대한한의학방제학회지 (Herbal Formula Science)

  • 제28권2호
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  • Pages.157-167
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  • 2020
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  • 1229-1218(pISSN)
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  • 2288-5641(eISSN)
대한한의학방제학회 (The Korean Medicine Society for the Herbal Formula Study)
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황련해독탕의 위염 치료 효과에 대한 단일비교 임상연구

A Comparative Clinical Study on the Effect of Hwangryunhaedok-tang in Gastritis Treatment

  • 박범찬 (부산대학교한방병원 한방소아과) ;
  • 김희연 (부산대학교한방병원 한방소아과) ;
  • 김광연 (한국한의학연구원 한의기술응용센터) ;
  • 양주혜 (한국한의학연구원 한의기술응용센터) ;
  • 김경호 (한국한의학연구원 한의기술응용센터) ;
  • 도현주 (한국한의학연구원 한의기술응용센터) ;
  • 지선영 (한국한의학연구원 한의기술응용센터) ;
  • 최준용 (부산대학교한방병원 한방내과) ;
  • 김영우 (동국대학교 한의학과) ;
  • 박광일 (한국한의학연구원 한의기술응용센터) ;
  • 김기봉 (부산대학교한방병원 한방소아과)
  • Park, Beom-Chan (Department of Korean Pediatrics, Pusan National University Korean Medicine Hospital) ;
  • Kim, Hee-Yeon (Department of Korean Pediatrics, Pusan National University Korean Medicine Hospital) ;
  • Kim, Kwang-Youn (Korean Medicine Application Center, Korea Institute of Oriental Medicine) ;
  • Yang, Ju-Hye (Korean Medicine Application Center, Korea Institute of Oriental Medicine) ;
  • Kim, Kyungho (Korean Medicine Application Center, Korea Institute of Oriental Medicine) ;
  • Do, Hyun Ju (Korean Medicine Application Center, Korea Institute of Oriental Medicine) ;
  • Jee, Seon young (Korean Medicine Application Center, Korea Institute of Oriental Medicine) ;
  • Choi, Jun-Yong (Department of Korean Internal Medicine, Pusan National University Korean Medicine Hospital) ;
  • Kim, Young Woo (College of Korean Medicine, Dongguk University) ;
  • Park, Kwang Il (Korean Medicine Application Center, Korea Institute of Oriental Medicine) ;
  • Kim, Kibong (Department of Korean Pediatrics, Pusan National University Korean Medicine Hospital)
  • 투고 : 2020.04.10
  • 심사 : 2020.05.26
  • 발행 : 2020.05.31
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초록

Objectives : The purpose of this clinical study was to investigate the efficacy and safety of Hwangryunhaedok-tang on the gastritis treatment. Methods : A total of 20 subjects who visited Pusan National University Hospital from April 2nd, 2019 to September 2nd, 2019 were included. In this study, we evaluated the individual symptoms through questionnaires, laboratory test, BIA (Bioelectrical Impedance Analysis), and adverse reaction according to medication. Statistical analysis was performed with paired t-test and Wilcoxon Signed Rank test. Statistical significance was achieved if the probability was less than 5% (p < 0.05). Results : After medications, the total score of individual symptoms, primary outcome, was significantly decreased. In particular, individual symptoms such as upper abdominal pain, bloating, heartburn and trim showed significant improvement. However, no statistically significant differences were found in nausea/vomiting and anorexia. In additions, the laboratory test showed a statistically significant decrease in total cholesterol, but no statistically significant differences in results of BIA. In the safety evaluation, adverse reactions were not reported. Conclusions : Considering this results, we have confirmed the possibility of Hwangryunhaedok-tang to the gastritis treatment.

키워드

참고문헌

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