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http://dx.doi.org/10.3746/jfn.2009.14.4.277

Free Radical Scavenging Activity and Protective Ability of Methanolic Extract from Duchesnea indica Against Protein Oxidation and DNA Damage  

Hu, Weicheng (School of Biotechnology, Kangwon National University)
Shen, Wei (College of Guangling, Yangzhou University)
Wang, Myeong-Hyeon (School of Biotechnology, Kangwon National University)
Publication Information
Preventive Nutrition and Food Science / v.14, no.4, 2009 , pp. 277-282 More about this Journal
Abstract
The antioxidant potency of methanolic extract of Duchesnea indica (MDI; Indian strawberry) was investigated by employing various established in vitro systems, such as total phenolic content, 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging activity, reducing power assay, metal chelating assay, superoxide radical scavenging activity and protective ability of DNA damage and protein oxidation. MDI inhibited metal chelating by 75.57% at 2 mg/mL, scavenged 50% DPPH free radical at 29.13 ${\mu}$g/mL, and eliminated approximately 46.21% superoxide radical at the concentration of 1 mg/mL. In addition, MDI showed strong ability on reducing power, DNA damage protection and protein oxidation protection. Overall, results suggested that MDI might be beneficial as a potent antioxidant and effectively employed as an ingredient in food applications.
Keywords
Duchesnea indica; reactive oxygen species; antioxidant; DNA damage; protein oxidation;
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