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http://dx.doi.org/10.3839/jabc.2017.027

Comparison of proximate compositions, antioxidant, and antiproliferative activities between blueberry and Sageretia thea (Osbeck) M.C.Johnst fruit produced in Jeju Island  

Ko, Gyeong-A (Faculty of Biotechnology, College of Applied Life Sciences, SARI, Jeju National University)
Koh, So Yae (Faculty of Advanced Convergence Technology and Science, Jeju National University)
Ryu, Ji-yeon (School of Biomaterials Sciences and Technology, College of Applied Life Sciences, SARI, Jeju National University)
Cho, Somi Kim (Faculty of Biotechnology, College of Applied Life Sciences, SARI, Jeju National University)
Publication Information
Journal of Applied Biological Chemistry / v.60, no.2, 2017 , pp. 161-171 More about this Journal
Abstract
This study was aimed to evaluate and compare the proximate composition, antioxidant and antiproliferative activities of Sageretia thea (Osbeck) M.C.Johnst (S. thea) fruit and blueberry. The calorific value, crude protein, crude fat, crude ash, and carbohydrate were higher in S. thea fruit than in blueberry. S. thea fruit and blueberry have different profile of free sugars, in which amounts of fructose, glucose, and maltose were much higher in S. thea fruit than in blueberry. The methanol extracts of S. thea fruit contain higher amounts of total polyphenol and anthocyanin compared to those of blueberry extracts. In additions, 2,2-diphenyl-1-picrylhydrazyl (DPPH), alkyl, and 2,2'-azinobis(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) radical scavenging activities are greater in S. thea fruit extracts. Ethyl acetate fractions and n-butanol fractions of S. thea fruit and blueberry show the most potent scavenging activity in DPPH-, alkyl-, and ABTS-radical scavenging assay. The ethyl acetate fractions of S. thea fruit and blueberry are the richest fraction in polyphenol contents while the n-butanol fractions of those are the highest fraction in anthocyanin contents. Furthermore, both S. thea fruit and blueberry extracts protect human dermal fibroblast cells against a $H_2O_2$-induced oxidative stress. The antiproliferative activities of n-hexane and chloroform fraction from S. thea fruit and blueberry were observed in AGS human gastric cancer and MDA-MB-231 human breast cancer cells. Therefore, our results suggest for the first time that the antioxidant and antiproliferative activities of S. thea fruit is comparable to that of blueberry and the nutritional value of the former is even superior to that of the latter.
Keywords
Antioxidant; Antiproliferative; Blueberry; Proximate compositions; Sageretia thea (Osbeck) M.C.Johnst;
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1 Adams LS, Phung S, Yee N, Seeram NP, Li L, Chen S (2010) Blueberry phytochemicals inhibit growth and metastatic potential of MDA-MB-231 breast cancer cells through modulation of the phosphatidylinositol 3-kinase pathway. Cancer Res 70: 3594-3605   DOI
2 Amarowicz R, Pegg RB, Rahimi-Moghaddam P, Barl B, Weil JA (2004) Free-radical scavenging capacity and antioxidant activity of selected plant species from the Canadian prairies. Food Chem 84: 551-562   DOI
3 Ames BN, Shigenaga MK, Hagen TM (1993) Oxidants, antioxidants, and the degenerative diseases of aging. Proc Nati Acad Sci USA 90: 7915-7922   DOI
4 An YH, Lee IS, Kim HS (2015) Quality Characteristics of Sikhye made with Berries. Korean J Food Cook Sci 27: 803-814
5 Awika JM, Rooney LW, Wu X, Prior RL, Cisneros-Zevallos L (2003) Screening methods to measure antioxidant activity of sorghum (Sorghum bicolor) and sorghum products. J Agric Food Chem 51: 6657-6662   DOI
6 Bin Sayeed MS, Ameen SS (2015) Beta-sitosterol: a promising but orphan nutraceutical to fight against cancer. Nutr Cancer 67: 1216-1222   DOI
7 Bridle P, Timberlake C (1997) Anthocyanins as natural food colours-selected aspects. Food Chem 58: 103-109   DOI
8 Carmichael J, DeGraff WG, Gazdar AF, Minna JD, Mitchell JB (1987) Evaluation of a tetrazolium-based semiautomated colorimetric assay: assessment of chemosensitivity testing. Cancer Res 47: 936-942
9 Cechovska L, Cejpek K, Konecny M, Velisek J (2011) On the role of 2,3-dihydro-3,5-dihydroxy-6-methyl-(4H)-pyran-4-one in antioxidant capacity of prunes, Eur Food Res Technol 233:367-376   DOI
