Exercise training and selenium or a combined treatment ameliorates aberrant expression of glucose and lactate metabolic proteins in skeletal muscle in a rodent model of diabetes
![]() |
Kim, Seung-Suk
(Exercise Biochemistry Laboratory, Korea National Sport University)
Koo, Jung-Hoon (Exercise Biochemistry Laboratory, Korea National Sport University) Kwon, In-Su (Exercise Biochemistry Laboratory, Korea National Sport University) Oh, Yoo-Sung (Department of Sport Informatics, University of Seoul) Lee, Sun-Jang (Department of Physical Education, Keimyung University) Kim, Eung-Joon (Exercise Biochemistry Laboratory, Korea National Sport University) Kim, Won-Kyu (Department of Anatomy and Cell Biology, Collage of Medicine, Hanyang University) Lee, Jin (Department of Anatomy and Cell Biology, Collage of Medicine, Hanyang University) Cho, Joon-Yong (Exercise Biochemistry Laboratory, Korea National Sport University) |
1 | Tan MH, Bonen A, Garner JB, Belcastro AN. Physical training in diabetic rats: effect on glucose tolerance and serum lipids. J Appl Physiol 1982;52:1514-8. DOI |
2 | Tancrede G, Rousseau-Migneron S, Nadeau A. Beneficial effects of physical training in rats with a mild streptozotocin-induced diabetes mellitus. Diabetes 1982;31:406-9. DOI ScienceOn |
3 | Hayashi T, Hirshman MF, Kurth EJ, Winder WW, Goodyear LJ. Evidence for 5' AMP-activated protein kinase mediation of the effect of muscle contraction on glucose transport. Diabetes 1998;47:1369-73. DOI ScienceOn |
4 | Hardie DG, Sakamoto K. AMPK: a key sensor of fuel and energy status in skeletal muscle. Physiology (Bethesda) 2006;21:48-60. DOI ScienceOn |
5 | Py G, Eydoux N, Perez-Martin A, Raynaud E, Brun JF, Prefaut C, Mercier J. Streptozotocin-induced diabetes decreases rat sarcolemmal lactate transport. Metabolism 2001;50:418-24. DOI ScienceOn |
6 | McCullagh KJ, Poole RC, Halestrap AP, O'Brien M, Bonen A. Role of the lactate transporter (MCT1) in skeletal muscles. Am J Physiol 1996;271:E143-50. |
7 | Hughes GM, Szegletes T, Nemcsok J. A comparison of blood composition in the common carp (Cyprinus carpio L.) using samples obtained from caudal vessels and dorsal aorta cannulae. Acta Biol Hung 1997;48:145-55. |
8 | Bonen A, Tonouchi M, Miskovic D, Heddle C, Heikkila JJ, Halestrap AP. Isoform-specific regulation of the lactate transporters MCT1 and MCT4 by contractile activity. Am J Physiol Endocrinol Metab 2000;279:E1131-8. DOI |
9 | Juel C, Halestrap AP. Lactate transport in skeletal muscle - role and regulation of the monocarboxylate transporter. J Physiol 1999;517:633-42. DOI ScienceOn |
10 | Calle MC, Fernandez ML. Effects of resistance training on the inflammatory response. Nutr Res Pract 2010;4:259-69. DOI |
11 | MacFarquhar JK, Broussard DL, Melstrom P, Hutchinson R, Wolkin A, Martin C, Burk RF, Dunn JR, Green AL, Hammond R, Schaffner W, Jones TF. Acute selenium toxicity associated with a dietary supplement. Arch Intern Med 2010;170:256-61. DOI ScienceOn |
12 | Bo S, Lezo A, Menato G, Gallo ML, Bardelli C, Signorile A, Berutti C, Massobrio M, Pagano GF. Gestational hyperglycemia, zinc, selenium, and antioxidant vitamins. Nutrition 2005;21:186-91. DOI ScienceOn |
13 | Ostenson CG, Efendic S. Islet gene expression and function in type 2 diabetes; studies in the Goto-Kakizaki rat and humans. Diabetes Obes Metab 2007;9 Suppl 2:180-6. DOI ScienceOn |
14 | American Physiological Society Operational Guide Revision. Guiding Principles for the Care and Use of Animal in the Recommendations for the Declaration of Helsinki 1964. The American Physiological Society; 2002. p.297-306. |
15 | Hwang D, Seo S, Kim Y, Kim C, Shim S, Jee S, Lee S, Jang M, Kim M, Yim S, Lee SK, Kang B, Jang I, Cho J. Selenium acts as an insulin-like molecule for the down-regulation of diabetic symptoms via endoplasmic reticulum stress and insulin signalling proteins in diabetes-induced non-obese diabetic mice. J Biosci 2007;32:723-35. DOI ScienceOn |
