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http://dx.doi.org/10.5322/JESI.2022.31.10.883

Whitening improvement effect of Hermetia illucens larvae extracts  

Park, Ji Yeong (Industrial Insect and Sericulture Division, Department of Agricultural Biology, National Institute of Agricultural Sciences, RDA)
Kim, Sun Young (Industrial Insect and Sericulture Division, Department of Agricultural Biology, National Institute of Agricultural Sciences, RDA)
Koo, Bonwoo (Industrial Insect and Sericulture Division, Department of Agricultural Biology, National Institute of Agricultural Sciences, RDA)
Kim, Eunsun (Industrial Insect and Sericulture Division, Department of Agricultural Biology, National Institute of Agricultural Sciences, RDA)
Kim, Yong-Soon (Industrial Insect and Sericulture Division, Department of Agricultural Biology, National Institute of Agricultural Sciences, RDA)
Park, Kwanho (Industrial Insect and Sericulture Division, Department of Agricultural Biology, National Institute of Agricultural Sciences, RDA)
Publication Information
Journal of Environmental Science International / v.31, no.10, 2022 , pp. 883-890 More about this Journal
Abstract
The present study investigated the feasibility of using the ethanolic extract of Hermetia illucens larvae (HIE) as a whitening improvement material. In cell viability assays using B16F1 melanoma cells, no cytotoxicity was recorded up to 200 ㎍·mL-1 of HIE. Moreover, while tyrosinase inhibitory activity increased, melanin content decreased in a dose-dependent manner, indicating that HIE likely inhibited tyrosine-induced intracellular melanin biosynthesis in B16F1 melanoma cells. Therefore, HIE is expected to serve as a potent whitening improvement material.
Keywords
Hermetia illucens; Whitening; Tyrosinase inhibitory activity; Melanin content;
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1 Alvarez, D., Wikinson, K. A., Treihou, M., Tene, N., Castillo, D., Sauvain, M. 2019. Prospecting peptides isolated from black soldier fly (Diptera: stratiomyidae) with antimicrobial activity against Helicobacter pylori (Campylobacterales: Helicobacteraceae), J. Insect Sci., 19, 1-5.
2 Berneburg, M., Plettenberg, H., Krutmann, J., 2000, Photoaging of human skin, Photodermatol. Photoimmunol. Photomed. 16, 239-244.   DOI
3 Ali, M. F. Z., Ohta, T., Ido, A., Miura, C., Miura, T., 2019, The dipterose of black soldier fly (Hermetia illucens) induces innate immune response through Toll-like receptor pathway in mouse macrophage RAW264.7 cells, Biomolecules 9, E677.
4 Carmichael, J., DeGraff, W. G., Gazdar, A. F., Minna, J. D., Mitchell, H. B., 1987, Evaluation of a tetrazolium based semiautomated colorimetric assay: assessment of chemosensitivity testing, Cancer Res., 47, 936-942.
5 Choi, I. H., Park, K. H., Shoi, S. U., Jung, Y. W., Kim, S., Park, C. Y., Chung, T. H., 2022, Effects of dietary Ptecticustenebrifier on the fecal microbiomes of Bichon fries, J. Environ. Sci. Int., 31, 535-542.   DOI
6 delMarmol, V., Beermann, F., 1996, Tyrosinase and related proteins in mammalian pigmentation, FEBS Lett. 381, 165-168.   DOI
7 Jeon, M., Lee, K. M., Lim, Y. H., Kim, J. K., 2009, Rhapontigenin production by bioconversion and inhibition of melanin synthesis, Kor. J. Microbiol. Biotechnol., 37, 49-54.
8 Jo, J. B., Kim, M. U., Lee, E. H., Kim, Y. J., Cho, E. B., Kang, I. K., Cho, Y. J., 2018, Whitening effect of extracts from MatricariachamomillaL. with B16F10 melanoma cells, J. Appl. Biol. Chem., 61, 267-273.
9 Kameyama, K., Jimenez, M., Muller, J., Ishida, Y., Hearing, V. J., 1989, Regulation of mammalian melanogenesis by tyrosinase inhibition, Differentiation, 42, 28-36.   DOI
10 Kim, J. E., Kim, D. I., Koo, H. Y., Kim, H. J., Kim, S. Y., Lee, Y. B., moon, J. H., Choi, Y. S., 2020, Pupal drone extracts for anti-wrinkle and skin-lightening materials, J. Life Sci., 30, 428-433.
11 Lerner, A. B., Fitzpatrick, T. B., 1950, Biochemistry of melanin formation, Physiol. Rev., 30,91-126.   DOI
12 Kim, I. W., Lee, J. H., Kwon, Y. N., Kim, S. H., Yun, E. Y., Nam, S. H., Ahn, M. Y., Hwang, J. S., 2014, Inhibitory effect of melanin synthesis using organic solvent extracts from Scolopendrasubspinipesmutilans, J. Seric. Entomol. Sci., 52, 1-5.
