universal nitric oxide synthase immunoreactive density in colon was mildly stained in surface epithelium and mucous secretory gland, and strongly stained in submucosa and myenteric plexus in muscle layers of all cheonggukjang-fed diet groups. Protein kinase C-${\alpha}$ immunoreactive cells in colons of 15 and 25% cheonggukjang-fed diet groups were more strongly stained in mucosa, submucosa, and muscle layers than those of basal diet group. These results indicate mucosal immune activity, gastrointestinal motility, blood circulation, and physiological activities of enteroendocrine cells in GI tract could be increased with cheonggukjang intake.
Keywords
cheonggukjang; gastrointestinal tract; immunohistochemical density; universal nitric oxide synthase; protein kinase C-${\alpha}$;
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