Protective Effect of Acanthopanax senticosus Extract on Alloxan-induced β-cell Damage |
Rho, Hye-Won
(Department of Biochemistry, Medical School and Chonbuk National University, Institute of Cardiovascular Research, Chonbuk National University)
Lee, Ji-Hyun (Department of Biochemistry, Medical School and Chonbuk National University) Kim, Jong-Suk (Department of Biochemistry, Medical School and Chonbuk National University) Kim, Hyung-Rho (Department of Biochemistry, Medical School and Chonbuk National University) Park, Byung-Hyun (Department of Biochemistry, Medical School and Chonbuk National University) Park, Jin-Woo (Department of Biochemistry, Medical School and Chonbuk National University) |
1 | Heikkila RE, Winston B, Cohen G, Barden H. 1976. Alloxan-induced diabetes-evidence for hydroxyl radical as a cytotoxic intermediate. Biochem Pharmacol 25: 1985-1092 |
2 | Cohen G, Heikkila RE. 1974. The generation of hydrogen peroxide, superoxide radical by 6-hydroxyl dopamine, dialuric acid and related agents. J Biol Chem 49: 2447-2452 |
3 | Park BH, Rho HW, Park JW, Cho GG, Kim JS, Chung HT, Kim HR. 1995. Protective mechanism of glucose against alloxan-induced pancreatic -cell damage. Biochem Biophys Res Commun 210: 1-6 DOI ScienceOn |
4 | Grakvist K, Marklund S, Sehlin J, Taljedal IB. 1979. Superoxide dismutase, catalase and scavengers of hydroxyl radical protect against the toxic action of alloxan on pancreatic islet cells in vitro. Biochem J 182: 17-25 DOI |
5 | Fischer LJ, Hambruger SA. 1980. Inhibition of alloxan action in isolated pancreatic islets by superoxide dismutase, catalase and metal chelator. Diabetes 29: 213-216 DOI ScienceOn |
6 | Grakvist K, MarkIund SL, Taljedal IB. 1981. Superoxide dismutase is a prophylatic against alloxan diabetes. Nature 294: 158-160 DOI ScienceOn |
7 | Kim HR, Rho HW, Park BH, Park JW, Kim JS, Kim UH, Chung MY. 1994. Role of in alloxan-induced pancreatic -cell damage. Biochim Biophys Acta 1227: 87-91 DOI ScienceOn |
8 | Steinmann GG, Esperester A, Joller P. 2001. Immunopharmacological in vitro effects of Eleutherococcus senticosus extracts. Arzneimittelforschung 51: 76-83 |
9 | Glatthaar-Saalmuller B, Sacher F, Esperester A. 2001. Antiviral activity of an extract derived from roots of Eleutherococcus senticosus. Antiviral Res 50: 223-228 DOI ScienceOn |
10 | Hibasami H, Fujikawa T, Takeda H, Nishibe S, Satoh T, Fujisawa T, Nakashima K. 2000. Induction of apoptosis by Acanthopanax senticosus HARMS and its component, sesamin in human stomach cancer KATO III cells. Oncol Rep 7: 1213-1216 |
11 | Wagner H, Norr H, Winterhoff H. 1994. Plant adaptogens. Phytomedicine 1: 63-76 DOI |
12 | Rosengard BR, Cochrane DE. 1983. Complement-mediated cytolysis: A quick, simple method for determining levels of immunoglobulin E bound to mast cells. J Histochem 31: 441-444 |
13 | Dunn JS, Sheehan HL, McLetchie NG. 1943. Necrosis of Langerhans produced experimentally. Lancet I: 484-487 |
14 | Heikkila RE, Barden H, Cohen G. 1974. Prevention of alloxan-induced diabetes by ethanol administration. J Pharmacol Exp Ther 190: 501-506 |
15 | Boquist L, Nelson L, Lorentzon R. 1983. Uptake of labeled in mouse organs and mitochondria in vivo and in vitro. Endocrinol 113: 943-948 DOI ScienceOn |
