[KSCI] Korea Science Citation Index Service

http://dx.doi.org/10.3746/pnf.2015.20.4.298

Anti-Obesity Effects of Starter Fermented Kimchi on 3T3-L1 Adipocytes

Lee, Kyung-Hee (Department of Food Science and Nutrition, and Kimchi Research Institute, Pusan National University)
Song, Jia-Le (Department of Food Science and Nutrition, and Kimchi Research Institute, Pusan National University)
Park, Eui-Seong (Department of Food Science and Nutrition, and Kimchi Research Institute, Pusan National University)
Ju, Jaehyun (Department of Food Science and Nutrition, and Kimchi Research Institute, Pusan National University)
Kim, Hee-Young (Department of Food Science and Nutrition, and Kimchi Research Institute, Pusan National University)
Park, Kun-Young (Department of Food Science and Nutrition, and Kimchi Research Institute, Pusan National University)

Publication Information

Preventive Nutrition and Food Science / v.20, no.4, 2015 , pp. 298-302 More about this Journal

Abstract

The anti-obesity effects of starter (Leuconostoc mesenteroides+Lactobacillus plantarum) fermented kimchi on 3T3-L1 adipocyte were studied using naturally fermented kimchi (NK), a functional kimchi (FK, NK supplemented with green tea), and FK supplemented with added starters (FKS). Oil red O staining and cellular levels of triglyceride (TG) and glycerol were used to evaluate the in vitro anti-obesity effects of these kimchis in 3T3-L1 cells. The expressions of adipogenesis/lipogenesis-related genes of peroxisome proliferator-active receptor (PPAR)- ${\gamma}$ , CCAAT/enhance-binding protein (C/EBP)- ${\alpha}$ , and fatty acid synthase (FAS) were determined by RT-PCR. Kimchis, especially FKS, markedly decreased TG levels and increased levels of intracellular glycerol and lipid lipolysis. In addition, FKS also reduced the mRNA levels of PPAR- ${\gamma}$ , C/EBP- ${\alpha}$ , and FAS, which are related to adipogenesis/lipogenesis in 3T3-L1 cells. These results suggest the anti-obesity effects of FKS were to due to enhanced lipolysis and reduced adipogenesis/lipogenesis in 3T3-L1 adipocytes.

Keywords

kimchi; starters; antiobesity; 3T3-L1 cells;

Citations & Related Records

Times Cited By KSCI : 5 (Citation Analysis)

Reference
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