한국식품영양학회지 (The Korean Journal of Food And Nutrition)

  • 제34권5호
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  • Pages.553-559
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  • 2021
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  • 1225-4339(pISSN)
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  • 2287-4992(eISSN)
한국식품영양학회 (The Korean Society of Food and Nutrition)
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박달나무로부터 분리된 페놀성 화합물의 항산화 및 Tyrosinase 저해 활성 연구

Identification of Anti-Oxidant and Anti-Tyrosinase Activity of Phenolic Components Isolated from Betula schmidtii

  • 왕다혜 (덕성여자대학교 자연과학대학 화학과) ;
  • 정하숙 (덕성여자대학교 자연과학대학 식품영양학과)
  • Wang, Da-Hye (Dept. of Chemistry, College of Natural Sciences, Duksung Women's University) ;
  • Chung, Ha Sook (Dept. of Food and Nutrition, College of Natural Sciences, Duksung Women's University)
  • 투고 : 2021.08.09
  • 심사 : 2021.10.14
  • 발행 : 2021.10.31
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초록

The aim of study to investigate the phytochemicals and biological activities the bark of Betula schmidtii. The studies consisted of the solvent extraction, followed by the isolation of phenolic components 1~3 from ethyl acetate-soluble fraction of Betula schmidtii Bark. Their chemical structures were identified as arbutin (1), ρ-coumaric acid (2) and ferulic acid (3) using Ultraviolet-Visible (UV-Vis) Spectrophotometer, Electrospray Ionization Mass Spectrometry (ESI-MS) (negative ion mode), 1H-Nuclear Magnetic Resonance (NMR), 13C-NMR, 1H-1H Correlation Spectroscopy (COSY) and 1H-13C Hetero Nuclear Multiple Quantum Correlation (HMQC) spectral data. Compounds 1~3 shows the anti-oxidant effect with IC50 values of 29.74±1.52, 21.32±1.07 and 34.41±1.24 in 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging activity, respectively. Also, compounds 1~3 exhibited mushroom tyrosinase inhibitory activity with IC50 values of 31.14±1.07, 42.54±1.46 and 69.22±1.43 µM, respectively.

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