The Korean Journal of Food And Nutrition (한국식품영양학회지)

The Korean Society of Food and Nutrition (한국식품영양학회)
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Effect of Monounsaturated Fatty Acid-enriched Peanut Consumption on Serum Lipid in High Fat Diet-induced Mice

고지방 식이 유도 비만 마우스에서 고올레산 땅콩 섭취의 혈장 지질 개선 효과

  • Oh, Eunyoung (Dept. of Southern Area Crop Science, National Institute of Crop Science, Rural Development Administration) ;
  • Pae, Suk-Bok (Dept. of Southern Area Crop Science, National Institute of Crop Science, Rural Development Administration) ;
  • Kim, Sungup (Dept. of Southern Area Crop Science, National Institute of Crop Science, Rural Development Administration) ;
  • Kim, Jung-In (Dept. of Southern Area Crop Science, National Institute of Crop Science, Rural Development Administration) ;
  • Lee, Myoung Hee (Dept. of Southern Area Crop Science, National Institute of Crop Science, Rural Development Administration) ;
  • Sung, Jung Sook (Dept. of Southern Area Crop Science, National Institute of Crop Science, Rural Development Administration) ;
  • Ha, Tae Joung (Planning and Coordination Bureau, Rural Development Administration)
  • 오은영 (농촌진흥청 국립식량과학원 남부작물부) ;
  • 배석복 (농촌진흥청 국립식량과학원 남부작물부) ;
  • 김성업 (농촌진흥청 국립식량과학원 남부작물부) ;
  • 김정인 (농촌진흥청 국립식량과학원 남부작물부) ;
  • 이명희 (농촌진흥청 국립식량과학원 남부작물부) ;
  • 성정숙 (농촌진흥청 국립식량과학원 남부작물부) ;
  • 하태정 (농촌진흥청 연구정책국)
  • Received : 2020.11.06
  • Accepted : 2020.12.08
  • Published : 2020.12.31
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Abstract

This study was conducted to evaluate the effect of high-oleate and normal-oleate peanut consumption on adipose mass and serum lipids in obese-induced C57BL/6J mice. After four weeks of the high-fat diet, mice were randomly divided into six groups: normal control (NC) diet, high-fat control (HFC) diet, high-oleate peanut-seed (HOPS) diet, normal-oleate peanut-seed (NOPS) diet, high-oleate peanut-oil (HOPO) diet, and olive-oil (OO) diet. After four weeks, all four experimental diet groups showed significantly lower body weight and epididymal fat weight than HFC group. In four experimental diet groups, serum triglycerides (TG), total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-C) were significantly lower, and high-density lipoprotein cholesterol (HDL-C) was significantly higher than HFC group. TG was significantly decreased in HOPS group (92.1±1.2 mg/dL) than NOPS group (101.7±5.3 mg/dL, p<0.05). Similarly, LDL-C was significantly lower in HOPS group (66.1±2.8 mg/dL) than NOPS (76.9±1.5 mg/dL, p<0.05), on the other hand, HDL-C indicated a significant elevation in HOPS (50.5±2.1 mg/dL) than NOPS group (45.2±1.6 mg/dL, p<0.05). This result suggests that the consumption of high-oleate peanut has a favorable effect on the plasma lipid profile.

