Journal of Sensor Science and Technology (센서학회지)

The Korean Sensors Society (한국센서학회)
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Analysis of Breath from Diabetic Patients Based on a One-chip-type Sensor Array

  • Yu, Joon-Boo (Division of Electronics, Information & Communication Eng., Kangwon National Unversity, Kangwon National University) ;
  • Jang, Byoung Kuk (Division of Gastroenterology & Hepatology, Department of Internal Medicine, Keimyung University Dongsan Medical Center) ;
  • Byun, Hyung-Gi (Division of Electronics, Information & Communication Eng., Kangwon National Unversity, Kangwon National University)
  • Received : 2019.07.19
  • Accepted : 2019.07.30
  • Published : 2019.07.31
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Abstract

Based on the results of studies on acetone excretion in diabetic patients, a one - chip sensors array was fabricated by combining acetone-selective sensor materials and volatile-organic-compound sensitive sensor materials. An electonic-nose was implemented using a sensor array and confirmed selectivity for five gases. In this system, the excretion of diabetic patients and controls was sampled with solid phase microextraction fiber and transferred to the sensor array. Although the control and diabetic patients were distinct, several samples failed. In the control group, the results of blood tests were normal, but patients were highly obese. In addition, the gas chromatography mass spectrometry results for the subjects revealed chemicals that are external factors.

Keywords

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Fig. 1. Graph normalizing the sensitivity for each gas: acetone, ethanol, NO, toluene, and xylene

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Fig. 2. Normalization of sensitivity for control and diabetic patients measured by the sensor array

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Fig. 3. GC-MS analysis of breath of normal and diabetic patients

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Fig. 4. PCA results by expiration of diabetic patients and control group

Table 1. Blood analysis of normal and diabetic patients

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