대한한방내과학회지 (The Journal of Internal Korean Medicine)

대한한방내과학회 (The Society of Internal Korean Medicine)
권호 표지
DOI QR코드

DOI QR Code

기존의 경구용 혈당강하제로 혈당조절이 불량한 제2형 당뇨병 환자에 대한 한양방 병용 치료 1례

A Case Report of Add-On Traditional Korean Medical Treatments in a Patient with Uncontrolled Type 2 Diabetes Mellitus with Conventional Oral Hypoglycemic Agents

  • 이혜윤 (부산대학교 한의학전문대학원) ;
  • 정은선 (대전대학교 한의과대학 심계내과학교실) ;
  • 윤영주 (부산대학교 한의학전문대학원) ;
  • 이상엽 (양산부산대학교병원 가정의학과 및 의생명연구소, 부산대학교 의과대학 의학교육학교실 및 천연물 및 기능성식품 통합연구소)
  • Lee, Hye-Yoon (School of Korean Medicine, Pusan National University) ;
  • Jung, Eun-sun (Dept. of Circulatory Internal Medicine, College of Korean Medicine, Daejeon University) ;
  • Yun, Youngju (School of Korean Medicine, Pusan National University) ;
  • Lee, Sang Yeoup (Dept. of Family Medicine and Biomedical Research Institute, Pusan National University Yangsan Hospital, Dept. of Medical Education, Pusan National University School of Medicine, and Integrated Research Institute for Natural Ingredients and Functional Foods)
  • 투고 : 2021.08.28
  • 심사 : 2021.10.04
  • 발행 : 2021.09.30
PDF 다운로드
⟨ 이전 논문 다음 논문 ⟩

초록

This study presents a case of add-on traditional Korean medical treatments in a 77-year-old male patient with uncontrolled type 2 diabetes mellitus with conventional oral hypoglycemic agents. Chief complaints were uncontrolled glucose level and weight loss. The patient was treated with electroacupuncture (on ST36, CV4, and CV12), herbal medication, and lifestyle advice. The conventional oral hypoglycemic medications were maintained. After 12 weeks, the glycated hemoglobin A1c (HbA1c) decreased from 11.0% to 8.4%. There were significant abnormalities in the liver function and renal function tests, but no adverse event was reported. Further studies are needed to confirm the findings of this case.

