Browse > Article
http://dx.doi.org/10.5187/JAST.2005.47.1.029

Effect of Dietary Brown Seaweed Levels on the Antioxidant System in Broiler Chicks Activated Innate Immune Response  

Lee, H.J. (Department of Animal Life Sciences, Konkuk University)
Park, I.K. (Department of Animal Life Sciences, Konkuk University)
Im, J.T. (Department of Animal Life Sciences, Konkuk University)
Choi, D.Y. (Department of Animal Life Sciences, Konkuk University)
Choi, C.J. (Department of Animal Life Sciences, Konkuk University)
Choi, J.B. (Department of Animal Life Sciences, Konkuk University)
Lee, H.G. (Seoul National University)
Choi, Y.J. (Seoul National University)
Koh, T.S. (Department of Animal Life Sciences, Konkuk University)
Publication Information
Journal of Animal Science and Technology / v.47, no.1, 2005 , pp. 29-38 More about this Journal
Abstract
Effect of dietary brown seaweed(Undaria pinnatifida) levels on the anti-oxidant enzyme system was evaluated in blood of broiler chicks activated innate immune response. Day-old broiler chicks were fed diets containing 0.0(basal), 1.0, 2.0 and 4.0 % of brown seaweed for 4 weeks. The innate immune response was activated by injecting Salmonella typhymurium lipopolysaccharide(LPS) i.p. at 8, 10 and 12 day of age. The activation of innate immune response enhanced(p< 0.01) and the brown seaweed 1.0 and 2.0 % diets reduced(P< 0.05) the superoxide dismutase(SOD) activity in erythrocyte cytosol significantly. The activation of innate immune response elevated significantly the levels of peroxide and the activity of peroxidase in plasma, while the levels of dietary brown seaweed resulted in a significant linear increase in peroxidase activity in plasma of normal bird. Experience of the innate immune response in 4 week-old chicks reduced linearly the plasma level of peroxide with the level of brown seaweed and enhanced the plasma peroxidase activity. Also, the plasma of normal birds fed the brown seaweed showed higher level of peroxide and lower activity of peroxidase. The results indicated that dietary brown seaweed affected SOD and peroxidase activities in blood of broiler chicks during activation of innate immune response.
Keywords
Broiler chicks; Brown seaweed product; Peroxide; Peroxidase; SOD; Innate immunity;
Citations & Related Records
Times Cited By KSCI : 2  (Citation Analysis)
연도 인용수 순위
1 Visner, G. A., Dougall, W. C., Wilson, J. M., Burr, I. A. and Nick, H. S. 1990. Regulation of manganese superoxide dismutase by lipopolysaccharide, inter-leukin-l, and tumor necrosis factor. role in the acute inflamatory response. J. BioI. Chem. 265:2856-2864
2 Del Rio, M., Ruedas, G., Medina, S., Victor, V. M. and De la Fuente, M. 1998. Improvement by several antioxidants of macrophage function in vitro. Life Sci. 63:871-881   DOI   ScienceOn
3 DiSilvestro, R. A., David, E. A. and Collignon, C. 1991. Interleukin-I slowly increases lung fibroblast Cu-Zn superoxide dismutase activity levels. Proc. Soc. Exp. BioI. Med. 197:197-200   DOI
4 Lee, D. S., Kim, H. R., Cho, D. M., Narn, T. J. and Pyeun, J. H. 1998. Uronate compositions of alginates from the edible brown algaer. Han'guk Susan Hakhoechi ,31(1), 1-7.(in Korean)
5 Lowry, O. H, Rosebrough, N. J., Farr, A. L. and Randall, R. J. 1954. Protein mesurement with the Folin phenol reagent. J. BioI. Chem. 193:265-275
6 McCord, J. M. and Fridovich, I. 1969. Superoxide dismutase. An enzyme function for erythrocuprein (hemocuperin). J. BioI. Chem. 244:6049-6055
7 고태송, 임진택, 박인경, 이혜정, 최도열, 최준영, 이홍구, 최윤재. 2005. 급성 기 반응이 활성화한 육계 병아리의 단백질과 에너지대사에 미치는 사료 중 미역제품 수준의 영향, 한국 동물자원과학회지 : 투고중
