과제정보
This work was supported by National Research Foundation of Korea (NRF) grants NRF-2017M3A9G7073086, NRF-2021R1A2C3005603, NRF-2020R1A5A2017323, NRF-2022R1A2C1008591, and NRF-2021R1C1C2003405, funded by the Ministry of Science and ICT.
참고문헌
- Cohen M, Lippman M and Chabner B (1978) Role of pineal gland in aetiology and treatment of breast cancer. Lancet 2, 814-816 https://doi.org/10.1016/S0140-6736(78)92591-6
- Jung B and Ahmad N (2006) Melatonin in cancer management: progress and promise. Cancer Res 66, 9789-9793 https://doi.org/10.1158/0008-5472.CAN-06-1776
- Mehrzadi S, Pourhanifeh MH, Mirzaei A, Moradian F and Hosseinzadeh A (2021) An updated review of mechanistic potentials of melatonin against cancer: pivotal roles in angiogenesis, apoptosis, autophagy, endoplasmic reticulum stress and oxidative stress. Cancer Cell Int 21, 188
- Sarti P, Magnifico MC, Altieri F, Mastronicola D and Arese M (2013) New evidence for cross talk between melatonin and mitochondria mediated by a circadian-compatible interaction with nitric oxide. Int J Mol Sci 14, 11259-11276 https://doi.org/10.3390/ijms140611259
- Lee S, Byun JK, Park M et al (2020) Melatonin inhibits vascular smooth muscle cell proliferation and apoptosis through upregulation of Sestrin2. Exp Ther Med 19, 3454-3460
- Fernandez-Gil BI, Guerra-Librero A, Shen YQ et al (2019) Melatonin enhances cisplatin and radiation cytotoxicity in head and neck squamous cell carcinoma by stimulating mitochondrial ros generation, apoptosis, and autophagy. Oxid Med Cell Longev 2019, 7187128
- Luchetti F, Canonico B, Betti M et al (2010) Melatonin signaling and cell protection function. Faseb j 24, 3603-3624 https://doi.org/10.1096/fj.10-154450
- DeBerardinis RJ, Lum JJ, Hatzivassiliou G and Thompson CB (2008) The biology of cancer: metabolic reprogramming fuels cell growth and proliferation. Cell Metab 7, 11-20 https://doi.org/10.1016/j.cmet.2007.10.002
- Yecies JL and Manning BD (2011) Transcriptional control of cellular metabolism by mTOR signaling. Cancer Res 71, 2815-2820 https://doi.org/10.1158/0008-5472.CAN-10-4158
- Salmond RJ (2018) mTOR regulation of glycolytic metabolism in T cells. Front Cell Dev Biol 6, 122
- Hevia D, Gonzalez-Menendez P, Fernandez-Fernandez M, Cueto S and Rodriguez-Gonzalez P (2017) Melatonin decreases glucose metabolism in prostate cancer cells: A (13)C stable isotope-resolved metabolomic study. Int J Mol Sci 18, 162
- Li ZY, Yang Y, Ming M and Liu B (2011) Mitochondrial ROS generation for regulation of autophagic pathways in cancer. Biochem Biophys Res Commun 414, 5-8 https://doi.org/10.1016/j.bbrc.2011.09.046
- Csibi A, Lee G, Yoon SO et al (2014) The mTORC1/S6K1 pathway regulates glutamine metabolism through the eIF4B-dependent control of c-Myc translation. Curr Biol 24, 2274-2280 https://doi.org/10.1016/j.cub.2014.08.007
- Park SY, Jang WJ, Yi EY et al (2010) Melatonin suppresses tumor angiogenesis by inhibiting HIF-1alpha stabilization under hypoxia. J Pineal Res 48, 178-184 https://doi.org/10.1111/j.1600-079X.2009.00742.x
- Park JW, Hwang MS, Suh SI and Baek WK (2009) Melatonin down-regulates HIF-1 alpha expression through inhibition of protein translation in prostate cancer cells. J Pineal Res 46, 415-421 https://doi.org/10.1111/j.1600-079X.2009.00678.x
- Bonello S, Zahringer C, BelAiba RS et al (2007) Reactive oxygen species activate the HIF-1alpha promoter via a functional NFkappaB site. Arterioscler Thromb Vasc Biol 27, 755-761 https://doi.org/10.1161/01.ATV.0000258979.92828.bc
- Loureiro R, Magalhaes-Novais S, Mesquita KA et al (2015) Melatonin antiproliferative effects require active mitochondrial function in embryonal carcinoma cells. Oncotarget 6, 17081-17096 https://doi.org/10.18632/oncotarget.4012
- Gonzalez A, Estaras M, Martinez-Morcillo S and Martinez R (2020) Melatonin modulates red-ox state and decreases viability of rat pancreatic stellate cells. Sci Rep 10, 6352
- Guo C, Sun L, Chen X and Zhang D (2013) Oxidative stress, mitochondrial damage and neurodegenerative diseases. Neural Regen Res 8, 2003-2014
- Ni HM, Williams JA, Jaeschke H and Ding WX (2013) Zonated induction of autophagy and mitochondrial spheroids limits acetaminophen-induced necrosis in the liver. Redox Biol 1, 427-432 https://doi.org/10.1016/j.redox.2013.08.005
- Ben-Sahra I and Manning BD (2017) mTORC1 signaling and the metabolic control of cell growth. Curr Opin Cell Biol 45, 72-82 https://doi.org/10.1016/j.ceb.2017.02.012
- Ferreira GM, Martinez M, Camargo IC, Domeniconi RF, Martinez FE and Chuffa LG (2014) Melatonin attenuates Her-2, p38 MAPK, p-AKT, and mTOR levels in ovarian carcinoma of ethanol-preferring rats. J Cancer 5, 728-735 https://doi.org/10.7150/jca.10196