13 Yagi, A., Kanbara, T., Morinobu, N., 1987, Inhibition of mushroom-tyrosinase by aloe extract, Planta Med., 53, 515-517.   DOI
14 Nguyen, D. H., Nguyen, D. T. M., La, L. H., Yang, S. H., Lee, H. B., Kim, R. J., Shin, J. H., Kim, D. M., Kim,E. K., 2007, Depigmenting effect of Cinnamomum cassia Presl in B16F10 melanoma cells, Korean J. Chem. Eng., 24, 827.   DOI
15 Choung, M. G., Hwang, Y. S., Kim, G. P., Ahn, K. G., Shim, H. S., Hong, S. B., Choi, J. H., Yu, C. Y., Chong, I. M., Kim, S. H., Lim, J. D., 2013, Antimelanogenic effect and whitening of anthocyanin rich fraction from seeds of Liriopeplatyphylla, Korean J. Medicinal Crop Sci., 21, 361-371.   DOI
16 Choi, I. H., Shoi, S. U., Jeong, Y. W., Park, K. H., Kim, T. H., Park, K. W., Chung, T. H., 2022, Effects of dietary Ptecticutenebrifer powder and canned mixtures on protein digestibility by different breeds of companion dogs, J. Environ. Sci. Int., 31, 285-289.   DOI
17 Jimenez-Cervantes, C., Solano, F., Kobayashi, T., Urabe, K., Hearing, V. J., Lozano, J. A., Garcia-Borron, J. C., 1994, A New enzymatic function in the melanogenic pathway. The 5, 6-dihydroxyindole-2-carboxylic acid oxidase activity of tyrosinase-related protein-1 (TRP1), J. Biol Chem., 269,17993-18000.   DOI
18 Park, J. Y., Kwak, K. W., Choi, J. Y., Lee, S. E., Kim, Y. S., Koo B., Kim E., Park, K., Kim, S. Y., 2021, Ethanol extract of Hermetiaillucens larvae inhibits adipogenesis in 3T3-L1 adipocytes, J. Life Sci., 31, 1094-1099.
19 Park, H. Y., Kosmadaki, M., Yaar, M., Gilchrest, B. A., 2009, Cellular mechanisms regulating human melanogenesis, Cell Mol. Life Sci.,66,1493-1506.   DOI
20 Sanchez, F. A., Rodriguez, L. J. N., Garcia, C. F., Garcia, C. F., 1995, Tyrosinase a comprehensive review of its mechanism, J. Biochim. Biophys. Acta.,1247, 1-11.   DOI
21 Park, K., Choi, J., Nam, S., Kim, S., Kwak, K., Lee, S., Nho, S., 2014, Antioxidant activities of black soldier fly, Hermetiaillucens, J. Seric. Entomol. Sci., 52, 142-146.
22 Ushakova, N., Dontsov, A., Sakina, N., Bastrakov, A., Ostrovsky, M., 2019, Antioxidative properties of melanins and ommochromes from black soldier fly Hermetiaillucens. Biomolecules 9, E408.
23 Yoon, M. Y., 2016, A Study on peanut spouts extract as the anti-oxidant activity and the skin whitening cosmetic ingredients, KSBB. J.31, 14-19.   DOI
24 Yoon, Y. C., Kim, B. H., Kim, J. K., Lee, J. H., Park, Y. E., Kwon, G. S., Hwang, H. S., Lee, J. B., 2018, Verification of biological activities and tyrosinase inhibition of ethanol extracts from Hemp Seed (Cannabis sativa L.) fermented with lactic acid bacteria, J. Life Sci., 28, 688-696.
25 You, S. H., 2017, Antioxidant activity and whitening activity of Psidiumguajava leaf extract, J. Oil Appl. Sci., 34, 296-304.
26 Masamoto, Y., Ando, H., Murata, Y., Shimoishi, Y., Tada, M., Takahata, K., 2003, Mushroom tyrosinase inhibitory activity of esculetin isolated from seeds of Euphorbia lathyrisL, Biosci. Biotechnol.Biochem.67, 631-634.   DOI
27 Park, J. G., Karmer, B. S., Steinberg, S. M., Carmichael, J., Collins, J. M., Minna, J. D., Gazdar, A. F., 1987, Chemosensitivity testing of human colorectal carcinoma cell lines using a tetrazolium-based colorimetric assay, Cancer Res. 47, 5875-5879.
28 Pyo, S. J., Won, J., Kang D. G., Sohn, H. Y., 2020, Antithrombotic activity of Hermetiaillucens (Black soldier fly), J. Life Sci., 30, 386-393.