키워드

참고문헌

  1. 2019 국민건강통계; 보건복지부, 질병관리본부(국가승인통계 제117002호, 국민건강영양조사). Updated April 1, 2021. Accessed August 20, 2021. https://www.index.go.kr/potal/main/EachDtlPageDetail.do?idx_cd=1438
  2. American Diabetes Association. 8. Pharmacologic approaches to glycemic treatment: standards of medical care in diabetes-2018. Diabetes Care 2018;41(Supplement 1):S73-85. https://doi.org/10.2337/dc18-S008
  3. Commitee of Clinical Practice Guideline. Treatment guideline for diabetes. Seoul: Korean diabetes association; 2015.
  4. Kim YH, Chae US. 소갈(消渴)의 병인병기(病因病機)와 침구치료(鍼灸治療)에 관(關)한 문헌적(文獻的) 고찰(考察). Journal of Haehwa Medicine 1995;4(1):269-85.
  5. Son A, Koh J, Lee D, Shin H. Review of domestic experimental studies of Korean medicine treatment for diabetes mellitus since 2013. The Journal of Internal Korean Medicine 2017;38(1):10-19. https://doi.org/10.22246/jikm.2017.38.1.10
  6. Chang CL, Lin Y, Bartolome AP, Chen Y, Chiu S, Yang W. Herbal therapies for type 2 diabetes mellitus: chemistry, biology, and potential application of selected plants and compounds. Evidence-Based Complementary and Alternative Medicine 2013;2013:378657. https://doi.org/10.1155/2013/378657
  7. Choudhury H, Pandey M, Hua CK, Mun CS, Jing JK, Kong L, et al. An update on natural compounds in the remedy of diabetes mellitus: A systematic review. Journal of traditional and complementary medicine 2018;8(3):361-76. https://doi.org/10.1016/j.jtcme.2017.08.012
  8. Cho SI, Son MW, Hong KE. Glycemic control effects of Sanyak (Dioscoreae rhizoma) extract in prediabetic stage patients. The Journal of Korean Medicine 2010;31(5):146-66.
  9. Chen C, Liu J, Sun M, Liu W, Han J, Wang H. Acupuncture for type 2 diabetes mellitus: A systematic review and meta-analysis of randomized controlled trials. Complementary therapies in clinical practice 2019;36:100-12. https://doi.org/10.1016/j.ctcp.2019.04.004
  10. Lin R, Tzeng CY, Lee YC, Ho WJ, Cheng JT, Lin JG, et al. Acute effect of electroacupuncture at the Zusanli acupoints on decreasing insulin resistance as shown by lowering plasma free fatty acid levels in steroid-background male rats. journal article. BMC Complementary and Alternative Medicine 2009 August;9(1):26. doi:10.1186/1472-6882-9-26
  11. Liang F, Koya D. Acupuncture: is it effective for treatment of insulin resistance? Diabetes, obesity & metabolism 2010 Jul;12(7):555-69. doi:10.1111/j.1463-1326.2009.01192.x
  12. Committee of Clinical Practice Guideline. Clinical Practice Guidelines for Diabetes. Seoul: Korean diabetes association; 2021.
  13. 東醫寶鑑國譯委員會. 對譯 東醫寶鑑,. Seoul: Bubin Publishers; 1999, p. 1330-44.
  14. Daejeon University Korean Medicine Hospital. Korean Medicine Hospital Formulary. Daejeon University Korean Medicine Hospital; p. 208.
  15. Lo H, Li T, Yang T, Li C, Chiang J, Hsiang C, et al. Hypoglycemic effects of Trichosanthes kirilowii and its protein constituent in diabetic mice: the involvement of insulin receptor pathway. BMC Complementary and Alternative Medicine 2017;17(1):53. doi:10.1186/s12906-017-1578-6
  16. Li WL, Zheng HC, Bukuru J, De Kimpe N. Natural medicines used in the traditional Chinese medical system for therapy of diabetes mellitus. Journal of ethnopharmacology 2004 May;92(1):1-21. doi:10.1016/j.jep.2003.12.031
  17. Donnapee S, Li J, Yang X, Ge AH, Donkor PO, Gao X, et al. Cuscuta chinensis Lam.: A systematic review on ethnopharmacology, phytochemistry and pharmacology of an important traditional herbal medicine. Journal of ethnopharmacology 2014;157:292-308. https://doi.org/10.1016/j.jep.2014.09.032
  18. Korean Diabetes Assosiation. Treatment guideline for diabetes. Seoul; Korean Diabetes Assosiation;2015.
  19. Franz MJ, Powers MA, Leontos C, Holzmeister LA, Kulkarni K, Monk A, et al. The evidence for medical nutrition therapy for type 1 and type 2 diabetes in adults. Journal of the American Dietetic Association 2010;110(12): 1852-89. https://doi.org/10.1016/j.jada.2010.09.014
  20. Committee of Clinical Practice Guideline. Evidence-based Guideline for Type 2 Diabetes in Primary Care (2016). Seoul: Korean academy of medical sciences, Korea Centers for Disease Control and Prevention.
  21. Peyrot M, Rubin RR, Kruger DF, Travis LB. Correlates of insulin injection omission. Diabetes care 2010;33(2):240-5. https://doi.org/10.2337/dc09-1348
  22. Gu MO. Factors influencing glycemic control among type 2 diabetes mellitus patients: The Sixth Korea National Health and Nutrition Examination Survey (2013~2015). Korean Journal of Adult Nursing 2019;31(3):235-48. https://doi.org/10.7475/kjan.2019.31.3.235