Browse > Article
http://dx.doi.org/10.5187/JAST.2004.46.4.525

Identification of Quantitative Trait Loci(QTL) for Meat Color Trait on Chromosome 7 in Pig  

Choi, B.H. (National Livestock Research Institute, RDA)
Lee, H.Y. (National Livestock Research Institute, RDA)
Kim, T.H. (National Livestock Research Institute, RDA)
Hong, K.C. (Division of Biotechnology and Genetic Engineering, Korea University)
Cheong, I.C. (National Livestock Research Institute, RDA)
Publication Information
Journal of Animal Science and Technology / v.46, no.4, 2004 , pp. 525-536 More about this Journal
Abstract
The objective of this study was to identify the quantitative traits loci(QTL) for meat quality traits in pigs. Three-generation resource population was constructed from a cross between Korean native boars and Landrace sows. The resource population including founders, $F_1$ and $F_2$ was genotyped for 23 microsatellite markers on chromosome 7. The sex average total length of linkage map on chromosome 7 was estimated 154.6 cM. Meat quality traits including meat pH, meat color, drip loss, shear force, heating loss, crude fat, crude protein, crude ash and water content in muscle were collected from $F_2$ animals. For the QTL mapping, we used $F_2$ QTL Analysis Servlet of QTL express for web-based QTL mapping tools(http://qtl.cap.ed.ac.uk/). The QTLs for CIE-a and CIE-b on SSC7 were significantly detected at 1% and 5% chromosome-wide level, respectively.
Keywords
QTL mapping; Meat color; Linkage mapping; Microsatellite; Korean native boar;
Citations & Related Records
연도 인용수 순위
  • Reference
1 Andersson, L., Haley, C. S., Ellegren, R, Knott, S. A., Johansson, M., Andersson, K., AnderssonEklund, L., Edfors-Lilja, I., Fredholm, M., Hansson, I., Hakansson, J. and Lundstnn, K. 1994. Genetic mapping of quantitative trait loci for growth and fatness in pigs. Science. 263:1771-1774.
2 Andersson-Eklund, L., Marklund, L., Lundstrom, K., Haley, C. S., Andersson, K., Hansson, I., Moller, M and Andersson, L. 1998. Mapping quantititative trait loci for carcass and meat traits in a Wild boar x Large White intercross. J. Anim. Sci. 76:694-700.
3 A. O. A. C. 1990. 'Official Methods of Analysis' 15th ed. Assosiation of Official Analytical Chemists. Washington, D. C.
4 Archibald, A. L., Haley, C. S., Brown, J. F., Couperwhite, S., McQueen, H. A., Nicholson, D., Coppieters, W., Vendeweghe, A., Stratil, A., Wintero, A. K., Fredholm, M., Larsen, N. J., Nielsen, V. H., Milan, D., Woloszyn, N., Robie, A., Dalens, M., Riquet, J., Gellin, J., Caritez, J. C., Burgaud, G., Ollivier, L., Bidanel, J. P., Vaiman, M., Renard, C; Geldermann, H, Davoli, R, Ruyter, D., Verstege, E. J. M., Groenen, M A. M, Davies, W., Hoyheim, B., Keiserud, A., Andersson, L., Ellegren, H, Johansson, M., Marklund, L., Miller, J. R, Dear, D. V. R, Signer, E., Jeffreys, A.J., Moran, c, Letissier, P., Rothschild, M. F., Tuggle, C. K., Vaske, D., Helm, J., Liu, H. C., Rahman, A., Yu, T. P., Larson, R G. and Schmitz, C. B. 1995. The Pigmap Consortium linkage map of the pig(Sus scrofa). Mamm. Genome. 6:157-175.   DOI   ScienceOn
5 Bidanel, J. P., Milan, D., Iannuccelli, N., Amigues, Y., Boscher, M. Y., Bourgeois, F., Caritez, J. C., Gruand, J., Le Roy, P., Lagant, H, Quintanilla, R, Renard, C., Gellin, J., OIlivier, L. and Chevalet, C. 2001. Detection of quantitative trait loci for growth and 'fatness in pigs. Genet. Sei. Evoi. 33:289-309.