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References

  1. Asif M. 2011. Health effects of omega-3, 6, 9 fatty acids: Perilla frutescens is a good example of plant oils. Orient Pharm Exp Med 11:51-59 https://doi.org/10.1007/s13596-011-0002-x
  2. Baum SJ, Kris-Etherton PM, Willett WC, Lichtenstein AH, Rudel LL, Maki KC, Whelan J, Ramsden CE, Block RC. 2012. Fatty acids in cardiovascular health and disease: A comprehensive update. J Clin Lipidol 6:216-234 https://doi.org/10.1016/j.jacl.2012.04.077
  3. Carson JAS, Anderson CAM. 2020. Dietary cholesterol and cardiovascular risk: A science advisory from the American Heart Association. Circulation 141:39-53
  4. Castro-Barquero S, Lamuela-Raventos RM, Domenech M, Estruch R. 2018. Relationship between mediterranean dietary polyphenol intake and obesity. Nutrients 10:1523 https://doi.org/10.3390/nu10101523
  5. Chu Y, Holbrook CC, Ozias-Akins P. 2009. Two alleles of ahFAD2B control the high oleic acid trait in cultivated peanut. Crop Sci 49:2029-2036 https://doi.org/10.2135/cropsci2009.01.0021
  6. Goncalves-de-Albuquerque CF, Medeiros-de-Moraes IM, Oliveira FMJ, Burth P, Bozza PT, Faria MVC, Silva AR, Castro-Faria-Neto HC. 2016. Omega-9 oleic acid induces fatty acid oxidation and decreases organ dysfunction and mortality in experimental sepsis. PLOS ONE 11:e0153607 https://doi.org/10.1371/journal.pone.0153607
  7. Hodson L, Skeaff CM, Chisholm WAH. 2001. The effect of replacing dietary saturated fat with polyunsaturated or monounsaturated fat on plasma lipids in free-living young adults. Eur J Clin Nutr 55:908-915 https://doi.org/10.1038/sj/ejcn/1601234
  8. Hsu SC, Huang CJ. 2006. Reduced fat mass in rats fed a high oleic acid-rich safflower oil diet is associated with changes in expression of hepatic PPARα and adipose SREBP-1cregulated genes. J Nutr 136:1779-1785 https://doi.org/10.1093/jn/136.7.1779
  9. Huth PJ, Fulgoni VL, Larson BT. 2015. A systematic review of high-oleic vegetable oil substitutions for other fats and oils on cardiovascular disease risk factors: Implications for novel high-oleic soybean oils. Adv Nutr 6:674-693 https://doi.org/10.3945/an.115.008979
  10. Janila P, Pandey MK, Shasidhar Y, Variath MT, Sriswathi M, Khera P, Manohar SS, Nagesh P, Vishwakarma MK, Mishra GP, Radhakrishnan T, Manivannan N, Dobariya KL, Vasanthi RP, Varshney RK. 2016. Molecular breeding for introgression of fatty acid desaturase mutant alleles (ahFAD2A and ahFAD2B) enhances oil quality in high and low oil containing peanut genotypes. Plant Sci 242:203-213 https://doi.org/10.1016/j.plantsci.2015.08.013
  11. Jung S, Powell G, Moore K, Abbott A. 2000. The high oleate trait in the cultivated peanut [Arachis hypogaea L.]. II. Molecular basis and genetics of the trait. Mol Gen Genet 263:806-811 https://doi.org/10.1007/s004380000243
  12. Kim MY, Kim H, Lee Y, Kim MH, Lee JY, Lee B. 2019. Enzyme inhibitory and anti-proliferation effects of peanut skin extracts depending on cultivar. Korean J Food Nutr 32:511-521
  13. Korea Agro-Fisheries & Food Trade Corporation. 2017. Processed food consumption behavior survey report: Edible oil market. Available from http://www.atfis.or.kr [cited 10 October 2020]
  14. Korean Ministry of Agriculture, Food and Rural Affairs. 2019. 2019 Statistic report of agriculture and food. Available from https://lib.mafra.go.kr [cited 10 October 2020]
  15. Kris-Etherton PM, Zhao G, Binkoski AE, Stacie M, Coval BS, Etherton TD. 2001. The effects of nuts on coronary heart disease risk. Nutr Rev 59:103-111 https://doi.org/10.1111/j.1753-4887.2001.tb06996.x
  16. Lee C. 2001. The changes in the physico-chemical properties of peanut milk by processing conditions. Korean J Food Nutr 14:199-203
