The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology (한방안이비인후피부과학회지)

The Society of Korean Medicine Ophthalmology, Otolaryngology & Dermatology (대한한방안이비인후피부과학회)
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A Study on The Manufacturing Method, Formulation and Toxicity for Clinical Use of Topical Agents in Geumgweyoryak

《금궤요략(金匱要略)》 외용제의 임상활용을 위한 제법, 제형 및 독성에 대한 고찰

  • You, Jae-Hyun (Department of Clinical Korean Medicine (Ophthalmology, Otolaryngology and Dermatology of Korean Medicine), Graduate School of Korean Medicine, Kyung Hee University) ;
  • Kim, Kyuseok (Department of Ophthalmology, Otolaryngology and Dermatology of Korean Medicine, College of Korean Medicine, Kyung Hee University)
  • 유재현 (경희대학교 한의과대학원 임상한의학과) ;
  • 김규석 (경희대학교 한의과대학 한방안이비인후피부과 교실)
  • Received : 2022.01.04
  • Accepted : 2022.02.10
  • Published : 2022.02.25
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Abstract

Objectives : The purpose of this literature review is to analyze process of manufacture and formulation and toxicity of Geumgweyoryak(金匱要略)'s external applicants for modern and safe using. Methods : This study used the Geumgweyoryak(金匱要略) reprinted by Zhao Kaimei(趙開美) as basic data for a understanding of the manufacture and formulation and toxicity for external applicants. Among the 25 chapters, the 22 chapters were studied except for the last three chapters, which are known to be written by later writers. Based on the above, Geumgweyoryeok(金匱要略)'s external applicants was analyzed the process of manufacture, formulation and the toxicity. Results : There are 11 types of external applicants of Geumgweyoryak(金匱要略). Washing method(洗法) was used 2 times, Drop method(瀝法) was used 1 time, Smoke method(熏法) was used 2 times, Rubbing method(摩法) was used 1 time, Plaster method(敷法) was used 2 times, Invading method(浸法) was used 1 time, Suppository method (坐法) was used 2 times, Flatiron method(烙法) was used 1 time. According to classified the modern formulation, there are 4 types of powder formulation, 4 types of liquid formulation, 2 types of suppository, and 1 type of Semi-solid formulation. Especially toxic drugs, such as Realgar(雄黃) or Hydrocerussite(鉛粉), should be careful. When Realgar(雄黃) smokes, a toxic substance called AS2O3 can come out. Hydrocerussite(鉛粉) can cause lead poisoning. Lead increases the risk of anemia, dehydration, and lead neuropathy when chronically exposed. Conclusion : We supposed that this study can serve as a basic data to help clinical Korean doctors to use the prescription for external applicants more safely and to easily apply it in the form of external applicants.

Keywords

References

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