6 Cameron, N. D. 1990. Comparison of Duroc and British Landrace pigs and the estimation of genetic and phenotypic parameters for growth and carcass traits. Animal Production. 50:141.
7 Clutter, A. C. 1995. Presented to the National Swine Improvement Federation, Des Moines, Iowa, December I.
8 Dekkers, J. C. M., Rothschild, M. F. and Malek, M. M. 2001. Potential and application of marker assisted selection for meat quality. Second international Virtual Conference on Polk Quality. November, 05 to December, 06-2001.
9 Bovenhuis, H, Groenen, M. A. M. and Brascamp, W. E. 2000. Detection and characterization of quantitative trait loci for carcass and meat quality traits in pigs. Proc. Europ. Assoc. Anim. Prod. 6:3.
10 De Koning, D., Harlizius, B., Rattink, A. P., Groenen, M. A. M., Brascamp, E. W. and van Arendonk, J. A. M. 2001. Detection and characterization of quantitative trait loci for meat quality traits in pigs. J. Anim. Sci. 79:2812-2819.
11 Devol. D. L., Mckeith, F. K., Bechtel, R S., Novakofski. J., Shanks. R D. and Carr, T. R 1988. Variation in composition and palatability traits and relationships between muscle characteristics and palatability in a random sample of pork carcasses. J. Anim. Sci. 66:385.
12 Green, P., Falls, K. and Crooks, S. 1990. Documentation for CRIMAP, version 2.4. Washington Univ. School of Medicine, St. Louis, MO.
13 Huff-Lonergan E., Baas T. J., Malek M., Dekkers J. C. M. and Pursa K. 2001. orrelations among selected pork quality traits. J. Anim. Sci. Submitted.
14 Knott, S. A, Markhmd, L., Haley, C. S., Andersson, K., Davies, W., Ellegren, H., Fredholm, M., Hansson, I., Hoyheim, B., Lundstrom, K., Moller, M. and Andersson, L. 1998. Multiple marker mapping of quantitative trait loci in a cross between outbred wild boar and large white pigs. Genetics. 149:1069-1080.
15 Kim, K. S., Larsen, N., Short, T., Plastow, G. and Rpthschild, M. F. 2000. A missence variant of the porcine melanocortin-4 receptor(MC4R) gene is associated with fatness, growth, and feed intake traits. Mamm. Genome. 11: 131-135.   DOI   ScienceOn
16 Kranen, R W., van Kuppevelt, T. H., Goedhart, H. A., Veerkamp, C. H., Larnbooy, E. and Veerkamp, J. H. 1999. Hemoglobin and myoglobin content in muscles of broiler chickens. Poult. Sci. Mar.;78(3):467-76.   DOI
17 Lee, H. Y. 2003. Detection of Quantitative Traits Loci(QTL) in pig by using microsatellite markers. A Dissertation for the Degree of Master of Science, Korea University.
18 Paszek, A. A., Wilkie, P. J., Flickinger, G. H., Rohrer, G. A., Alexander, L. J., Beattie, C. W. and Schook, L. B. 1999. Interval mapping of growth in divergent swine cross. Marnm. Genome. 10:117-122.   DOI   ScienceOn
19 Malek, M., Dekkers, J. C. M., Lee, H. K., Baas, T. and Rothschild, M. F. 2001. A molecular genome scan analysis to identify chromosomal reo gions influencing economic traits in the pig. II. Meat and muscle composition. Marnm. Genome. 12:637-645.   DOI   ScienceOn
20 Ovilo, C., Oviler, A., Noguera, J. L,. Clop, A., Barragan, C., Varona, L., Rodriguez, C., Toro, M., Sanchez, A., Perez-Enciso, M. and Silio, L. 2002. Test for positional candidate genes for body composition on pig chromosome 6. Genet. Sel. Evol. 34(4):465-479.
21 Perez-Enciso, M., Clop, A., Folch, J. M., Sanchez, A., Oliver, M. A., Ovilo, C., Barragan, C, Varona, L. and Noguera, J. L. 2002. Exploring Alternative Models for Sex-Linked Quantitative Trait Loci in Outbred Population. Application to an iberian x landrace pigs intercross. Genetics. Aug;161(4):1625-1632.
