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http://dx.doi.org/10.22643/JRMP.20228.2.119

Challenge of 2-dimensional Inorganic Nanoparticles in Nuclear Medicine  

Sairan Eom (Division of Applied-RI, Korea Institute of Radiological and Medical Sciences (KIRAMS))
Jin-Ho Choy (Intelligent Nanohybrid Materials Laboratory (INML), Institute of Tissue Regeneration Engineering (ITREN), Dankook University)
Kyo Chul Lee (Division of Applied-RI, Korea Institute of Radiological and Medical Sciences (KIRAMS))
Yong Jin Lee (Division of Applied-RI, Korea Institute of Radiological and Medical Sciences (KIRAMS))
Publication Information
Journal of Radiopharmaceuticals and Molecular Probes / v.8, no.2, 2022 , pp. 119-128 More about this Journal
Abstract
2-Dimensional inorganic nanoparticles with high surface area and ion-exchangeable properties have been continuously growing based on nanotechnology in the field of nanomedicine. Among one of the 2-D nanoparticles, layered double hydroxide (LDH) has been intensively explored as drug delivery due to its low toxicity, enhanced cellular permeability, and high drug loading capacity. Moreover, controllable chemical composition makes possible varying isomorphic layered materials for therapy and imaging of diseases. In this review, specific structural characteristics of LDH were introduced, and its potential for application as a biocompatible therapeutic agent and diagnostic one was addressed in nuclear medicine, one of promising fields in nanomedicine.
Keywords
2-Dimensional inorganic nanoparticle; Layered double hydroxide; Nuclear medicine;
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