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http://dx.doi.org/10.15204/jkobgy.2021.34.3.175

A Case Series of Polycystic Ovary Syndrome with Improved Hyperandrogenism Treated with Korean Medicine  

Shin, Haegue (Chungju Hospital of Korean Medicine, Se-Myung University)
Bae, Ji-Yong (Chungju Hospital of Korean Medicine, Se-Myung University)
Ji, Young-Geun (Ilsan Inae Korean Medicine Clinic)
Ahn, Hae In (Guideline Center for Korean Medicine, National Institute for Korean Medicine Development)
Yoon, Youngheum (Guideline Center for Korean Medicine, National Institute for Korean Medicine Development)
Kim, Namkwen (Guideline Center for Korean Medicine, National Institute for Korean Medicine Development)
Publication Information
The Journal of Korean Obstetrics and Gynecology / v.34, no.3, 2021 , pp. 175-191 More about this Journal
Abstract
Objectives: This study aims to analyze the medical record of eight cases of polycystic ovary syndrome (PCOS) in a local Korean medicine clinic, in order to provide evidence on Korean medicine treatment of PCOS and to suggest the direction of future studies. Methods: The medical records of eight cases diagnosed with PCOS based on 2003 Rotterdam Criteria and whose total testosterone level was 0.53 ng/ml and over were retrospectively analyzed. The primary outcome was total testosterone level, and the secondary outcomes included luteinizing hormone (LH) and follicle stimulating hormone (FSH) levels, LH/FSH ratio, weight, last mentrual period (LMP), numerical rating scale (NRS) score of dysmenorrhea, and other associated symptoms pre- and post-treatment. Korean medicine treatment consists of the complex herbal prescription consisting of Yukmijihwang-tang, Baekho-tang, Daesiho-tang, and Gyejibokryeong-hwan, modified according to symptoms; acupuncture and electroacupuncture on 中脘 (CV12), 下脘 (CV10), 關元 (CV4), 石門 (CV5), 合谷 (LI4), 太衝 (LR3), 三陰交 (SP6), and 懸鍾 (GB39); and indirect moxibustion on 神闕 (CV8). Results: The average total testosterone level lowered statistically significantly after the treatment. The average FSH and LH levels lowered with insignificance, while the average LH/FSH ratio and weight lowered statistically significantly. During the treatment period of three to six months, every patient had the menstrual cycle shortened except for one case; and two cases with infertility problem succeeded in being pregnant. There was no adverse event. Conclusions: The Korean medicine treatment was found effective in treating PCOS, especially regarding hyperandrogenism, amenorrhea or oligomenorrhea, and infertility.
Keywords
Korean Medicine; Polycystic Ovary Syndrome; Hyperandrogenism; Yukmijihwang-tang; Baekho-tang; Gyejibokryeong-hwan;
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Times Cited By KSCI : 2  (Citation Analysis)
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