Browse > Article
http://dx.doi.org/10.5713/ajas.2006.459

Relationship between the Polymorphisms of 5' Regulation Region of Prolactin Gene and Milk Traits in Chinese Holstein Dairy Cows  

Li, J.T. (Institute of Animal Science, Chinese Academy of Agricultural Sciences)
Wang, A.H. (Institute of Animal Science, Chinese Academy of Agricultural Sciences)
Chen, P. (College of Animal Science & Technology, China Agricultural University)
Li, H.B. (Institute of Animal Science, Chinese Academy of Agricultural Sciences)
Zhang, C.S. (Institute of Animal Science, Chinese Academy of Agricultural Sciences)
Du, L.X. (Institute of Animal Science, Chinese Academy of Agricultural Sciences)
Publication Information
Asian-Australasian Journal of Animal Sciences / v.19, no.4, 2006 , pp. 459-462 More about this Journal
Abstract
Prolactin (PRL) plays an important role in promoting mammalian mammary gland development, and milk production during lactation. Therefore the PRL gene was chosen as a candidate gene for milk traits in Holstein dairy cows. PCR-SSCP and PCR-RFLP were used to analyze genetic variations in the 5' regulation region of the PRL gene. In this part of the gene, two new polymorphic sites were detected in the Chinese Holstein dairy cows. One was a XbaI-RFLP locus, and the other was an SSCP locus. Statistical analysis showed that the XbaI-RFLP locus and the SSCP locus had a significant positive effect on milk traits.
Keywords
Prolactin (PRL); PCR-RFLP; PCR-SSCP; Milk Traits;
Citations & Related Records

Times Cited By Web Of Science : 3  (Related Records In Web of Science)
Times Cited By SCOPUS : 4
연도 인용수 순위
1 Ashwell, M. S., Y. Da, C. P. Van Tassell, P. M. Vanraden, R. H. Miller and C. E. Rexroad Jr. 1998. Detection of putative loci affecting milk production and composition, health and type traits in a US Holstein population. J. Dairy Sci. 81:3309-3314   DOI   ScienceOn
2 Cao, X., Q. Wang, J. B. Yan, F. K. Yang, S. Z. Huang and Y. T. Zeng. 2002. Molecular cloning and analysis of bovine prolactin full-long genomic as well as cDNA sequences. Yi Chuan Xue Bao. 29(9):768-773
3 Shadparvar, A. A. and M. S. Yazdanshenas. 2005. Genetic parameters of milk yield and milk fat percentage test day records of Iranian Holstein cows. Asian-Aust. J. Anim. Sci. 18(9):1231-1236   DOI
4 Truong, A. T., C. Duez, A. Belayew, A. Renard, R. Pictet, G. I. Bell and J. A. Martial. 1984. Isolation and characterization of the human prolactin gene. Embo. J. 3(2):429-437
5 Wang, W. J., L. S. Huang, J. Gao, N. S. Ding, K. F. Chen, J. Ren and M. Luo. 2003. Polymorphism of growth hormone gene in 12 pig breeds and its relationship with pig growth and carcass traits. Asian-Aust. J. Anim. Sci. 16(1):161-164   DOI
6 Han, S. K., Y. C. Shin and H. D. Byun. 2000. Biochemical, molecuar and physiological characterization of a new betacasein variant detected in Korean cattle. Anim. Genet. 31(1):49-51   DOI   ScienceOn
7 Hart, G. L., J. Bastiaansen, M. R. Dentine and B. W. Kirkpatrick. 1993. Detection of a four-allele single strand conformation polymorphism (SSCP) in the bovine prolactin gene 5' flank. Anim. Genet. 24(2):149
8 Chrenek, P., J. Huba, D. Vasicek, D. Peskovicova and J. Bulla. 2003. The relation between genetic polymorphism markers and milk yield in BrownSwiss cattle imported to Slovakia. Asian- Aust. J. Anim. Sci. 16(10):1397-1401   DOI
9 Kohmoto, K., S. Tsunasawa and F. Sakiyama. 1984. Complete amino acid sequence of mouse prolactin. Eur. J. Biochem. 138:227-237   DOI   ScienceOn
10 Cowan, C. M., M. R. Dentine, R. L. Ax and L. A. Schuler. 1990. Structural variation around prolactin gene linked to quantitative traits in an elite Holstein sire family. Theor. Appl. Genet. 79:577-582
11 Goffin, V., N. Binart, P. Touraine and P. A. Kelly. 2002. Prolactin: the new biology of an old hormone. Annu. Rev. Physiol. 64:47-67   DOI   ScienceOn
12 Mao, Y. J., G. H. Zhong, Y. C. Zheng, X. W. Pen, Z. P. Yang, Y. Wang and M. F. Jiang. 2004. Genetic polymorphism of milk protein and their relationships with milking traits in Chinese Yak. Asian-Aust. J. Anim. Sci. 17(11):1479-1483   DOI
13 Wolf, J. B., V. A. David and A. H. Deutch. 1990. Identification of a distal regulatory element in the 5' flanking region of the bovine prolactin gene. Nucleic Acids Res. 18(16):4905-4912
14 Marc, E. F., K. BeLa, L. Anna and N. GyoRgy. 2000. Prolactin: structure, function and regulation of secretion. Physiol. Reviews. 80(4):1523-1631   DOI
15 Stevens, F. R., A. Hajeer, S. John, W. Thomson, J. Worthington, J. R. Davis and W. E. Ollier. 1999. The Bg/II polymorphism of the human prolactin gene lies within intron C and can be detected by PCR/RFLP. Eur. J. Immunogenet. 26(4):261-263   DOI   ScienceOn
16 Udina, I. G., S. O. Turkova, M. V. Kostiuchenko, L. A. Lebedeva and G. E. Sulimova. 2001. Polymorphism of cattle prolactin gene: microsatellites, PSR-RFLP. Genetika. 37(4):511-516
17 Sambrook, J., E. F. Fritsch and T. Maniatis. 1989. Molecular cloning: a laboratory Mannual. Second edition. Cold Spring Harbor Laboatoty Press
18 Bobe, G., D. C. Beitz, A. E. Freeman and G. L. Lindberg. 1999. Effect of milk protein genotypes on milk protein composition and its genetic parameter estimates. J. dairy Sci. 82:2797-2804   DOI   ScienceOn
19 Au, W. L. and F. C. C. Leung. 2002. Rapid communication: Complete nucleotide sequence of the chicken prolactin gene. Anim. Sci. 80(5):1381   DOI