Effect of Onion Extract on the Carbon Tetrachloride-induced Liver Injury in Mouse |
Lee, Kyung-Jin
(Department of Biology, Chonnam National University)
Kim, Deok-Song (Department of Biology, Chonnam National University) Kim, Jong-Sun (Department of Biology, Chonnam National University) Chin, Jong-Eun (Department of Cosmetology, Dongkang College) Kim, Jun-Ho (Department of Pharmacy, Chosun University) Na, Myung-Suk (Department of Environmental Health, Kwangju Women University) Lee, Jong-Bin (Department of Biology, Chonnam National University) |
1 | Lauriault VV, Khan S, O'Brien PJ. 1992. Hepatocyte cytotoxicity induced by various hepatotoxins mediated by cytochrome P-450IIE1: protection with diethyldithiocarbamate administration. Chemico-Biological Interactions 81: 271-289 DOI ScienceOn |
2 | Marzouk MS, El-Toumy SA, Moharram FA, Shalaby NM, Ahmed AA. 2002. Pharmacologically active ellagitannins from Terminalia myriocarpa. Planta Med 68: 523-527 DOI ScienceOn |
3 | Dicker E, McHugh T, Cederbaum AI. 1990. Increased oxidation of p-nitrophenol and aniline by intact hepatocytes isolated from pyrazole-treated rats. Biochimica et Biophysica ACTA 1035: 249-256 DOI ScienceOn |
4 | Ursini F, Maiorino M, Morazzoni P, Roveri A, Pifferi G.1994. A novel antioxidant flavonoid affecting molecular mechanisms of cellular activation. Free Radic Biol Med 16: 547-553 DOI ScienceOn |
5 | Recknagel RO, Glende EAJr, Britton RS. 1991. Free radical damage and lipid peroxidation. In Hepatotoxicology. Meeks RG, ed. CRC Press, Florida. p 401-436 |
6 | Brent JA, Rumack BH. 1993. Role of free radicals in toxic hepatic injury 11. Clinical Toxicology 31: 173-196 DOI ScienceOn |
7 | Jeong HG, Park HY. 1998. The prevention of carbon tetrachloride-induced hepatotoxicity in mice by-hederin: inhibition of cytochrome P450 2E1 expression. Biochemistry and Molecular Biology International 45: 163-170 |
8 | Campo GM, Squadrito F, Ceccarelli S, Calo M, Avenoso A, Campo S, Squadrito G, Altavilla D. 2001. Reduction of carbon tetrachloride-induced rat liver injury by IRFI 042, a novel dual vitamin E-like antioxidant. Free Radical Biology and Medicine 34: 379-393 DOI ScienceOn |
9 | Dorsch W. 1996. Allium cepa L. (onion). Part 2: chemistry, analysis and pharmacology. Phytomedicine 3: 391-397 |
10 | Helen A, krishnakumar K, Vijayammal PL, Augusti KT.2000. Antioxidant effect of onion oil (Allium cepa. Linn)on the damages induced by nicotine in rats as compared to alpa-tocopherol. Toxicol Lett 116: 61-68 DOI ScienceOn |
11 | Teyssier C, Amiot MJ, Mondy N, Auger J, Kahane R, Siess MH. 2001. Effect of onion consumption by rats on hepatic drug-metabolizing enzymes. Food Chem Toxicol 39: 981-987 DOI ScienceOn |
12 | Fairhurst S, Barber DJ, Clark B, Horton AA. 1982. Studies on paracetamol-induced lipid peroxidation. Toxicology 23: 249-259 DOI ScienceOn |
13 | Lee KJ, Jeong HG. 2002. Protective effect of Platycodi radix on carbone tetrachloride-induced hepatotoxicity. Food Chem Toxicol 40: 517-525 DOI ScienceOn |
14 | Brattin WJ, Glende EAJr, Recknagel RO. 1985. Pathological mechanisms in carbon tetrachloride hepatotoxicity.Journal of Free Radical Biology & Medicine 1: 27-38 DOI ScienceOn |
15 | Williams AT, Burk RF. 1990. Carbon tetrachloride hepatotoxicity: an example of free radical-mediated injury. Seminars in Liver Disease 10: 279-284 DOI ScienceOn |
16 | Koop DR. 1992. Oxidative and reductive metabolism by cytochrome P450 2E1. FASEB J 6: 724-730 |
17 | Zangar RC, Benson JM, Burnett VL, Springer DL. 2000. Cytochrome P4502El is the primary enzyme responsible for low-dose carbon tetra-chloridemetabolism in human liver microsomes. Chem Biol Interact 125: 233-243 DOI ScienceOn |
18 | Kim ND, Kwak MK, Kim SG. 1997. Inhibition of cytochrome P450 2E1 expression by 2-(allylthio)pyrazine, a potential chemoprotective agent: hepatoprotective effects. Biochem Pharmacol 53: 261-269 DOI ScienceOn |
19 | Jeong HG. 1999. Inhibition of cytochrome P450 2El expression by oleanolic acid: hepatoprotective effects against carbon tetrachloride-induced hepatic injury. Toxicol Lett 105: 215-222 DOI ScienceOn |
20 | Guengerich FP, Kim D-H, Iwasaki M. 1991. Role of human cytochrome P-450 IIE1 in the oxidation of many low molecular weight cancer suspects. Chemical Research in Toxicology 4: 168-179 DOI ScienceOn |
21 | Jeong HG, Yun CH. 1995. Induction of rat hepatic cytochrome enzymes by myristicin. Biochem Biophys Res Commun 217: 966-971 DOI ScienceOn |
22 | Sedlak J, Lindsay RH. 1968. Estimation of total protein with bound and non-protein sulthydryl groups in tissues with Ellman's reagent. Analytical Biochemistry 25: 192-205 DOI ScienceOn |
23 | Recknagel RO, Glende EAJr, Dolak JA, Waller RL. 1989. Mechanisms of carbon tetrachloride toxicity. Pharmacology and Therapeutics 43: 139-154 DOI ScienceOn |
24 | Bradford MM. 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Biochemistry 72: 248-254 |
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