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Whitening improvement effect of Hermetia illucens larvae extracts

아메리카동애등에(Hermetia illucens) 유충 추출물의 미백개선 효과

  • Park, Ji Yeong (Industrial Insect and Sericulture Division, Department of Agricultural Biology, National Institute of Agricultural Sciences, RDA) ;
  • Kim, Sun Young (Industrial Insect and Sericulture Division, Department of Agricultural Biology, National Institute of Agricultural Sciences, RDA) ;
  • Koo, Bonwoo (Industrial Insect and Sericulture Division, Department of Agricultural Biology, National Institute of Agricultural Sciences, RDA) ;
  • Kim, Eunsun (Industrial Insect and Sericulture Division, Department of Agricultural Biology, National Institute of Agricultural Sciences, RDA) ;
  • Kim, Yong-Soon (Industrial Insect and Sericulture Division, Department of Agricultural Biology, National Institute of Agricultural Sciences, RDA) ;
  • Park, Kwanho (Industrial Insect and Sericulture Division, Department of Agricultural Biology, National Institute of Agricultural Sciences, RDA)
  • 박지영 (농촌진흥청 국립농업과학원 농업생물부 곤충양잠산업과) ;
  • 김선영 (농촌진흥청 국립농업과학원 농업생물부 곤충양잠산업과) ;
  • 구본우 (농촌진흥청 국립농업과학원 농업생물부 곤충양잠산업과) ;
  • 김은선 (농촌진흥청 국립농업과학원 농업생물부 곤충양잠산업과) ;
  • 김용순 (농촌진흥청 국립농업과학원 농업생물부 곤충양잠산업과) ;
  • 박관호 (농촌진흥청 국립농업과학원 농업생물부 곤충양잠산업과)
  • Received : 2022.09.21
  • Accepted : 2022.10.11
  • Published : 2022.10.31

Abstract

The present study investigated the feasibility of using the ethanolic extract of Hermetia illucens larvae (HIE) as a whitening improvement material. In cell viability assays using B16F1 melanoma cells, no cytotoxicity was recorded up to 200 ㎍·mL-1 of HIE. Moreover, while tyrosinase inhibitory activity increased, melanin content decreased in a dose-dependent manner, indicating that HIE likely inhibited tyrosine-induced intracellular melanin biosynthesis in B16F1 melanoma cells. Therefore, HIE is expected to serve as a potent whitening improvement material.

Keywords

Acknowledgement

본 연구는 농촌진흥청 연구사업(연구개발과제명: 동애등에를 이용한 사료원료 개발, PJ015092)의 지원에 의해 이루어진 것입니다.

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