The Journal of Internal Korean Medicine (대한한방내과학회지)

The Society of Internal Korean Medicine (대한한방내과학회)
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The Effect of Herbal Medicine on Blood Glucose in Type 2 Diabetes Patients: A Retrospective Study

한약 복용이 제 2형 당뇨 환자의 혈당 변화에 미치는 영향 : 후항적 차트 리뷰

  • Yu, Chang-hwan (Division of Allergy, Immune and Respiratory System, Dept. of Internal Medicine, College of Korean Medicine, Kyung Hee University) ;
  • Kang, Sung-woo (Division of Allergy, Immune and Respiratory System, Dept. of Internal Medicine, College of Korean Medicine, Kyung Hee University) ;
  • Hong, Sung-eun (Division of Allergy, Immune and Respiratory System, Dept. of Internal Medicine, College of Korean Medicine, Kyung Hee University) ;
  • Kim, Kwan-il (Division of Allergy, Immune and Respiratory System, Dept. of Internal Medicine, College of Korean Medicine, Kyung Hee University) ;
  • Jung, Hee-jae (Division of Allergy, Immune and Respiratory System, Dept. of Internal Medicine, College of Korean Medicine, Kyung Hee University) ;
  • Lee, Beom-joon (Division of Allergy, Immune and Respiratory System, Dept. of Internal Medicine, College of Korean Medicine, Kyung Hee University)
  • 유창환 (경희대학교 대학원 임상한의학과 폐계내과학교실) ;
  • 강성우 (경희대학교 대학원 임상한의학과 폐계내과학교실) ;
  • 홍성은 (경희대학교 대학원 임상한의학과 폐계내과학교실) ;
  • 김관일 (경희대학교 대학원 임상한의학과 폐계내과학교실) ;
  • 정희재 (경희대학교 대학원 임상한의학과 폐계내과학교실) ;
  • 이범준 (경희대학교 대학원 임상한의학과 폐계내과학교실)
  • Received : 2020.11.06
  • Accepted : 2020.12.21
  • Published : 2020.12.30
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Abstract

Objective: This study was conducted to evaluate the effect of herbal medicine on blood glucose in diabetic patients. Methods: The subjects were patients with diabetes mellitus (DM) who had been admitted to Kyung Hee University Korean Medicine Hospital for more than 8 weeks for a primary diagnosis other than DM and who had taken herbal medicine for more than 8 weeks from January 2010 to February 2020. The medical records were analyzed retrospectively to confirm the characteristics of the subjects, and examination results included hemoglobin A1c (HbA1c), total cholesterol, triglyceride, low-density lipoprotein cholesterol (LDL), high-density lipoprotein cholesterol (HDL), aspartate aminotransferase (AST), alanine aminotransferase (ALT), blood urea nitrogen (BUN), and creatinine. Changes in HbA1c before and after taking herbal medicine and changes according to subgroups were analyzed. Results: A total of 149 subjects with type 2 DM were selected as participants. After taking the herbal medicine, the HbA1c value was significantly decreased, and the statistical significance was maintained even when the effect of controlling antidiabetic agents was excluded. The decrease in HbA1c was higher in the poor glycemic control group. Liver and kidney functions did not show any significant changes after taking the herbal medicine. Conclusions: Administration of herbal medicine for a long period of 8 weeks or longer did not increase HbA1c in patients with DM complicated by other various diseases.

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