References
- Zhou P, Yang XL, Wang XG, Hu B, Zhang L, Zhang W, et al. 2020. A pneumonia outbreak associated with a new coronavirus of probable bat origin. Nature 579: 270-273. https://doi.org/10.1038/s41586-020-2012-7
- Zumla A, Chan JF, Azhar EI, Hui DS, Yuen KY. 2016. Coronaviruses - drug discovery and therapeutic options. Nat. Rev. Drug Discov. 15: 327-347. https://doi.org/10.1038/nrd.2015.37
- Cheng VC, Lau SK, Woo PC, Yuen KY. 2007. Severe acute respiratory syndrome coronavirus as an agent of emerging and reemerging infection. Clin. Microbiol. Rev. 20: 660-694. https://doi.org/10.1128/CMR.00023-07
- Chan JF, Lau SK, To KK, Cheng VC, Woo PC, Yuen KY. 2015. Middle East respiratory syndrome coronavirus: another zoonotic betacoronavirus causing SARS-like disease. Clin. Microbiol. Rev. 28: 465-522. https://doi.org/10.1128/CMR.00102-14
-
Lee JY, Bae S, Myoung J. 2019. Middle East respiratory syndrome Coronavirus-encoded accessory proteins impair MDA5-and TBK1-mediated activation of NF-
${\kappa}B$ . J. Microbiol. Biotechnol. 29: 1316-1323. https://doi.org/10.4014/jmb.1908.08004 - Gralinski LE, Baric RS. 2015. Molecular pathology of emerging coronavirus infections. J. Pathol. 235: 185-195. https://doi.org/10.1002/path.4454
- Velavan TP, Meyer CG. 2020. The COVID-19 epidemic. Trop. Med. Int. Health 25: 278-280. https://doi.org/10.1111/tmi.13383
- Lake MA. 2020. What we know so far: COVID-19 current clinical knowledge and research. Clin. Med (Lond). 20: 124-127. https://doi.org/10.7861/clinmed.2019-coron
- Guan WJ, Ni ZY, Hu Y, Liang WH, Ou CQ, He JX, et al. 2020. Clinical characteristics of Coronavirus disease 2019 in China. N. Engl. J. Med. 382: 1708-1720. https://doi.org/10.1056/NEJMoa2002032
- Li Q, Guan X, Wu P, Wang X, Zhou L, Tong Y, et al. 2020. Early transmission dynamics in Wuhan, China, of novel Coronavirus- Infected pneumonia. N. Engl. J. Med. 382: 1199-1207. https://doi.org/10.1056/NEJMoa2001316
- Prompetchara E, Ketloy C, Palaga T. 2020. Immune responses in COVID-19 and potential vaccines: Lessons learned from SARS and MERS epidemic. Asian Pac. J. Allergy Immunol. 38: 1-9.
- Cucinotta D, Vanelli M. 2020. WHO declares COVID-19 a pandemic. Acta Biomed. 91: 157-160.
- Lu S. 2020. Timely development of vaccines against SARS-CoV-2. Emerg. Microbes Infect. 9: 542-544. https://doi.org/10.1080/22221751.2020.1737580
- Lee J, Bae S, Myoung J. 2019. Generation of full-length infectious cDNA clones of middle east respiratory syndrome coronavirus. J. Microbiol. Biotechnol. 29: 999-1007. https://doi.org/10.4014/jmb.0905.05061
- Jiang S, He Y, Liu S. 2005. SARS vaccine development. Emerg. Infect. Dis. 11: 1016-1020. https://doi.org/10.3201/1107.050219
- Yong CY, Ong HK, Yeap SK, Ho KL, Tan WS. 2019. Recent advances in the vaccine development against Middle East respiratory syndrome-coronavirus. Front. Microbiol. 10: 1781. https://doi.org/10.3389/fmicb.2019.01781
- Lin JT, Zhang JS, Su N, Xu JG, Wang N, Chen JT, et al. 2007. Safety and immunogenicity from a phase I trial of inactivated severe acute respiratory syndrome coronavirus vaccine. Antivir. Ther. 12: 1107-1113.