16 | Ashcroft SJH, Hammonds P, Harrison DE. 1986. Insulin secretory responses of a clonal cell line of simian virus 40-transfected B cells. Diabetologia 29: 727-733 DOI ScienceOn |
17 | Thaete LG. Grouch RK, Buse MG, Spicer SS. 1985. The protective role of copper-zinc superoxide dismutase against alloxan-induced diabetes: morphological aspects. Diabetologia 28: 677-682 DOI ScienceOn |
18 | Gold G, Walker MD, Edwards DL, Grodsky GM. 1988. Biosynthetic regulation of endogenous hamster insulin and exogenous rat insulin II in transfected HIT cells. Diabetes 37: 1509-1514 DOI ScienceOn |
19 | Malaisse WJ, Malaisse-Lagae F, Sener A, Pipeleers DG. Determinants of the selective toxicity of alloxan to the pancreatic B cell. Proc Natl Acad Sci USA 79: 927-930 |
20 | Rerup CC. 1970. Drugs producing diabetes through damage of insulin secreting cells. Pharmacol Rev 22: 485-518 |
21 | Heikkila RE, Cabbat FS. 1978. Protection against alloxaninduced diabetes in mice by the hydroxyl radical scavenger dimethylurea. Eur J Pharmacol 52: 57-60 DOI ScienceOn |
22 | Heikkila RE, Cabbat FS. 1982. The prevention of alloxaninduced diabetes in mice by the iron-chelator detapac: suggestion of a role for iron in the cytotoxic process. Experientia 38: 378-379 DOI ScienceOn |
23 | Okamoto H. 1985. Molecular basis of experimental diabetes: Degeneration, oncogenesis and regeneration of pancreatic -cells of islet of Langerhans. Bio Assay 2: 15-21 |
24 | Kim HR, Rho HW, Park JW, Kim JS, Kim UH, Jhee EC. 1991. Protection of alloxan-induced -cell damage of rat pancreas by -antagonists. Kor J Biochem 23: 141-146 |
25 | Yamamoto H, Uchigata Y, Okamoto H. 1981. DNA strand breaks in pancreatic islets by in vivo administration of alloxan or streptozotocin. Biochem Biophys Res Commun 103: 1014-1020 DOI ScienceOn |
26 | Margaret MT, Irwin F. 2001. Methods of detection of vascular reactive species: nitric oxide, superoxide, hydrogen peroxide, and peroxynitrite. Circ Res 89: 224-236 DOI ScienceOn |
27 | Miller FJ, Gutterman DD, Rios CD, Heistad DD, Davidson BL. 1998. Superoxide production in vascular smooth muscle contributes to oxidative stress and impaired relaxation in atherosclerosis. Circ Res 82: 1298-1305 DOI ScienceOn |
28 | Bemofsky C, Swan M. 1973. An improved cycling assay for nicotinamide adenine dinucleotide. Anal Biochem 53: 452-458 DOI ScienceOn |
29 | Takasu N, Asawa T, Komiya I, Nagasawa Y, Yamada T. 1991. Alloxan-induced DNA strand breaks in pancreatic islets: Evidence for as an intermediate. J Biol Chem 266: 2112-2114 |
30 | Cooperstein SJ, Watkins D. 1978. Effect of sulfuydryl binding reagents on islet tissue permeability: Protection and reversal by D-glucose and Phlorizin. J Pharmacol Exp Ther 204: 230-239 |
31 | Gandy SE, Buse MG, Crouch PK. 1982. Protective role of superoxide dismutase against diabetogenic drugs. J Clin Invest 70: 650-658 DOI |
32 | Abdel-Rahman MS, Elrakhawy FI, Iskander FA. 1992. Protection of -cells against the effect of alloxan. Toxicol Lett 63: 155-164 DOI ScienceOn |
33 | Sui DY, Lu ZZ, Li SH, Cai Y. 1994. Hypoglycemic effect of saponin isolated from leaves of Acanthopanax senticosus (Rupr. et Maxin.) Harms. Zhongguo Zhong Yao Za Zhi 19: 683-685 |
34 | Royall JA, Ischiropoulos H. 1993. Evaluation of 2',7'dichlorofluorescin and dihydrorhodamine 123 as fluorescent probes for intracellular in cultured endothelial. Cells Arch Biochem Biophys 302: 348-355 DOI ScienceOn |