Anti-inflammatory Activity of Stevia rebaudiana in LPS-induced RAW 264.7 Cells |
Jeong, Il-Yun
(Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute)
Lee, Hyo-Jung (Department of Life Science, Gwangju Institute of Science and Technology) Jin, Chang-Hyun (Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute) Park, Yong-Dae (Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute) Choi, Dae-Seong (Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute) Kang, Min-Ah (AI Control Material Research Center, Korea Research Institute of Bioscience and Biotechnology) |
1 | Boonkaewwan C, Ao M, Toskulkao C, Rao MC. 2008. Specific immunomodulatory and secretory activities of stevioside and steviol in intestinal cells. J Agric Food Chem 56: 3777-3784. DOI ScienceOn |
2 | Nathan C. 1992. Nitric oxide: discovery and impact on clinical medicine. FASEB J 92: 164-169. |
3 | Szekancecz Z, Koch E. 2007. Macrophages and their products in rheumatoid arthritis. Curr Opin Rheumatol 19: 289-295. DOI ScienceOn |
4 | Bosca L, Zeini M, Traves G, Hortelano S. 2005. Nitric oxide and cell viability in inflammatory cells: a role for NO in macrophage function and fate. Toxicology 208: 249-258. DOI ScienceOn |
5 | Mormann M, Thederan M, Nackchbandi I. 2008. Lipopolysaccharides (LPS) induce the differentiation of human monocytes to osteoclasts in a tumour necrosis factor (TNF) alpha-dependent manner: a link between infection and pathological bone resorption. Mol Immunol 45: 3330-3337. DOI ScienceOn |
6 |
Baeuerle A, Henkel T. 1994. Function and activation of NF- |
7 |
Baldwin R. 1996. The NF- |
8 | Jeppesen PB, Gregersen S, Alstrup KK, Hermansen K. 2002. Stevioside induces antihyperglycaemic, insulinotropic and glucagonostatic effects in vivo: studies in the diabetic Goto-Kakizaki (GK) rats. Phytomedicine 9: 9-14. DOI ScienceOn |
9 | Ghanta S, Banerjee A, Poddar A, Chattopadhyay S. 2007. Oxidative DNA damage preventive activity and antioxidant potential of Stevia rebaudiana (Bertoni) Bertoni, a natural sweetener. J Agric Food Chem 55: 10962-10967. DOI ScienceOn |
10 | Chaiwat B, Chaivat T, Molvibha V. 2006. Anti-inflammatory and immunomodulatory activities of stevioside and its metabolite steviol on THP-1 cells. J Agric Food Chem 54: 785-789. DOI ScienceOn |
11 | Gerszten RE, Garcia-Zepeda EA, Lim YC, Yoshida M. 1999. MCP-1 and IL-8 trigger firm adhesion of monocytes to vascular endothelium under flow condition. Nature 398: 718-723. DOI ScienceOn |
12 | Charo IF, Taubman MB. 2004. Chemokines in the pathogenesis of vascular disease. Circ Res 95: 858-866. DOI ScienceOn |
13 | Sun Z, Andersson R. 2002. NF-kappaB activation and inhibition: a review. Shock 18: 99-106. DOI ScienceOn |
14 | Chan P, Tomlinson B, Chen Y, Liu J, Hsieh M, Cheng J. 2002. A double-blind placebo controlled study of the effectiveness and tolerability of oral stevioside in human hypertension. Clin Pharmacol 50: 215-220. |
15 | Clancy RM, Amin AR. 1998. The role of nitric oxide in inflammation and immunity. Arthritis Rheum 41: 1141-1151. DOI ScienceOn |
16 | Salas M, Gironella M, Salasa M. 2002. Nitric oxide supplementation ameliorates dextran sulfate sodium-induced colitis in mice. Lab Invest 82: 597-607. DOI ScienceOn |
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