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http://dx.doi.org/10.5851/kosfa.2012.32.1.24

Effects of Bifidus Enhancer Yogurt on Relief from Loperamide-induced Constipation  

Choi, Jin-Hee (Department of Food and Nutrition, Sookmyung Women's University)
Jeong, Seung-Hwan (Research & Development Center, Namyang Dairy Products Co., Ltd.)
Cho, Young-Hoon (Research & Development Center, Namyang Dairy Products Co., Ltd.)
Cho, Yun-Kyung (Research & Development Center, Namyang Dairy Products Co., Ltd.)
Choi, Hae-Yeon (Department of Home Economics Education, Kongju National University)
Kim, Sun-Im (Department of Food and Nutrition, Sookmyung Women's University)
Publication Information
Food Science of Animal Resources / v.32, no.1, 2012 , pp. 24-30 More about this Journal
Abstract
This study investigated the effects of bifidus enhancer yogurt (BEY) on loperamide-induced constipation in rats. The bifidus enhancer, made of rice-DDGS (Dried Distillers Grains with Solubles), improved proliferation of bifidobacteria (BB-12). Male SD rats were induced with constipation using loperamide and were then used to test the effectiveness of BEY in relieving constipation. The rats were divided into four groups: normal group (NOR), loperamide-treated group (LOP), bifidus enhancer yogurt and loperamide-treated group (L-BEY), and commercial yogurt and loperamide-treated group (L-CY). Treatment of loperamide reduced the wet weight and water content of fecal pellets, but increased the number of fecal pellets in the distal colon. Meanwhile, the fecal weight of the L-BEY group showed an increase of 43% and 23% versus the LOP and L-CY group, respectively. Also, the fecal water content in the L-BEY group was 14.5% and 6.8% higher than that in the LOP and L-CY group, respectively. In addition, the L-BEY group had the fewest fecal pellets in the distal colon. In the serum lipid parameters, the LOP group had a HDL/total cholesterol ratio that was 43% lower than the NOR group, but the L-BEY group had 27% lower than NOR group. These results suggest that bifidus enhancer yogurt has superior effects when it comes to relieving loperamide-induced constipation in rats.
Keywords
bifidus-enhancer yogurt; rice-DDGS; constipation; loperamide;
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