16 | Hamamoto Y, Tsuura Y, Fujimoto S, Nagata M, Takeda T, Mukai E, Fujita J, Yamada Y, Seino Y. Recovery of function and mass of endogenous beta-cells in streptozotocin-induced diabetic rats treated with islet transplantation. Biochem Biophys Res Commun 2001;287:104-9. DOI ScienceOn |
17 | Lowry OH, Passonneau JV. A flexible system of enzymatic analysis. New York: Academic Press; 1972. p.147-217. |
18 | Terada S, Goto M, Kato M, Kawanaka K, Shimokawa T, Tabata I. Effects of low-intensity prolonged exercise on PGC-1 mRNA expression in rat epitrochlearis muscle. Biochem Biophys Res Commun 2002;296:350-4. DOI ScienceOn |
19 | Terada S, Tabata I. Effects of acute bouts of running and swimming exercise on PGC-1alpha protein expression in rat epitrochlearis and soleus muscle. Am J Physiol Endocrinol Metab 2004;286:E208-16. DOI |
20 | Ayaz M, Ozdemir S, Ugur M, Vassort G, Turan B. Effects of selenium on altered mechanical and electrical cardiac activities of diabetic rat. Arch Biochem Biophys 2004;426:83-90. DOI ScienceOn |
21 | Furnsinn C, Englisch R, Ebner K, Nowotny P, Vogl C, Waldhausl W. Insulin-like vs. non-insulin-like stimulation of glucose metabolism by vanadium, tungsten, and selenium compounds in rat muscle. Life Sci 1996;59:1989-2000. DOI ScienceOn |
22 | Song XM, Kawano Y, Krook A, Ryder JW, Efendic S, Roth RA, Wallberg-Henriksson H, Zierath JR. Muscle fiber type-specific defects in insulin signal transduction to glucose transport in diabetic GK rats. Diabetes 1999;48:664-70. DOI ScienceOn |
23 | Enoki T, Yoshida Y, Hatta H, Bonen A. Exercise training alleviates MCT1 and MCT4 reductions in heart and skeletal muscles of STZ-induced diabetic rats. J Appl Physiol 2003;94:2433-8. DOI |
24 | Metz L, Vermaelen M, Lambert K, Broca C, Sirvent P, Raynaud E, Mercier J. Endurance training increases lactate transport in male Zucker fa/fa rats. Biochem Biophys Res Commun 2005;331:1338-45. DOI ScienceOn |
25 | Sriwijitkamol A, Coletta DK, Wajcberg E, Balbontin GB, Reyna SM, Barrientes J, Eagan PA, Jenkinson CP, Cersosimo E, DeFronzo RA, Sakamoto K, Musi N. Effect of acute exercise on AMPK signaling in skeletal muscle of subjects with type 2 diabetes: a time-course and dose-response study. Diabetes 2007;56:836-48. DOI ScienceOn |
26 | Muller AS, Most E, Pallauf J. Effects of a supranutritional dose of selenate compared with selenite on insulin sensitivity in type II diabetic dbdb mice. J Anim Physiol Anim Nutr (Berl) 2005;89:94-104. DOI ScienceOn |
27 | Ostergard T, Nyholm B, Hansen TK, Rasmussen LM, Ingerslev J, Sorensen KE, Botker HE, Saltin B, Schmitz O. Endothelial function and biochemical vascular markers in first-degree relatives of type 2 diabetic patients: the effect of exercise training. Metabolism 2006;55:1508-15. DOI |
28 | Pilegaard H, Saltin B, Neufer PD. Exercise induces transient transcriptional activation of the PGC-1alpha gene in human skeletal muscle. J Physiol 2003;546:851-8. DOI ScienceOn |
29 | Arteel GE, Sies H. The biochemistry of selenium and the glutathione system. Environ Toxicol Pharmacol 2001;10:153-8. DOI ScienceOn |
30 | Mckenzie RC, Arthur JR, Miller SM, Rafferty TS, Beckett GJ. Selenium and immune function. In: Calder PC, Field CJ, Gill HS, editors. Nutrition and immune function. Wallingford: CABI Publishing; 2002. p.229-50. |
31 | Faure P, Ramon O, Favier A, Halimi S. Selenium supplementation decreases nuclear factor-kappa B activity in peripheral blood mononuclear cells from type 2 diabetic patients. Eur J Clin Invest 2004;34:475-81. DOI ScienceOn |
32 | Diplock AT. Antioxidant nutrients and disease prevention: an overview. Am J Clin Nutr 1991;53(1 Suppl):189S-193S. |
33 | Brown JB, Pedula K, Barzilay J, Herson MK, Latare P. Lactic acidosis rates in type 2 diabetes. Diabetes Care 1998;21:1659-63. DOI ScienceOn |
34 | Almind K, Doria A, Kahn CR. Putting the genes for type II diabetes on the map. Nat Med 2001;7:277-9. DOI ScienceOn |
![]() |