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http://dx.doi.org/10.3746/pnf.2016.21.3.187

Supplementation of a Fermented Soybean Extract Reduces Body Mass and Prevents Obesity in High Fat Diet-Induced C57BL/6J Obese Mice  

Lee, Jae Yeon (R&D Center for Life Science, Biotopia Co., Ltd.)
Aravinthan, Adithan (Department of Physiology, College of Veterinary Medicine, Chonbuk National University)
Park, Young Shik (R&D Center for Life Science, Biotopia Co., Ltd.)
Hwang, Kyo Yeol (R&D Center for Life Science, Biotopia Co., Ltd.)
Seong, Su-Il (R&D Center for Life Science, Biotopia Co., Ltd.)
Hwang, Kwontack (Department of Food and Nutrition, Nambu University)
Publication Information
Preventive Nutrition and Food Science / v.21, no.3, 2016 , pp. 187-196 More about this Journal
Abstract
Obesity is a growing health problem that many countries face, mostly due to the consumption of a Westernized diet. In this present study we observed the effects of a soybean extract fermented by Bacillus subtilis MORI (BTD-1) containing 1-deoxynojirimycin against high fat diet-induced obesity. The results obtained from this study indicated that BTD-1 reduced body weight, regulated hepatic lipid content and adipose tissue, and also affected liver antioxidant enzymes and glucose metabolism. These results suggest that administration of BTD-1 affects obesity by inhibiting hyperglycemia and free radical-mediated stress; it also reduces lipid accumulation. Therefore, BTD-1 may be potentially useful for the prevention of obesity and its related secondary complications.
Keywords
obesity; fermented soybean extracts; glucose metabolism; antioxidant enzymes; lipid accumulation;
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