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http://dx.doi.org/10.3839/jabc.2009.009

Antimicrobial Activity and Cell Cytotoxicity of Korean Plum-yem Extract  

Cho, Chul-Hee (Department of Food and Biotechnology, Center for Food Function and Safety and Basic Science Institute, Hoseo University)
Yoo, Gui-Jae (Department of Food and Biotechnology, Center for Food Function and Safety and Basic Science Institute, Hoseo University)
Kim, So-Young (Department of Food and Biotechnology, Center for Food Function and Safety and Basic Science Institute, Hoseo University)
Lee, Gun-Soon (Departmant of Living Sciences, Korea National Agricultural College)
Kim, Jin-Hyun (Department of Chemical Engineering, Kongju National University)
Hyun, Jung-Oh (Department of Forest Sciences, Seoul National University)
Chae, Hee-Jeong (Department of Food and Biotechnology, Center for Food Function and Safety and Basic Science Institute, Hoseo University)
Publication Information
Journal of Applied Biological Chemistry / v.52, no.2, 2009 , pp. 45-50 More about this Journal
Abstract
Antimicrobial activity and cell cytotoxicity of Korean Plum-yem (Cephalotaxus koreana) extract were evaluated for the development of a functional biomaterial. And the chemical compositions of Korean Plum-yem extract (KPE) were analyzed. KPE showed high antimicrobial activities against various microorganisms including gram-positive bacteria, gram-negative bacteria, yeasts and molds. KPE showed cytotoxic activity dose-dependently against blood cancer cell line K562. Additionally, the KPE showed no significant adverse effect in hemolysis and no mutagenicity. It was suggested that KPE could be used as a functional biomaterial for functional food and cosmetics
Keywords
antimicrobial activity; cell cytotoxicity; Cephalotaxus koreana; Korean Plum-yem; toxicity evaluation;
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Times Cited By KSCI : 5  (Citation Analysis)
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