10 Cheung LM, Cheung PCK, Ooi VEC (2003) Antioxidant activity and total phenolics of edible mushroom extracts. Food Chem 81: 249-255   DOI
11 Cho WJ, Song BS, Lee JY, Kim JK, Kim JH, Yoon YH, Choi JI, Kim GS, Lee JW (2010) Composition Analysis of Various Blueberries Produced in Korea and Manufacture of Blueberry Jam by Response Surface Methodology J Korean Soc Food Sci Nutr
12 Chung HJ (2015) Comparative study of antioxidant activity of imported tropical and subtropical fruits. Korean J Food Preserv 22: 577-584   DOI
13 Chung SK, Chen CYO, Blumberg JB (2009) Flavonoid-rich fraction from Sageretia theezans leaves scavenges reactive oxygen radical species and increases the resistance of low-density lipoprotein to oxidation. J Med Food 12: 1310-1315   DOI
14 Chung SK, Kim YC, Takaya Y, Terashima K, Niwa M (2004) Novel flavonol glycoside, 7-O-methyl mearnsitrin, from Sageretia theezans and its antioxidant effect. J Agric Food Chem 52: 4664-4668   DOI
15 Cikman O, Soylemez O, Ozkan OF, Kiraz HA, Sayar I, Ademoglu S, Taysi S, Karaayvaz M (2015) Antioxidant Activity of Syringic Acid Prevents Oxidative Stress in l-arginine-Induced Acute Pancreatitis: An Experimental Study on Rats. Int Surg 100: 891-896   DOI
16 de Souza VR, Pereira PA, da Silva TL, de Oliveira Lima LC, Pio R, Queiroz F (2014) Determination of the bioactive compounds, antioxidant activity and chemical composition of Brazilian blackberry, red raspberry, strawberry, blueberry and sweet cherry fruits. Food Chem 156: 362-368 doi:10.1016/j.foodchem.2014.01.125   DOI
17 Floegel A, Kim DO, Chung SJ, Koo SI, Chun OK (2011) Comparison of ABTS/DPPH assays to measure antioxidant capacity in popular antioxidant-rich US foods. J Food Compos Anal 24: 1043-1048   DOI
18 Horwitz W, Chichilo P, Reynolds H (1970) Official methods of analysis of the Association of Official Analytical Chemists Official methods of analysis of the Association of Official Analytical Chemists
19 Food K, Association D (2005) Food standards codex Korean Foods Industry Association Seoul, Korea: 367-368
20 Francis FJ (1989) Food colorants: anthocyanins. Crit Rev Food Sci Nutr 28: 273-314   DOI
21 Hyon JS, Kang SM, Han SW, Kang MC, Oh MC, Oh CK, Kim DW, Jeon YJ, Kim SH (2009) Flavonoid Component Changes and Antioxidant Activities of Fermented Citrus grandis Osbeck Peel. Journal of food science and nutrition 38: 1310-1316
22 Hyun TK, Song SC, Song CK, Kim JS (2015) Nutritional and nutraceutical characteristics of Sageretia theezans fruit. J Food Drug Analy 23: 742-749   DOI
23 Jang HH, Nam SY, Kim MJ, Kim JB, Kim HR, Lee YM (2014) Antioxidant Activity and Protective Effects of Anthocyanins-Rich Fraction from Korean Purple Sweet Potato Variety, "Shinjami" against Oxidative Stress in HepG2 Cell. Korean J Food & Nutr 27: 1090-1095   DOI
24 Jang HL, Yoon KY (2012) Biological Activities and Total Phenolic Content of Ethanol Extracts of White and Flesh-colored Solanum tuberosum L. Potatoes. J Korean Soc Food Sci Nutr 41: 1035-1040   DOI
25 Jubri Z, Rahim NBA, Aan GJ (2013) Manuka honey protects middle-aged rats from oxidative damage. Clinics (Sao Paulo) 68: 1446-1454   DOI
26 Kim J, Lee J, Park S (2011) Seed atlas of Korean plants. Academy Publishing, Seoul (in Korean)
27 Lee Y, Lee JH, Kim SD, Shang MS, Jo IS, Kim SJ, Hwang KT, Jo HB, Kim JH (2015) Chemical Composition, Functional Constituents, and Antioxidant Activities of Berry Fruits Produced in Korea. J Korean Soc Food Sci Nutr 44: 1295-1303   DOI
28 Kumar S, Prahalathan P, Raja B (2011) Antihypertensive and antioxidant potential of vanillic acid, a phenolic compound in L-NAME-induced hypertensive rats: a dose-dependence study. Redox Rep 16: 208-215   DOI
29 Hiramoto K, Johkoh H, Sako K, Kikugawa K (1993) DNA breaking activity of the carbon-centered radical generated from 2, 2-azobis (2-amidinopropane) hydrochloride (AAPH). Free Radic Res Commun 19: 323-332   DOI
30 Lee SO, Lee HJ, Yu MH, Im HG, Lee IS (2005) Total polyphenol contents and antioxidant activities of methanol extracts from vegetables produced in Ullung island. Korean J Food Sci and Technol 37: 233-240
31 Lemanska K, Szymusiak H, Tyrakowska B, Zielinski R, Soffers AE, Rietjens IM (2001) The influence of pH on antioxidant properties and the mechanism of antioxidant action of hydroxyflavones. Free Radic Biol Med 31: 869-881   DOI