- Martin JE, Louder MK, Holman LA, Gordon IJ, Enama ME, Larkin BD, et al. 2008. A SARS DNA vaccine induces neutralizing antibody and cellular immune responses in healthy adults in a Phase I clinical trial. Vaccine 26: 6338-6343. https://doi.org/10.1016/j.vaccine.2008.09.026
- Modjarrad K, Roberts CC, Mills KT, Castellano AR, Paolino K, Muthumani K, et al. 2019. Safety and immunogenicity of an anti- Middle East respiratory syndrome coronavirus DNA vaccine: a phase 1, open-label, single-arm, dose-escalation trial. Lancet Infect. Dis. 19: 1013-1022. https://doi.org/10.1016/S1473-3099(19)30266-X
- Ahmed SF, Quadeer AA, McKay MR. 2020. Preliminary identification of potential vaccine targets for the COVID-19 Coronavirus (SARS-CoV-2) based on SARS-CoV immunological studies. Viruses 12: 254. https://doi.org/10.3390/v12030254
- Dhama K, Sharun K, Tiwari R, Dadar M, Malik YS, Singh KP, et al. 2020. COVID-19, an emerging coronavirus infection: advances and prospects in designing and developing vaccines, immunotherapeutics, and therapeutics. Hum. Vaccin. Immunother. 16: 1232- 1238. https://doi.org/10.1080/21645515.2020.1735227
- Lu R, Zhao X, Li J, Niu P, Yang B, Wu H, et al. 2020. Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding. Lancet 395: 565-574. https://doi.org/10.1016/S0140-6736(20)30251-8
- Wrapp D, Wang N, Corbett KS, Goldsmith JA, Hsieh CL, Abiona O, et al. 2020. Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation. Science 367: 1260-1263. https://doi.org/10.1126/science.abb2507
- Yan R, Zhang Y, Li Y, Xia L, Guo Y, Zhou Q. 2020. Structural basis for the recognition of SARS-CoV-2 by full-length human ACE2. Science 367: 1444-1448. https://doi.org/10.1126/science.abb2762
- Zhou Y, Jiang S, Du L. 2018. Prospects for a MERS-CoV spike vaccine. Expert Rev. Vaccines 17: 677-686. https://doi.org/10.1080/14760584.2018.1506702
- Koyama S, Ishii KJ, Coban C, Akira S. 2008. Innate immune response to viral infection. Cytokine 43: 336-341. https://doi.org/10.1016/j.cyto.2008.07.009
- Thompson MR, Kaminski JJ, Kurt-Jones EA, Fitzgerald KA. 2011. Pattern recognition receptors and the innate immune response to viral infection. Viruses 3: 920-940. https://doi.org/10.3390/v3060920
- Teijaro JR. 2016. Type I interferons in viral control and immune regulation. Curr. Opin. Virol. 16: 31-40. https://doi.org/10.1016/j.coviro.2016.01.001
- Jensen S, Thomsen AR. 2012. Sensing of RNA viruses: a review of innate immune receptors involved in recognizing RNA virus invasion. J. Virol. 86: 2900-2910. https://doi.org/10.1128/JVI.05738-11
-
He L, Ding Y, Zhang Q, Che X, He Y, Shen H, et al. 2006. Expression of elevated levels of pro-inflammatory cytokines in SARS-CoVinfected
$ACE2^+$ cells in SARS patients: relation to the acute lung injury and pathogenesis of SARS. J. Pathol. 210: 288-297. https://doi.org/10.1002/path.2067 - Perlman S, Dandekar AA. 2005. Immunopathogenesis of coronavirus infections: implications for SARS. Nat. Rev. Immunol. 5: 917- https://doi.org/10.1038/nri1732
- Zumla A, Hui DS, Perlman S. 2015. Middle East respiratory syndrome. Lancet 386: 995-1007. https://doi.org/10.1016/S0140-6736(15)60454-8
- Snijder EJ, van der Meer Y, Zevenhoven-Dobbe J, Onderwater JJ, van der Meulen J, Koerten HK, et al. 2006. Ultrastructure and origin of membrane vesicles associated with the severe acute respiratory syndrome coronavirus replication complex. J. Virol. 80: 5927- 5940. https://doi.org/10.1128/JVI.02501-05
- Blanchard E, Roingeard P. 2015. Virus-induced double-membrane vesicles. Cell. Microbiol. 17: 45-50. https://doi.org/10.1111/cmi.12372
- Haller O, Kochs G. 2002. Interferon-induced mx proteins: dynamin-like GTPases with antiviral activity. Traffic 3: 710-717. https://doi.org/10.1034/j.1600-0854.2002.31003.x
- Sen GC. 2001. Viruses and interferons. Annu. Rev. Microbiol. 55: 255-281. https://doi.org/10.1146/annurev.micro.55.1.255
- Kurche JS, Haluszczak C, McWilliams JA, Sanchez PJ, Kedl RM. 2012. Type I IFN-dependent T cell activation is mediated by IFNdependent dendritic cell OX40 ligand expression and is independent of T cell IFNR expression. J. Immunol. 188: 585-593. https://doi.org/10.4049/jimmunol.1102550
- Lee JY, Kim SJ, Myoung J. 2019. Middle East respiratory syndrome Coronavirus-Encoded ORF8b inhibits RIG-I-Like receptors in a differential mechanism. J. Microbiol. Biotechnol. 29: 2014-2021. https://doi.org/10.4014/jmb.1911.11024
- Lee JY, Bae S, Myoung J. 2019. Middle East respiratory syndrome coronavirus-encoded ORF8b strongly antagonizes IFN-beta promoter activation: its implication for vaccine design. J. Microbiol. 57: 803-811. https://doi.org/10.1007/s12275-019-9272-7
- Lokugamage KG, Schindewolf C, Menachery VD. 2020. SARS-CoV-2 sensitive to type I interferon pretreatment. bioRxiv 2020.2003.2007.982264.
