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http://dx.doi.org/10.5851/kosfa.2008.28.4.431

Neuroprotective Effects and Physicochemical Characteristics of Milk Fortified with Fibroin BF-7  

Choi, Gooi-Hun (Division of Animal Life Science, Konkuk University)
Jo, Mi-Na (Division of Animal Life Science, Konkuk University)
Moon, Sun-Hee (Division of Animal Life Science, Konkuk University)
Lim, Sung-Min (Division of Animal Life Science, Konkuk University)
Jung, A-Ram (Division of Animal Life Science, Konkuk University)
Yoon, Yoh-Chang (Division of Animal Life Science, Konkuk University)
Paik, Hyun-Dong (Division of Animal Life Science, Konkuk University)
Publication Information
Food Science of Animal Resources / v.28, no.4, 2008 , pp. 431-436 More about this Journal
Abstract
The impact of storage on the neuroprotective effects against $A\beta$-induced cell death and physicochemical characteristics of milk fortified with BF-7 were investigated. The BF-7 milk exerted protection of neuronal cells SK-N-SH from amyloid beta ($A\beta$)-induced neuronal stress. Our results showed that incubation of the cell with pretreated BF-7 milk, significantly attenuated apoptotic stress by $A\beta$, considered in cell morphology and nucleus shape. The general compositions were maintained consistently in BF-7 fortified milk (BF-7 milk). The BF-7 did not make any disturbance on pH and titratable acidity. The color change was not detected, either. Also, any microorganism had not been detected with more than 7 days storage at $4^{\circ}C$. In sensory evaluation study. the average scores of each sensory attribute were quite similar with plain milk. In conclusion, our results strongly indicate that BF-7 characteristics are quite adequate to be included in milk and BF-7 milk is still working well on neuro-protection, result in enforcing our brain and delaying neurodegeneration.
Keywords
BF-7; nutraceutical substance; milk; neuroprotective effect; amyloid $\beta$-peptide;
Citations & Related Records
Times Cited By KSCI : 4  (Citation Analysis)
Times Cited By Web Of Science : 2  (Related Records In Web of Science)
Times Cited By SCOPUS : 2
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