Journal of Radiopharmaceuticals and Molecular Probes (대한방사성의약품학회지)

Korean Society of Radiopharmaceuticals and Molecular Probes (대한방사성의약품학회)
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Challenge of 2-dimensional Inorganic Nanoparticles in Nuclear Medicine

  • Sairan Eom (Division of Applied-RI, Korea Institute of Radiological and Medical Sciences (KIRAMS)) ;
  • Jin-Ho Choy (Intelligent Nanohybrid Materials Laboratory (INML), Institute of Tissue Regeneration Engineering (ITREN), Dankook University) ;
  • Kyo Chul Lee (Division of Applied-RI, Korea Institute of Radiological and Medical Sciences (KIRAMS)) ;
  • Yong Jin Lee (Division of Applied-RI, Korea Institute of Radiological and Medical Sciences (KIRAMS))
  • Received : 2022.11.17
  • Accepted : 2022.12.08
  • Published : 2022.12.30
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Abstract

2-Dimensional inorganic nanoparticles with high surface area and ion-exchangeable properties have been continuously growing based on nanotechnology in the field of nanomedicine. Among one of the 2-D nanoparticles, layered double hydroxide (LDH) has been intensively explored as drug delivery due to its low toxicity, enhanced cellular permeability, and high drug loading capacity. Moreover, controllable chemical composition makes possible varying isomorphic layered materials for therapy and imaging of diseases. In this review, specific structural characteristics of LDH were introduced, and its potential for application as a biocompatible therapeutic agent and diagnostic one was addressed in nuclear medicine, one of promising fields in nanomedicine.

Keywords

Acknowledgement

This study was supported by a grant from the Korea Institute of Radiological and Medical Sciences (KIRAMS), by the Ministry of Science and ICT (MSIT), the Republic of Korea (No. 50536-2022). This work was supported by the National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIT) (No. 2022R1C1C2012275).

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