- Team CC-R. 2020. Severe outcomes among patients with Coronavirus Disease 2019 (COVID-19) - United States, February 12- March 16, 2020. MMWR Morb Mortal Wkly Rep. 69: 343-346. https://doi.org/10.15585/mmwr.mm6912e2
- Shaw AC, Goldstein DR, Montgomery RR. 2013. Age-dependent dysregulation of innate immunity. Nat. Rev. Immunol. 13: 875-887. https://doi.org/10.1038/nri3547
- Li T, Qiu Z, Zhang L, Han Y, He W, Liu Z, et al. 2004. Significant changes of peripheral T lymphocyte subsets in patients with severe acute respiratory syndrome. J. Infect. Dis. 189: 648-651. https://doi.org/10.1086/381535
- Xie J, Fan HW, Li TS, Qiu ZF, Han Y. 2006. [Dynamic changes of T lymphocyte subsets in the long-term follow-up of severe acute respiratory syndrome patients]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 28: 253-255.
- Chen J, Qi T, Liu L, Ling Y, Qian Z, Li T, et al. 2020. Clinical progression of patients with COVID-19 in Shanghai, China. J. Infect. 80: e1-e6.
- Qin C, Zhou L, Hu Z, Zhang S, Yang S, Tao Y, et al. 2020. Dysregulation of immune response in patients with COVID-19 in Wuhan, China. Clin. Infect. Dis. 71: 762-768. https://doi.org/10.1093/cid/ciaa248
- Zheng HY, Zhang M, Yang CX, Zhang N, Wang XC, Yang XP, et al. 2020. Elevated exhaustion levels and reduced functional diversity of T cells in peripheral blood may predict severe progression in COVID-19 patients. Cell. Mol. Immunol. 17: 541-543. https://doi.org/10.1038/s41423-020-0401-3
- Channappanavar R, Fehr AR, Vijay R, Mack M, Zhao J, Meyerholz DK, et al. 2016. Dysregulated type I interferon and inflammatory monocyte-macrophage responses cause lethal pneumonia in SARS-CoV-infected mice. Cell Host Microbe. 19: 181-193. https://doi.org/10.1016/j.chom.2016.01.007
- Snell LM, Osokine I, Yamada DH, De la Fuente JR, Elsaesser HJ, Brooks DG. 2016. Overcoming CD4 Th1 cell fate restrictions to sustain antiviral CD8 T cells and control persistent virus infection. Cell. Rep. 16: 3286-3296. https://doi.org/10.1016/j.celrep.2016.08.065
- Wong CK, Lam CW, Wu AK, Ip WK, Lee NL, Chan IH, et al. 2004. Plasma inflammatory cytokines and chemokines in severe acute respiratory syndrome. Clin. Exp. Immunol. 136: 95-103. https://doi.org/10.1111/j.1365-2249.2004.02415.x
- Mahallawi WH, Khabour OF, Zhang Q, Makhdoum HM, Suliman BA. 2018. MERS-CoV infection in humans is associated with a pro-inflammatory Th1 and Th17 cytokine profile. Cytokine 104: 8-13. https://doi.org/10.1016/j.cyto.2018.01.025
- Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y, et al. 2020. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet 395: 497-506. https://doi.org/10.1016/S0140-6736(20)30183-5
- McElroy AK, Akondy RS, Davis CW, Ellebedy AH, Mehta AK, Kraft CS, et al. 2015. Human Ebola virus infection results in substantial immune activation. Proc. Natl. Acad. Sci. USA 112: 4719-4724. https://doi.org/10.1073/pnas.1502619112
- Thevarajan I, Nguyen THO, Koutsakos M, Druce J, Caly L, van de Sandt CE, et al. 2020. Breadth of concomitant immune responses prior to patient recovery: a case report of non-severe COVID-19. Nat. Med. 26: 453-455. https://doi.org/10.1038/s41591-020-0819-2
- Tisoncik JR, Korth MJ, Simmons CP, Farrar J, Martin TR, Katze MG. 2012. Into the eye of the cytokine storm. Microbiol. Mol. Biol. Rev. 76: 16-32. https://doi.org/10.1128/MMBR.05015-11