  17. Lee YR. 2019. Antioxidant activity of peanut flours with germination and roasting. Korean J Food Nutr 32:155-159 https://doi.org/10.9799/KSFAN.2019.32.2.155
  18. Lim HJ, Kim MS, Kim DS, Kim HS, Pae SB, Kim JK, Shin EC. 2017. Comparison of lipid constituents and oxidative properties between normal and high-oleic peanuts grown in Korea. Korean J Food Sci Technol 49:235-241 https://doi.org/10.9721/KJFST.2017.49.3.235
  19. Lou-Bonafonte JM, Arnal C, Navarro MA, Osada J. 2012. Efficacy of bioactive compounds from extra virgin olive oil to modulate atherosclerosis development. Mol Nutr Food Res 56:1043-1057 https://doi.org/10.1002/mnfr.201100668
  20. Martinez-Gonzalez MA, Sanchez-Villegas A. 2004. The emerging role of Mediterranean diets in cardiovascular epidemiology: Monounsaturated fats, olive oil, red wine or the whole pattern? Eur J Epidemiol 19:9-13 https://doi.org/10.1023/B:EJEP.0000013351.60227.7b
  21. Mata P, Alvarez-Sala LA, Rubio MJ, Nuno J, De Oya M. 1992. Effects of long-term monounsaturated- vs polyunsaturated-enriched diets on lipoproteins in healthy men and women. Am J Clin Nutr 55:846-850 https://doi.org/10.1093/ajcn/55.4.846
  22. Mente A, De Koning L, Shannon HS, Anand SS. 2009. A systematic review of the evidence supporting a causal link between dietary factors and coronary heart disease. Arch Intern Med 169:659-669 https://doi.org/10.1001/archinternmed.2009.38
  23. Norden AJ, Gorbet DW, Knauft DA, Young CT. 1987. Variability in oil quality among peanut genotypes in the Florida breeding program. Peanut Sci 14:7-11 https://doi.org/10.3146/i0095-3679-14-1-3
  24. Pae SB, Cheong YK, Shim KB, Hwang CD, Lee MH, Jung CS, Kang CW, Park KY, Park CB, Choi GH, Lee JC, Kim IJ, Kim JK. 2008. A new short stem, lodging resistance and high yielding peanut "Charmpyeong". Korean J Breed Sci 40:168-172
  25. Pae SB, Hwang CD, Lee MH, Kim SU, Oh KW, Lee BK, Park CH, Park KY, Baek IY, Jun YC. 2016. A high oleate peanut variety 'K-Ol'. Korean J Breed Sci 48:313-318 https://doi.org/10.9787/KJBS.2016.48.3.313
  26. Park JW, Kim MY, Kim MO, Lee HR, Lee JJ, Kim SK, Jeong HS, Lee YR. 2018. The quality characteristics of rice pie adding roasted peanut and peanut sprout flour. Korean J Food Nutr 31:766-773 https://doi.org/10.9799/KSFAN.2018.31.5.766
  27. Rural Development Administration. 2018. Oilseed Crop. pp. 184-196. Human culter Arirang
  28. Schwingshackl L, Hoffmann G. 2014. Monounsaturated fatty acids, olive oil and health status: A systematic review and meta-analysis of cohort studies. Lipids Health Dis 13:154 https://doi.org/10.1186/1476-511X-13-154
  29. Segura R, Javierre C, Lizarraga MA, Ros E. 2006. Other relevant components of nuts: Phytosterols, folate and minerals. Br J Nutr 96:S36-S44 https://doi.org/10.1017/BJN20061862
  30. Statistics Korea. 2020. Causes of death statistics. Available from http://kosis.kr [cited 10 October 2020]
  31. Tabeshpour J, Razavi BM, Hosseinzadeh H. 2017. Effects of avocado (Persea americana) on metabolic syndrome: a comprehensive systematic review. Phytother Res 31:819-837 https://doi.org/10.1002/ptr.5805
  32. Wang ML, Chen CY, Tonnis B, Barkley NA, Pinnow DL, Pittman RN, Davis J, Holbrook CC, Stalker HT, Pederson GA. 2013. Oil, fatty acid, flavonoid, and resveratrol content variability and FAD2A functional SNP genotypes in the U.S. peanut mini-core collection. J Agric Food Chem 61: 2875-2882 https://doi.org/10.1021/jf305208e
  33. Yang SC, Lin SH, Chang JS, Chien YW. 2017. High fat diet with a high monounsaturated fatty acid and polyunsaturated/saturated fatty acid ratio suppresses body fat accumulation and weight gain in obese hamsters. Nutrients 9:1148 https://doi.org/10.3390/nu9101148