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Cellular Risk Assessment of Cells Exposed to Extremely Low Frequency Electromagnetic Fields

극저주파 자기장 노출에 의한 세포 유해성 평가

  • Kang, Heungsik (Department of Mechatronics Engineering, Chungnam National University) ;
  • Lee, Seongpyo (Department of Biochemistry, Chungnam National University) ;
  • Noh, Myunggyu (Department of Mechatronics Engineering, Chungnam National University) ;
  • Kim, Ki-Jung (Department of Smart Car Engineering, Doowon Technical University) ;
  • Kim, Keekwang (Department of Biochemistry, Chungnam National University)
  • 강흥식 (충남대학교 메카트로닉스공학과) ;
  • 이성표 (충남대학교 생화학과) ;
  • 노명규 (충남대학교 메카트로닉스공학과) ;
  • 김기정 (두원공과대학교) ;
  • 김기광 (충남대학교 생화학과)
  • Received : 2021.02.22
  • Accepted : 2021.05.20
  • Published : 2021.05.28

Abstract

Humans are environmentally exposed to various electromagnetic fields, but the evaluation of the harmfulness of electromagnetic field and the development of a system therefor are still incomplete. We aimed to develop a system for evaluating biohazard against electromagnetic fields, and to determine biohazard through the system. An extremely-low frequency magnetic field generator was designed and manufactured, and the output reliability of the device was verified. Using this device, the effect on the formation of cellular stress-granules and the cell cycle progression of cells exposed to high magnetic fields of 6 mT and 60 Hz was confirmed. As a result, exposure to high magnetic fields of 6 hr, 12 hr and 36 hr did not affect the formation of cell stress-induced granules and the cell division cycle. These results are an important basis for the determination of biohazard to the extremely-low frequency high magnetic field.

인간은 환경적으로 다양한 전자기파에 노출되어 있으나 전자기파에 대한 유해성 평가 및 이를 위한 시스템의 개발은 미진한 상태이다. 따라서 우리는 전자기파에 대한 생물학적 유해성 평가를 위한 시스템을 개발하고, 시스템을 통한 생물학적 유해성 평가를 하고자 한다. 본 연구에서는 극저주파 자기장 발생장치를 설계 및 제작하였으며 장치의 출력 신뢰성을 확인하였다. 이 장치를 활용하여 고자기장인 6 mT와 60 Hz에 노출된 세포의 세포스트레스 유도과립(Cellular stress-granules)의 형성 및 세포 분열 주기에 대한 영향을 확인하였다. 그 결과 6, 12 그리고 36시간 동안의 고자기장의 노출은 세포스트레스 유도과립의 형성 및 세포 분열 주기에 영향을 주지 않았다. 이러한 결과들은 극저주파 고자기장에 대한 생물학적 유해성 판단을 위한 중요한 기초 자료로 사용될 수 있을 것으로 판단된다.

Keywords

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