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http://dx.doi.org/10.3839/jabc.2020.058

Physiological activities of leaf extract of Lonicera morrowii A.Gray, a plant native to Ulleungdo  

Lee, Eun-Ho (School of Food science & Biotechnology, Kyungpook National University)
Park, Hye-Jin (School of Food science & Biotechnology, Kyungpook National University)
Hong, Eun-Jin (School of Food science & Biotechnology, Kyungpook National University)
Akhmadjon, Sultanov (School of Food science & Biotechnology, Kyungpook National University)
Kim, Byung-Oh (School of Food science & Biotechnology, Kyungpook National University)
Jung, Hee-Young (School of Applied Biosciences, Kyungpook National University)
Kang, In-Kyu (Department of Horticultural Science, Kyungpook National University)
Cho, Young-Je (School of Food science & Biotechnology, Kyungpook National University)
Publication Information
Journal of Applied Biological Chemistry / v.63, no.4, 2020 , pp. 443-449 More about this Journal
Abstract
This study was performed to investigate total phenolic contents, anti-oxidant, biological disease-related enzyme inhibitory, and anti-microbial effects of extracts of Lonicera morrowii leaves prepared with water and 40% ethanol. Anti-oxidative activities of the extracts increased in a dose-dependent manner and were very high even at low phenolic concentration. At phenolic concentrations ranging between 50 and 200 ㎍/mL, the water and ethanol extracts inhibited 39.34-76.35 and 47.53-99.83% of xanthine oxidase activity, 30.21-79.06, and 59.40-87.14% of angiotensin converting enzyme activity, and 59.81-80.35 and 36.06-63.58% of α-glucosidase activity, respectively. All inhibitory effect were increased in a dose-dependent manner. In the paper disc agar diffusion assay against seven microbes, L. morrowii extracts had anti-bacteria activities against Helicobacter pylori, Propionibacterium acne but no effect against other bacteria. These results indicate that the extracts from L. morrowii leaves have the possibility to be developed as a physiologically functional source for prevention of adult diseases.
Keywords
Anti-microbial; Anti-oxidant; Biological activity; Extracts; Lonicera morrowii A.Gray; Phenolic compounds;
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