Simultaneous Determination of Vitamin A and E in Infant Formula by HPLC with Photodiode Array Detection
![]() ![]() |
Lee, Hong-Min
(Food Safety Center, Research and Development Institute, Namyang Dariy Co., Ltd.)
Kwak, Byung-Man (Food Safety Center, Research and Development Institute, Namyang Dariy Co., Ltd.) Ahn, Jang-Hyuk (Food Safety Center, Research and Development Institute, Namyang Dariy Co., Ltd.) Jeong, Seung-Hwan (Food Safety Center, Research and Development Institute, Namyang Dariy Co., Ltd.) Shim, Sung-Lye (Department of Food and Nutrition, Chosun University) Kim, Kyong-Su (Department of Food and Nutrition, Chosun University) Yoon, Tae-Hyung (Nutrition and Functional Food Research Team, Korea Food and Drug Administration) Leem, Dong-Gil (Nutrition and Functional Food Research Team, Korea Food and Drug Administration) Jeong, Ja-Young (Nutrition and Functional Food Research Team, Korea Food and Drug Administration) |
1 | Speek, A. J., Schrijver, J., and Schreurs, W. H. P. (1985) Vitamin E composition of some seed oils as determined by highperformance liquid chromatography. J. Food Sci. 50, 121-124. |
2 | Syvaoja, E. L., Piironen, V., Varo, P., Koivistoinen, P., and Salminen, K. (1985) Tocopherols and tocotrienols in Finnish food: human milk and infant formulas. Int. J. Vitam. Nutr. Res. 55, 159-166. |
3 | Tuan, S., Lee, T. F., Chou, C. C., and Wei, Q. K. (1989) Determination of vitamin E homologues in infant formulas by HPLC using fluorometric detection. J. Micronutr. Anal. 6, 35-45. |
4 | Wang, L. H., and Wang, J. F. (2001) Determination of retinoids in human serum, tocopherol and retinyl acetate in pharmaceuticals by RP-HPLC with electrochemical detection. J. Pharm. Biomed. Anal. 25, 785-793. DOI ScienceOn |
5 | Warner, K., and Mounts, T. L. (1990) Analysis of tocopherols and phytosterols in vegetable oils by HPLC with evaporative light-scattering detection. J. Am. Oil Chem. Soc. 67, 827-831. DOI |
6 | KFDA (Korea Food and Drug Administration) (2009a) Food Standards Codes. Korean Foods Industry Association, Seoul, Korea. |
7 | KFDA (Korea Food and Drug Administration) (2009b) Food Standards Codes. Korean Foods Industry Association, Seoul, Korea, pp. 742-744. |
8 | KNS (The Korean Nutrition Society) (2001) Recommended dietary allowances for Koreans. 7th rev. The Korea Nutrition Society, Seoul, Korea. pp. 94-98. |
9 | Michael, T., Stephen, L. R. E., and Roger, W. (2002) Harmonized guidelines for single-laboratory validation of methods of analysis (IUPAC Technical Report). Pure Appl. Chem. 74, 835-855. DOI ScienceOn |
10 | Olivier, H., Marie, J. T., and Christopher, J. B. (2004) Simultaneous quantification of Vitamin A, D3 and E in fortified infant formulae by liquid chromatography-mass spectrometry. J. Chromatogr. A 1022, 115-123. DOI ScienceOn |
11 | Podda, M., Weber, C., Traber, M. G., and Packer, L. (1996) Simultaneous determination of tissue tocopherols, tocotrienols, ubiquinols, and ubiquinones. J. Lipid Res. 37, 893-901. |
12 | Qian, H. and Sheng, M. (1998) Simultaneous determination of fat-soluble vitamin A, D and E and pro-vitamin D2 in animal feeds by one-step extraction and high-performance liquid chromatography analysis. J. Chromatogr. A 825, 127-133. DOI ScienceOn |
13 | Chase, G. W. and Long, A. R. (1998) Liquid chromatographic method for analysis of all-rac-alpha-tocopheryl acetate and retinyl palmitate in milk-based infant formula using matrix solid-phase dispersion. J. AOAC Int. 81, 582-586. |
14 | Rodas, M. B., Morera, P. S., Castellote B. A. I., and Lopez- Sabater, M. C. (2003) Rapid determination by revesed-phase high-performance liquid chromatography of vitamins A and E in infant formulas. J. Chromatogr. A 1018, 197-202. DOI ScienceOn |
15 | Soledad, A. H., Sonia, N. R., M Teresa, V. N., and Abel, M. F. (1997) Determination of vitamins A and E in infant milk formula by high-performance liquid chromatography. J. Chromatogr. A 778, 243-247. DOI ScienceOn |
16 | Chase, G. W., Akoh, C. C., and Eitenmiller, R. R. (1994) Analysis of tocopherols in vegetable oils by high-performance liquid chromatography: comparison of fluorescence and evaporative light-scattering detection. J. Am. Oil Chem. Soc. 71, 877-880. DOI |
17 | Codex (2007) Standard for infant formula and formulas for special medical purposes intended for infants. Codex Stan. 72-1981. |
18 | Daood, H. G., Korbasz, M., and Hamdan, S. (2008) Simulatneous HPLC determination of Ergosterol, Tocopherols and Cartenoids in foods. Chromatographia 68, S137-S140. DOI |
19 | ICH (International Conference on Harmonization of Technical) Expert Working Group (2005) ICH Harmonized tripartite guideline validation of analytical procedures : text and methodology Q2(R1). Step 4:1-18. |
20 | Jonathan, W. D. and Karlene, R. S. (2002) Determination of vitamin A (Retinol) and vitamin E (alpha-tocopherol) in foods by liquid chromatography. Collaborative. J. AOAC Int. 85, 424-434. |
21 | CEN (European Committee for Standardization) (2000b) Foodstuffs-Determination of vitamin E by HPLC. Measurement of alpha-, beta-, gamma-, and delta-tocopherol. BS EN 12822. |
22 | Jorge, L., Chavez, S., Ana, I. C., and M. Carmen, L. S. (2006) Simultaneous analysis of vitamin A and E in infant milk-based formulae by normal-phase high performance chromatography-diode array detection using a short narrowbore column. J. Chromatogr. A 1122, 138-143. DOI ScienceOn |
23 | Jorge, L., Chavez, S., Ana, I. C., and M. Carmen, L. S. (2008) Vitamins A and E content in infant milk-based powered formulae after opening the packet. Food Chem. 106, 299-309. DOI ScienceOn |
24 | Kamal-Eldin, A., Gorgen, S., Pettersson, J., and Lampi, A. M. (2000) Normal-phase high-performance liquid chromatography of tocopherols and tocotrienols. Comparison of different chromatographic columns. J. Chromatogr. A 881, 217-227. DOI ScienceOn |
25 | AOAC (2005) Official Methods of Analysis. 18th ed, Association of Official Analytical Chemists, Gaithersburg, MA, USA, Ch 50, pp. 4-5. |
26 | CEN (European Committee for Standardization) (2000a) Foodstuffs-Determination of vitamin A by HPLC. Part I. Measurement of all-trans-retinol and 13-cis-retinol. BS EN 12823-1. |
![]() |