Progress in Medical Physics (한국의학물리학회지:의학물리)

Korean Society of Medical Physics (한국의학물리학회)
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Carbon Ion Therapy: A Review of an Advanced Technology

  • Kim, Jung-in (Department of Radiation Oncology, Seoul National University Hospital) ;
  • Park, Jong Min (Department of Radiation Oncology, Seoul National University Hospital) ;
  • Wu, Hong-Gyun (Department of Radiation Oncology, Seoul National University Hospital)
  • Received : 2020.05.29
  • Accepted : 2020.09.09
  • Published : 2020.09.30
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Abstract

This paper provides a brief review of the advanced technologies for carbon ion radiotherapy (CIRT), with a focus on current developments. Compared to photon beam therapy, treatment using heavy ions, especially a carbon beam, has potential advantages due to its physical and biological properties. Carbon ion beams with high linear energy transfer demonstrate high relative biological effectiveness in cell killing, particularly at the Bragg peak. With these unique properties, CIRT allows for accurate targeting and dose escalation for tumors with better sparing of adjacent normal tissues. Recently, the available CIRT technologies included fast pencil beam scanning, superconducting rotating gantry, respiratory motion management, and accurate beam modeling for the treatment planning system. These techniques provide precise treatment, operational efficiency, and patient comfort. Currently, there are 12 CIRT facilities worldwide; with technological improvements, they continue to grow in number. Ongoing technological developments include the use of multiple ion beams, effective beam delivery, accurate biological modeling, and downsizing the facility.

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