8 Takahashi, K., Watanuki, Y., Yamazki, M. and Abe, S. 1988. Local induction of a cytotoxic factor in a murine tumor by systemic administration of an antitumor plysacchrdide, MGA. Br. J. Cancer 57:170-173   DOI   ScienceOn
9 Xie, H., Rath, N. C., Huff, G. R., Huff, W. E. and Balog, J. M. 2000, Effects of Salmonella typhymurium Iipopolysacchride on broiler chickens. Poulutry Science, 79:33-40   DOI
10 Wong, G, H. and Gooddel, D. V. 1988. Induction of manganous superoxide dismutase by tumor necrosis factor. Cell 58:923-931
11 Zhao, W., Han, Y., Zhao, B., Horota, S., Hou, J. and Xin, W. 1998. Effect of carotenoids on the respiratory burst of rat peritoneal macrophages. Biochimica et Biophysica Acta 1381:77-88   DOI   ScienceOn
12 Koh, T. S., Peng, R. K. and Klsing, K. C. 1996. Dietary copper level affects copper metabolism during lipopolysaccharide-in-duced immunological stess in chicks. Poultry. Sci., 75(7):867-872   DOI   ScienceOn
13 Jenssen, Y. M. W., Van Houten, B., Bonn, P. J. A. and Mossman, B. T. 1993. Cell and tissue responses to oxidative damage. Lab. Invest. 69:261-274
14 Klasing, K. C. and Korver, D. R. 1997. Leukocytic cytokines regulate growth rate and composition following activation of the immune system. J. Anim. Sci. 75(Suppl,2):58-67p
15 Kogut, M. H., Holtzapple, C., Lowry, V. K., Genovese, K. and Stanker, L. H. 1998. Funtional responses of neonatal chicken and turkey heterophils following stimulation by inflammatory agonists. American Jounal of Veterinary Research 59:1404-1408
16 Koh, T. S., Im, J. T., Park, I. K. and Kim, J. H. 2004 a Effect of dietary krill meal on the performance of broiler chicks during the acute phase response. J. Anim. Sci & Technol. 46(2):173-182. (in Korean)   DOI
17 Korver, D. R. and K1asing, K. C. 1997. Dietary fish oil alters specific and inflammatory immune response, J. Nutr. 2039-2046
18 Lam, K. M. 1997. Myelopeoxidase activity in chicken heterophils and adherent cells. Vererinary Immunology and Immunopathology 3-4:327-335
19 Harmon, B. G. 1998. Avian heterophils in inflammation and disease resistance. Poultry Science 77:972-977.   DOI
20 Halliwell, B. and John Gutteridge, M. C. 2000. Exercise : an oxidative stress. In 'Free Radicals in Biology and Medicine' Third Ed. Oxford University Press, New York
21 Murata, M., Ishihara, K. and Saito, H. 1999. Hepatic fatty acid oxidation enzyme activities are stimulated in rats fed the brown seaweed, Undbria pinnatifida(wakame). J. Nutr. Vol. 132:742-747
22 Otterlei, M., Ostggard, K., Skjaek-Break, G., Smidsrod, O., Soon-Shiong, P. and Espevik, T. 1991. Induction of cytokine production from human monocytes stimulated with alginate. J. Immunother. 10:286-291   DOI
23 Park, I. K., Kim, J. H., Im, J. T. and Koh, T. S. 2004. Effect of the acute phase response on the performance and superoxide dismutase activity in broiler chicks fed on dietary krill meal J. Anim. Sci & Technol. 46(3):183-192.(in Korean)   DOI
24 SAS Institute lnc., 1990. SAS/STAT User's Guide Version 6, Fourth ed. Volume 2, Cary NC: SAS Institute Inc., p. 891
25 Son, E. H, Moon, E. Y., Rhee, D. K. and Pyo, S. 2001. Stimulation of various functions in murine peritoneaı macrophages by high mannuronic acid-containing alginate(HMA) exposure in vivo. International Immunopharmacology. 1:147-154   DOI   ScienceOn
26 Tatzber, F., Griebenow, S., Wonisxh, W. and Winker, R. 2003. Dual method for the determination of peroxidase activity and total peroxidesiodide leads to a significant increase of peroxidase activity in human sera. Analytical Biochemistry 316:147-153   DOI   ScienceOn