- Newton AH, Cardani A, Braciale TJ. 2016. The host immune response in respiratory virus infection: balancing virus clearance and immunopathology. Semin. Immunopathol. 38: 471-482. https://doi.org/10.1007/s00281-016-0558-0
- Ababneh M, Alrwashdeh M, Khalifeh M. 2019. Recombinant adenoviral vaccine encoding the spike 1 subunit of the Middle East Respiratory Syndrome Coronavirus elicits strong humoral and cellular immune responses in mice. Vet. World 12: 1554-1562. https://doi.org/10.14202/vetworld.2019.1554-1562
- Li G, Fan Y, Lai Y, Han T, Li Z, Zhou P, et al. 2020. Coronavirus infections and immune responses. J. Med. Virol. 92: 424-432. https://doi.org/10.1002/jmv.25685
- Li G, Chen X, Xu A. 2003. Profile of specific antibodies to the SARS-associated coronavirus. N. Engl. J. Med. 349: 508-509. https://doi.org/10.1056/NEJM200307313490520
- Cheng M, Chan CW, Cheung RC, Bikkavilli RK, Zhao Q, Au SW, et al. 2005. Cross-reactivity of antibody against SARS-coronavirus nucleocapsid protein with IL-11. Biochem. Biophys. Res. Commun. 338: 1654-1660. https://doi.org/10.1016/j.bbrc.2005.10.088
- Zhou G, Zhao Q. 2020. Perspectives on therapeutic neutralizing antibodies against the novel Coronavirus SARS-CoV-2. Int. J. Biol. Sci. 16: 1718-1723. https://doi.org/10.7150/ijbs.45123
- Mubarak A, Alturaiki W, Hemida MG. 2019. Middle East Respiratory Syndrome Coronavirus (MERS-CoV): infection, immunological response, and vaccine development. J. Immunol. Res. 2019: 6491738. https://doi.org/10.1155/2019/6491738
- Coleman CM, Liu YV, Mu H, Taylor JK, Massare M, Flyer DC, et al. 2014. Purified coronavirus spike protein nanoparticles induce coronavirus neutralizing antibodies in mice. Vaccine 32: 3169-3174. https://doi.org/10.1016/j.vaccine.2014.04.016
- Payne DC, Iblan I, Rha B, Alqasrawi S, Haddadin A, Al Nsour M, et al. 2016. Persistence of antibodies against Middle East Respiratory Syndrome Coronavirus. Emerg. Infect. Dis. 22: 1824-1826. https://doi.org/10.3201/eid2210.160706
- Liu W, Fontanet A, Zhang PH, Zhan L, Xin ZT, Baril L, et al. 2006. Two-year prospective study of the humoral immune response of patients with severe acute respiratory syndrome. J. Infect. Dis. 193: 792-795. https://doi.org/10.1086/500469
- Tang F, Quan Y, Xin ZT, Wrammert J, Ma MJ, Lv H, et al. 2011. Lack of peripheral memory B cell responses in recovered patients with severe acute respiratory syndrome: a six-year follow-up study. J. Immunol. 186: 7264-7268. https://doi.org/10.4049/jimmunol.0903490
- Zhang B, Zhou X, Zhu C, Feng F, Qiu Y, Feng J, et al. 2020. Immune phenotyping based on neutrophil-to-lymphocyte ratio and IgG predicts disease severity and outcome for patients with COVID-19. Front. Mol. Biosci. 7: 157. https://doi.org/10.3389/fmolb.2020.00157
- Haveri A, Smura T, Kuivanen S, Osterlund P, Hepojoki J, Ikonen N, et al. 2020. Serological and molecular findings during SARSCoV- 2 infection: the first case study in Finland, January to February 2020. Euro Surveill. 25: 2000266.
- Liu L, Wei Q, Lin Q, Fang J, Wang H, Kwok H, et al. 2019. Anti-spike IgG causes severe acute lung injury by skewing macrophage responses during acute SARS-CoV infection. JCI Insight. 4: e123158. https://doi.org/10.1172/jci.insight.123158
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