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http://dx.doi.org/10.3746/jfn.2007.12.2.119

Tyrosinase Inhibition and Mutagenicity of Phenolic Compounds from Mulberry Leaves - Research Note -  

Kim, Young-Chan (Korea Food Research Institute)
Takaya, Yoshiaki (Faculty of Pharmacy, Meijo University)
Chung, Shin-Kyo (Department of Food Science and Technology, Kyungpook National University)
Publication Information
Preventive Nutrition and Food Science / v.12, no.2, 2007 , pp. 119-121 More about this Journal
Abstract
The tyrosinase inhibition activity and mutagenicity as assessed by the Ames test on phenolic antioxidants (5-Caffeoyl quinic acid, 3,4-Dihydroxy cinnamic acid, Quercetin 3-O-${\beta}$-D-glucopyranose, Kaempferol 3-O-${\beta}$- D-glucopyranose) and the ethyl acetate fraction isolated from mulberry leaves were examined. The ethyl acetate fraction and chlorogenic acid exhibited weaker tyrosinase inhibitory activities than kojic acid. In addition, the ethyl acetate fraction from mulberry leaves, containing phenolic antioxidants, showed no mutagenicity by the Ames test.
Keywords
mulberry leaves; chlorogenic acid; tyrosinase inhibition; mutagenicity;
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