32 Loo AY, Jain K, Darah I (2008) Antioxidant activity of compounds isolated from the pyroligneous acid, Rhizophora apiculata. Food Chem 107: 1151-1160   DOI
33 Martineau LC, Couture A, Spoor D, Benhaddou-Andaloussi A, Harris C, Meddah B, Leduc C, Burt A, Vuong T, Mai Le P, Prentki M, Bennett SA, Arnason JT, Haddad PS (2006) Anti-diabetic properties of the Canadian lowbush blueberry Vaccinium angustifolium Ait. Phytomedicine 13: 612-623   DOI
34 Naczk M, Shahidi F (2003) Phenolic compounds in plant foods: chemistry and health benefits. Nutraceuticals and Food 8: 200-218
35 Papandreou MA, Dimakopoulou A, Linardaki ZI, Cordopatis P, Klimis-Zacas D, Margarity M, Lamari FN (2009) Effect of a polyphenol-rich wild blueberry extract on cognitive performance of mice, brain antioxidant markers and acetylcholinesterase activity. Behav Brain Res 198: 352-358   DOI
36 Nanjo F, Goto K, Seto R, Suzuki M, Sakai M, Hara Y (1996) Scavenging effects of tea catechins and their derivatives on 1, 1-diphenyl-2-picrylhydrazyl radical. Free Radic Biol Med 21: 895-902   DOI
37 Ozturk Sarikaya SB (2015) Acethylcholinesterase inhibitory potential and antioxidant properties of pyrogallol. J Enzyme Inhib Med Chem 30: 761-766   DOI
38 Pan MH, Chang YH, Badmaev V, Nagabhushanam K, Ho CT (2007) Pterostilbene induces apoptosis and cell cycle arrest in human gastric carcinoma cells. J Agric Food Chem 55: 7777-7785   DOI
39 Park JC, Hur JM, Park JG, Hatano T, Yoshida T, Miyashiro H, Min BS, Hattori M (2002) Inhibitory effects of Korean medicinal plants and camelliatannin H from Camellia japonica on human immunodeficiency virus type 1 protease. Phytother Res 16: 422-426   DOI
40 Re R, Pellegrini N, Proteggente A, Pannala A, Yang M, Rice-Evans C (1999) Antioxidant activity applying an improved ABTS radical cation decolorization assay. Free Radic Biol Med 26: 1231-1237   DOI
41 Sato M, Ramarathnam N, Suzuki Y, Ohkubo T, Takeuchi M, Ochi H (1996) Varietal differences in the phenolic content and superoxide radical scavenging potential of wines from different sources. J Agric Food Chem 44: 37-41   DOI
42 Seeram NP (2008) Berry fruits: compositional elements, biochemical activities, and the impact of their intake on human health, performance, and disease. J Agric Food Chem 56: 627-629   DOI
43 Song SC, Song CK, Kim JS (2014) Vegetation and Habitat Environment of Sageretia thea in Jeju Island. Korean J Med Crop Sci 22: 301-305   DOI
44 Seeram NP, Adams LS, Zhang Y, Lee R, Sand D, Scheuller HS, Heber D (2006) Blackberry, black raspberry, blueberry, cranberry, red raspberry, and strawberry extracts inhibit growth and stimulate apoptosis of human cancer cells in vitro. J Agric Food Chem 54: 9329-9339   DOI
45 Sellappan S, Akoh CC, Krewer G (2002) Phenolic compounds and antioxidant capacity of Georgia-grown blueberries and blackberries. J Agric Food Chem 50: 2432-2438   DOI
46 Seol GH, Kang P, Lee HS, Seol GH (2016) Antioxidant activity of linalool in patients with carpal tunnel syndrome. BMC Neurol. doi: 10.1186/s12883-016-0541-3
47 Velika B, Kron I (2012) Antioxidant properties of benzoic acid derivatives against superoxide radical. Free Radicals and Antioxidants 2: 62-67
48 Wang M, Li J, Rangarajan M, Shao Y, LaVoie EJ, Huang TC, Ho CT (1998) Antioxidative phenolic compounds from sage (Salvia officinalis). J Agric Food Chem 46: 4869-4873   DOI
49 Wang SY, Jiao H (2000) Scavenging capacity of berry crops on superoxide radicals, hydrogen peroxide, hydroxyl radicals, and singlet oxygen. J Agric Food Chem 48: 5677-5684   DOI
50 Wang Z, Ma L, Zhang X, Xu L, Cao J, Jiang W (2015) The effect of exogenous salicylic acid on antioxidant activity, bioactive compounds and antioxidant system in apricot fruit. Scientia Hortic 181: 113-120   DOI
51 Yang DP, Ji HF, Tang GY, Ren W, Zhang HY (2007) How many drugs are catecholics Molecules 12: 878-884   DOI
52 Abdel-Aal E-SM, Hucl P (2003) Composition and stability of anthocyanins in blue-grained wheat. J Agric food Chem 51: 2174-2180   DOI
53 Yu X, Zhao M, Liu F, Zeng S, Hu J (2013) Identification of 2,3-dihydro-3,5-dihydroxy-6-methyl-4H-pyran-4-one as a strong antioxidant in glucose-histidine Maillard reaction products. Food Res Int 51: 397-403   DOI