Browse > Article
http://dx.doi.org/10.22246/jikm.2021.42.4.718

A Case Report of Add-On Traditional Korean Medical Treatments in a Patient with Uncontrolled Type 2 Diabetes Mellitus with Conventional Oral Hypoglycemic Agents  

Lee, Hye-Yoon (School of Korean Medicine, Pusan National University)
Jung, Eun-sun (Dept. of Circulatory Internal Medicine, College of Korean Medicine, Daejeon University)
Yun, Youngju (School of Korean Medicine, Pusan National University)
Lee, Sang Yeoup (Dept. of Family Medicine and Biomedical Research Institute, Pusan National University Yangsan Hospital, Dept. of Medical Education, Pusan National University School of Medicine, and Integrated Research Institute for Natural Ingredients and Functional Foods)
Publication Information
The Journal of Internal Korean Medicine / v.42, no.4, 2021 , pp. 718-726 More about this Journal
Abstract
This study presents a case of add-on traditional Korean medical treatments in a 77-year-old male patient with uncontrolled type 2 diabetes mellitus with conventional oral hypoglycemic agents. Chief complaints were uncontrolled glucose level and weight loss. The patient was treated with electroacupuncture (on ST36, CV4, and CV12), herbal medication, and lifestyle advice. The conventional oral hypoglycemic medications were maintained. After 12 weeks, the glycated hemoglobin A1c (HbA1c) decreased from 11.0% to 8.4%. There were significant abnormalities in the liver function and renal function tests, but no adverse event was reported. Further studies are needed to confirm the findings of this case.
Keywords
diabetes mellitus; traditional Korean medicine; herbal medicine; acupuncture; HbA1c;
Citations & Related Records
연도 인용수 순위
  • Reference
1 Choudhury H, Pandey M, Hua CK, Mun CS, Jing JK, Kong L, et al. An update on natural compounds in the remedy of diabetes mellitus: A systematic review. Journal of traditional and complementary medicine 2018;8(3):361-76.   DOI
2 Chen C, Liu J, Sun M, Liu W, Han J, Wang H. Acupuncture for type 2 diabetes mellitus: A systematic review and meta-analysis of randomized controlled trials. Complementary therapies in clinical practice 2019;36:100-12.   DOI
3 Lin R, Tzeng CY, Lee YC, Ho WJ, Cheng JT, Lin JG, et al. Acute effect of electroacupuncture at the Zusanli acupoints on decreasing insulin resistance as shown by lowering plasma free fatty acid levels in steroid-background male rats. journal article. BMC Complementary and Alternative Medicine 2009 August;9(1):26. doi:10.1186/1472-6882-9-26   DOI
4 Lo H, Li T, Yang T, Li C, Chiang J, Hsiang C, et al. Hypoglycemic effects of Trichosanthes kirilowii and its protein constituent in diabetic mice: the involvement of insulin receptor pathway. BMC Complementary and Alternative Medicine 2017;17(1):53. doi:10.1186/s12906-017-1578-6   DOI
5 Li WL, Zheng HC, Bukuru J, De Kimpe N. Natural medicines used in the traditional Chinese medical system for therapy of diabetes mellitus. Journal of ethnopharmacology 2004 May;92(1):1-21. doi:10.1016/j.jep.2003.12.031   DOI
6 Korean Diabetes Assosiation. Treatment guideline for diabetes. Seoul; Korean Diabetes Assosiation;2015.
7 Franz MJ, Powers MA, Leontos C, Holzmeister LA, Kulkarni K, Monk A, et al. The evidence for medical nutrition therapy for type 1 and type 2 diabetes in adults. Journal of the American Dietetic Association 2010;110(12): 1852-89.   DOI
8 Committee of Clinical Practice Guideline. Evidence-based Guideline for Type 2 Diabetes in Primary Care (2016). Seoul: Korean academy of medical sciences, Korea Centers for Disease Control and Prevention.
9 Peyrot M, Rubin RR, Kruger DF, Travis LB. Correlates of insulin injection omission. Diabetes care 2010;33(2):240-5.   DOI
10 Gu MO. Factors influencing glycemic control among type 2 diabetes mellitus patients: The Sixth Korea National Health and Nutrition Examination Survey (2013~2015). Korean Journal of Adult Nursing 2019;31(3):235-48.   DOI
11 東醫寶鑑國譯委員會. 對譯 東醫寶鑑,. Seoul: Bubin Publishers; 1999, p. 1330-44.
12 Committee of Clinical Practice Guideline. Clinical Practice Guidelines for Diabetes. Seoul: Korean diabetes association; 2021.
13 American Diabetes Association. 8. Pharmacologic approaches to glycemic treatment: standards of medical care in diabetes-2018. Diabetes Care 2018;41(Supplement 1):S73-85.   DOI
14 Son A, Koh J, Lee D, Shin H. Review of domestic experimental studies of Korean medicine treatment for diabetes mellitus since 2013. The Journal of Internal Korean Medicine 2017;38(1):10-19.   DOI
15 Cho SI, Son MW, Hong KE. Glycemic control effects of Sanyak (Dioscoreae rhizoma) extract in prediabetic stage patients. The Journal of Korean Medicine 2010;31(5):146-66.
16 Liang F, Koya D. Acupuncture: is it effective for treatment of insulin resistance? Diabetes, obesity & metabolism 2010 Jul;12(7):555-69. doi:10.1111/j.1463-1326.2009.01192.x   DOI
17 Daejeon University Korean Medicine Hospital. Korean Medicine Hospital Formulary. Daejeon University Korean Medicine Hospital; p. 208.
18 Commitee of Clinical Practice Guideline. Treatment guideline for diabetes. Seoul: Korean diabetes association; 2015.
19 Donnapee S, Li J, Yang X, Ge AH, Donkor PO, Gao X, et al. Cuscuta chinensis Lam.: A systematic review on ethnopharmacology, phytochemistry and pharmacology of an important traditional herbal medicine. Journal of ethnopharmacology 2014;157:292-308.   DOI
20 2019 국민건강통계; 보건복지부, 질병관리본부(국가승인통계 제117002호, 국민건강영양조사). Updated April 1, 2021. Accessed August 20, 2021. https://www.index.go.kr/potal/main/EachDtlPageDetail.do?idx_cd=1438
21 Kim YH, Chae US. 소갈(消渴)의 병인병기(病因病機)와 침구치료(鍼灸治療)에 관(關)한 문헌적(文獻的) 고찰(考察). Journal of Haehwa Medicine 1995;4(1):269-85.
22 Chang CL, Lin Y, Bartolome AP, Chen Y, Chiu S, Yang W. Herbal therapies for type 2 diabetes mellitus: chemistry, biology, and potential application of selected plants and compounds. Evidence-Based Complementary and Alternative Medicine 2013;2013:378657.   DOI