DOI QR코드

DOI QR Code

Reference intervals for blood metabolic profiles of Holstein cows in Korea

국내 젖소의 혈액 대사인자 프로파일 분석

  • Jung, Suk-Han (National Institute of Animal Science, Rural Development Administration) ;
  • Jung, Young-Hun (National Institute of Animal Science, Rural Development Administration) ;
  • Choe, Changyong (National Institute of Animal Science, Rural Development Administration) ;
  • Do, Yoon Jung (National Institute of Animal Science, Rural Development Administration) ;
  • Cho, Ara (National Institute of Animal Science, Rural Development Administration) ;
  • Oh, Sang-Ik (National Institute of Animal Science, Rural Development Administration) ;
  • Kim, Eunju (National Institute of Animal Science, Rural Development Administration) ;
  • Ha, Seungmin (National Institute of Animal Science, Rural Development Administration) ;
  • Jeong, Ha Yeon (National Institute of Animal Science, Rural Development Administration) ;
  • Yoo, Jae Gyu (National Institute of Animal Science, Rural Development Administration) ;
  • Kim, Suhee (National Institute of Animal Science, Rural Development Administration)
  • 정숙한 (농촌진흥청 국립축산과학원) ;
  • 정영훈 (농촌진흥청 국립축산과학원) ;
  • 최창용 (농촌진흥청 국립축산과학원) ;
  • 도윤정 (농촌진흥청 국립축산과학원) ;
  • 조아라 (농촌진흥청 국립축산과학원) ;
  • 오상익 (농촌진흥청 국립축산과학원) ;
  • 김은주 (농촌진흥청 국립축산과학원) ;
  • 하승민 (농촌진흥청 국립축산과학원) ;
  • 정하연 (농촌진흥청 국립축산과학원) ;
  • 류재규 (농촌진흥청 국립축산과학원) ;
  • 김수희 (농촌진흥청 국립축산과학원)
  • Received : 2018.11.30
  • Accepted : 2019.04.10
  • Published : 2019.06.30

Abstract

Metabolic profile test is used to evaluate nutritional imbalance and metabolic disease in dairy cows. The reference intervals of metabolic parameters may change according to nation, region, decades, and maintenance system. Despite the need to be periodically updated for the reference intervals of metabolic parameters, it has rarely been investigated in Korea. Therefore, this aim of study was to provide the reference intervals of metabolic parameters using dairy cows surveyed in Korea during recent years. A metabolic profile test was conducted for 2,976 clinically healthy dairy cows in Korea. Blood samples were collected for the analysis of serum metabolites. This study provided reference intervals of thirteen metabolic parameters (${\beta}$-hydroxybutyrate [${\beta}-HB$], non-esterified fatty acids [NEFA], glucose, total cholesterol [T-COL], total protein, albumin, globulin, blood urea nitrogen [BUN], aspartate aminotransferase [AST], gamma-glutamyl transferase [GGT], calcium, phosphorus, and magnesium). BUN and AST values of the current study were higher than those of previous studies. In the present study, the other metabolic parameters showed low or similar value compared to previous results. Moreover, ${\beta}-HB$, NEFA, T-COL, ALB, BUN, AST, and GGT values were affected by lactation period. This study provided information on the reference intervals of metabolites in healthy dairy cows in Korea. The reference intervals from the present study would be useful in managing and diagnosing disease of dairy cows. However, careful attention should be given in interpreting disease condition for metabolites affected by lactation.

Keywords

Table 1. Information on dairy cow population surveyed in this study

GCOSBX_2019_v42n2_121_t0001.png 이미지

Table 3. Comparison of metabolic parameters among different stages of lactation in dairy cows

