Nuclear Engineering and Technology

Korean Nuclear Society (한국원자력학회)
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Performance evaluation of an adjustable gantry PET (AGPET) for small animal PET imaging

  • Song, Hankyeol (Department of Radiation Convergence Engineering, Yonsei University) ;
  • Kang, In Soo (Department of Radiation Convergence Engineering, Yonsei University) ;
  • Kim, Kyu Bom (Department of Integrative Medicine, Major in Digital Healthcare, Yonsei University) ;
  • Park, Chanwoo (Department of Radiation Convergence Engineering, Yonsei University) ;
  • Baek, Min Kyu (Department of Radiation Convergence Engineering, Yonsei University) ;
  • Lee, Seongyeon (Department of Radiation Convergence Engineering, Yonsei University) ;
  • Chung, Yong Hyun (Department of Radiation Convergence Engineering, Yonsei University)
  • Received : 2020.11.15
  • Accepted : 2021.01.30
  • Published : 2021.08.25
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Abstract

A rectangular-shaped PET system with an adjustable gantry (AGPET) has been developed for imaging small animals. The AGPET system employs a new depth of interaction (DOI) method using a depth dependent reflector patterns and a new digital time pickoff method based on the pulse reconstruction method. To evaluate the performance of the AGPET, timing resolution, intrinsic spatial resolution and point source images were acquired. The timing resolution and intrinsic spatial resolution were measured using two detector modules and Na-22 gamma source. The PET images were acquired in two field of view (FOV) sizes, 30 mm and 90 mm, to demonstrate the characteristic of the AGPET. As a result of in the experiment results, the timing resolution was 0.9 ns using the pulse reconstruction method based on the bi-exponential model. The intrinsic spatial resolution was an average of 1.7 mm and the spatial resolution of PET images after DOI correction was 2.08 mm and 2.25 mm at the centers of 30 mm and 90 mm FOV, respectively. The results show that the proposed AGPET system provided higher sensitivity and resolution for small animal imaging.

Keywords

Acknowledgement

This work was supported by the Nuclear Safety Research Program through the Korea Foundation Of Nuclear Safety (KoFONS) using the financial resource granted by the Nuclear Safety and Security Commission (NSSC) of the Republic of Korea No. 1903013.

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