In this study, Ant Colony Algorithm(ACO) was used for optimal model. ACO which are metaheuristic algorithm for combinatorial optimization problem are inspired by the fact that ants are able to find the shortest route between their nest and food source. For applying the model to water distribution systems, pipes, tanks(reservoirs), pump construction and pump operation cost were considered as object function and pressure at each node and reservoir level were considered as constraints. Modified model from Ostfeld and Tubaltzev(2008) was verified by applying 2-Looped, Hanoi and Ostfeld's networks. And sensitivity analysis about ant number, number of ants in a best group and pheromone decrease rate was accomplished. After the verification, it was applied to real water network from S water treatment plant. As a result of the analysis, in the Two-looped network, the best design cost was found to $419,000 and in the Hanoi network, the best design cost was calculated to $6,164,384, and in the Ostfeld's network, the best design cost was found to $3,525,096. These are almost equal or better result compared with previous researches. Last, the cost of optimal design for real network, was found for 66 billion dollar that is 8.8 % lower than before. In addition, optimal diameter for aged pipes was found in this study and the 5 of 8 aged pipes were changed the diameter. Through this result, pipe construction cost reduction was found to 11 percent lower than before. And to conclusion, The least cost design model on water distribution system was developed and verified successfully in this study and it will be very useful not only optimal pipe change plan but optimization plan for whole water distribution system.