22 Rohrer, G. A., Alexander, L. J., Hu, Z., Smith, T. P. L., Keele, J. W. and Beattie, C. W. 1996. A comprehensive map of the porcine genome. Genome Res. 6:371-391   DOI   ScienceOn
23 Rohrer, G. A. and Keele, J. 1998. Identification of quantitative trait loci affecting carcass composition in swine I. Fat deposition traits. J. Anim. Sci. 76:2247-2254.
24 Rothschild, M. F. and Soller, M. 1997. Candidate gene analysis to detect genes controlling traits economic importance in domestic livestock. Probe. 8:13-20.
25 Ryoichi, S., Degychi, T. and Nagata, Y. 1993. Effectiveness of the filter paper press method for determining the water holding capacity of meat Fleischwirtsch, 73:1399.
26 Falconer, D. S. 1981. Introduction to Quantitative Genetics (2nd edn.). Longman House, London.
27 진상근, 김철욱, 송영민, 장원혁, 김영보, 여정수, 김재우, 강근호. 2001. 랜드레이스와 재래돼지육의 이화학적 특성. 한국축산식품학회지. Vol. 21. No. 2 p. 142-148.
28 Fujii, J., Otsu, K., Zorzto, F., de Leon, S., Khanna, V. K., Weiler, J. E., O'Brien, P. J. and Maclennan, D. H. 1991. Identification of a mutation in porcine ryanodine receptor associated with malignant hyperthermia. Science. 253:448-451.   DOI
29 Gerbens, F., van Erp, A. J., Harders, F. L., Verburg, F. J., Meuwissen, T. H., Veerkamp, J. H. and te Pas, M. F. 1999. Effect of genetic variants of the heart fatty acid-binding protein gene on intramuscular fat and performance traits in pigs. J Anim Sci. 77:846-852.   DOI
30 박범영, 유영모, 조수현, 채현석, 김진형, 안종남, 이종문, 윤상기. 2001. Hunter L 값에 따른 돈육의 육질 특성 연구. 한국축산식품학회지. Vol. 21. No. 4 pp. 323-328.
31 축산기술연구소, 농협중앙회. 2002. 새로운 돼지사육기술.
32 Wang, L., Yu, T. P., Tuggle, C. K., Liu, H. C. and Rothschild, M. F. 1998. A directed search for quantitative trait loci on chromosomes 4 and 7 in the pig. J. Anim. Sci. 76:2560-2567.   DOI
33 Maribo, H., Olsen, E. V., Patricia, B. G., Anders, J. N. and Anders, K. 1998. Effect of early post-mortem cooling on temperature, pH fall and meat quality in pigs. Meat Sci., 50, 115.
34 Marklund, L., Moller, M., Hoyheim, B., Davies, W., Fredholm, M., Juneja, R K., Mariani, P., Coppieters, W., Ellegren, H. and Andersson, L. 1996. A comprehensive linkage map of the pig based on a wild pig-Large White intercross. Anim. Genet. 27:255-269.
35 Mikawa, S., Akita, T., Hisamatsu, N., Inage, Y., Ito, Y., Kobayashi, E., Kusumoto, H., Matsumoto, T., Mikami, H., Minezawa, M., Miyake, M., Shimanuki, S., Sugiyama, C, Uchida, Y., Wada, Y., Yanai, S. and Yasue, H. 1999. A linkage map of 243 DNA markers in an intercross of Gottingen miniature and Meishan pigs. Anim. Genet. 30:407-417.
36 Sellier, P. 1998. Genetics of meat and carcass traits. In :Rothschild, M.F., Ruvinsky, A.(Eds.), The genetics of the pig. CABI, Wallingford, UK.
37 Van der WaI, P. G., Engel, B. and Hulsegge, B. 1997. Causes for variation in pork quality. Meat Sci. 46(4):319
38 Warriss, P. D. and Brown, S. N. 1987. The relationships between initial pH, reflectance and exudation in pigs muscle. Meat Sci., 20, 65-74.