대한한방부인과학회지 (The Journal of Korean Obstetrics and Gynecology)

  • 제34권3호
  • /
  • Pages.175-191
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  • 2021
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  • 1229-4292(pISSN)
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  • 2508-3619(eISSN)
대한한방부인과학회 (The Society of Korean Medicine Obstetrics and Gynecology)
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한방 치료로 고안드로겐혈증을 개선한 다낭성 난소 증후군 연속증례연구

A Case Series of Polycystic Ovary Syndrome with Improved Hyperandrogenism Treated with Korean Medicine

  • 신혜규 (세명대학교 충주한방병원) ;
  • 배지용 (세명대학교 충주한방병원) ;
  • 지영근 (인애한의원 일산점) ;
  • 안해인 (한국한의약진흥원 한의표준임상진료지침 개발사업단) ;
  • 윤영흠 (한국한의약진흥원 한의표준임상진료지침 개발사업단) ;
  • 김남권 (한국한의약진흥원 한의표준임상진료지침 개발사업단)
  • Shin, Haegue (Chungju Hospital of Korean Medicine, Se-Myung University) ;
  • Bae, Ji-Yong (Chungju Hospital of Korean Medicine, Se-Myung University) ;
  • Ji, Young-Geun (Ilsan Inae Korean Medicine Clinic) ;
  • Ahn, Hae In (Guideline Center for Korean Medicine, National Institute for Korean Medicine Development) ;
  • Yoon, Youngheum (Guideline Center for Korean Medicine, National Institute for Korean Medicine Development) ;
  • Kim, Namkwen (Guideline Center for Korean Medicine, National Institute for Korean Medicine Development)
  • 투고 : 2021.07.16
  • 심사 : 2021.08.27
  • 발행 : 2021.08.27
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초록

Objectives: This study aims to analyze the medical record of eight cases of polycystic ovary syndrome (PCOS) in a local Korean medicine clinic, in order to provide evidence on Korean medicine treatment of PCOS and to suggest the direction of future studies. Methods: The medical records of eight cases diagnosed with PCOS based on 2003 Rotterdam Criteria and whose total testosterone level was 0.53 ng/ml and over were retrospectively analyzed. The primary outcome was total testosterone level, and the secondary outcomes included luteinizing hormone (LH) and follicle stimulating hormone (FSH) levels, LH/FSH ratio, weight, last mentrual period (LMP), numerical rating scale (NRS) score of dysmenorrhea, and other associated symptoms pre- and post-treatment. Korean medicine treatment consists of the complex herbal prescription consisting of Yukmijihwang-tang, Baekho-tang, Daesiho-tang, and Gyejibokryeong-hwan, modified according to symptoms; acupuncture and electroacupuncture on 中脘 (CV12), 下脘 (CV10), 關元 (CV4), 石門 (CV5), 合谷 (LI4), 太衝 (LR3), 三陰交 (SP6), and 懸鍾 (GB39); and indirect moxibustion on 神闕 (CV8). Results: The average total testosterone level lowered statistically significantly after the treatment. The average FSH and LH levels lowered with insignificance, while the average LH/FSH ratio and weight lowered statistically significantly. During the treatment period of three to six months, every patient had the menstrual cycle shortened except for one case; and two cases with infertility problem succeeded in being pregnant. There was no adverse event. Conclusions: The Korean medicine treatment was found effective in treating PCOS, especially regarding hyperandrogenism, amenorrhea or oligomenorrhea, and infertility.

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과제정보

본 논문은 한국한의약진흥원 한의표준임상진료지침 개발사업단(HI16C0275) '2020년 임상증례 발굴 연구 지원사업'의 지원을 받아 수행된 연구임.

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