대한한방내과학회지 (The Journal of Internal Korean Medicine)

대한한방내과학회 (The Society of Internal Korean Medicine)
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한약복용이 간기능에 미치는 영향 : 국내 문헌에 대한 체계적 고찰

The Effect of Herbal Medicine on Liver Function: A Systematic Review of the Korean Literature

  • 하다정 (동의대학교 한의과대학 내과학교실) ;
  • 제유란 (동의대학교 한의과대학 내과학교실) ;
  • 김경림 (동의대학교 한의과대학 내과학교실) ;
  • 박상은 (동의대학교 한의과대학 내과학교실)
  • Ha, Da-jung (Dept. of Oriental Medicine, Dong-Eui University) ;
  • Je, Yu-ran (Dept. of Oriental Medicine, Dong-Eui University) ;
  • Kim, Kyong-lim (Dept. of Oriental Medicine, Dong-Eui University) ;
  • Park, Sang-eun (Dept. of Oriental Medicine, Dong-Eui University)
  • 투고 : 2020.09.09
  • 심사 : 2021.01.08
  • 발행 : 2020.12.30
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초록

Objective: The aim of this study was to provide a systematic review of the Korean literature on the influence of herbal medicine on liver function. Additionally, we tried to estimate the change in the data on liver function tests (LFTs) and the incidence of liver injury (LI) after taking herbal medicine. Methods: Systematic literature searches were performed on 6 major Korean databases (Research Information Sharing Service (RISS), Korea Institute of Science and Technology information (KISTI), National Assembly Electronic Library, Korean Medical database (KMBASE), Korean Traditional Portal, and Dongui University Electronic Library) from January 2010 to June 2020. No restrictions were placed on the types of publications, which included grey literature. Results: The data indicate that herbal medicine might be a minor cause of LI in Korea. However the results are not supported strongly enough to verify the safety issues because of the limitations of the original studies. Conclusions: Additional well-planned studies are still needed that can overcome the heterogeneity and the considerable methodological flaws in the analyzed studies.

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참고문헌

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  1. 항고지혈증제에 의한 약인성 간손상 발생 치험 1례 vol.42, pp.5, 2020, https://doi.org/10.22246/jikm.2021.42.5.777