GCOSBX_2019_v42n2_121_t0002.png 이미지

Table 2. Reference intervals for metabolic parameters in dairy cows

GCOSBX_2019_v42n2_121_t0003.png 이미지

References

  1. Brscic M, Cozzi G, Lora I, Stefani AL, Contiero B, Ravarotto L, Gottardo F. 2015. Short communication: Reference limits for blood analytes in Holstein late-pregnant heifers and dry cows: Effects of parity, days relative to calving, and season. J Dairy Sci 98: 7886-7892. https://doi.org/10.3168/jds.2015-9345
  2. Cameron RE, Dyk PB, Herdt TH, Kaneene JB, Miller R, Bucholtz HF, Liesman JS, Vandehaar MJ, Emery RS. 1998. Dry cow diet, management, and energy balance as risk factors for displaced abomasum in high producing dairy herds. J Dairy Sci 81: 132-139. https://doi.org/10.3168/jds.S0022-0302(98)75560-2
  3. Cozzi G, Ravarotto L, Gottardo F, Stefani AL, Contiero B, Moro L, Brscic M, Dalvit P. 2011. Short communication: reference values for blood parameters in Holstein dairy cows: effects of parity, stage of lactation, and season of production. J Dairy Sci 94: 3895-3901. https://doi.org/10.3168/jds.2010-3687
  4. Duffield T. 2000. Subclinical ketosis in lactating dairy cattle. Vet Clin North Am Food Anim Pract 16: 231-253, v. https://doi.org/10.1016/S0749-0720(15)30103-1
  5. Edmonson A, Lean I, Weaver L, Farver T, Webster G. 1989. A body condition scoring chart for Holstein dairy cows. Journal of dairy science 72: 68-78. https://doi.org/10.3168/jds.S0022-0302(89)79081-0
  6. Esposito G, Irons PC, Webb EC, Chapwanya A. 2014. Interactions between negative energy balance, metabolic diseases, uterine health and immune response in transition dairy cows. Anim Reprod Sci 144: 60-71. https://doi.org/10.1016/j.anireprosci.2013.11.007
  7. Friedrichs KR, Harr KE, Freeman KP, Szladovits B, Walton RM, Barnhart KF, Blanco-Chavez J, American Society for Veterinary Clinical P. 2012. ASVCP reference interval guidelines: determination of de novo reference intervals in veterinary species and other related topics. Vet Clin Pathol 41: 441-453. https://doi.org/10.1111/vcp.12006
  8. Goff JP. 2004. Macromineral disorders of the transition cow. Vet Clin North Am Food Anim Pract 20: 471-494, v. https://doi.org/10.1016/j.cvfa.2004.06.003
  9. Gonzalez FD, Muino R, Pereira V, Campos R, Benedito JL. 2011. Relationship among blood indicators of lipomobilization and hepatic function during early lactation in high-yielding dairy cows. J Vet Sci 12: 251-255. https://doi.org/10.4142/jvs.2011.12.3.251
  10. Horst RL, Goff JP, Reinhardt TA. 2005. Adapting to the transition between gestation and lactation: differences between rat, human and dairy cow. J Mammary Gland Biol Neoplasia 10: 141-156. https://doi.org/10.1007/s10911-005-5397-x
  11. Kayano M, Kida K. 2015. Identifying alterations in metabolic profiles of dairy cows over the past two decades in Japan using principal component analysis. J Dairy Sci 98: 8764-8774. https://doi.org/10.3168/jds.2015-9791
  12. Kida K. 2003. Relationships of metabolic profiles to milk production and feeding in dairy cows. J Vet Med Sci 65: 671-677. https://doi.org/10.1292/jvms.65.671
  13. Liang D, Wood CL, McQuerry KJ, Ray DL, Clark JD, Bewley JM. 2013. Influence of breed, milk production, season, and ambient temperature on dairy cow reticulorumen temperature. J Dairy Sci 96: 5072-5081. https://doi.org/10.3168/jds.2012-6537
  14. Mellado M, Antonio-Chirino E, Meza-Herrera C, Veliz FG, Arevalo JR, Mellado J, de Santiago A. 2011. Effect of lactation number, year, and season of initiation of lactation on milk yield of cows hormonally induced into lactation and treated with recombinant bovine somatotropin. J Dairy Sci 94: 4524-4530. https://doi.org/10.3168/jds.2011-4152
  15. Moretti P, Paltrinieri S, Trevisi E, Probo M, Ferrari A, Minuti A, Giordano A. 2017. Reference intervals for hematological and biochemical parameters, acute phase proteins and markers of oxidation in Holstein dairy cows around 3 and 30days after calving. Res Vet Sci 114: 322-331. https://doi.org/10.1016/j.rvsc.2017.06.012
  16. Puppel K, Kuczynska B. 2016. Metabolic profiles of cow's blood; a review. J Sci Food Agric 96: 4321-4328. https://doi.org/10.1002/jsfa.7779
  17. Quiroz-Rocha GF, LeBlanc SJ, Duffield TF, Wood D, Leslie KE, Jacobs RM. 2009. Reference limits for biochemical and hematological analytes of dairy cows one week before and one week after parturition. Can Vet J 50: 383-388.
  18. Reinhardt TA, Horst RL, Goff JP. 1988. Calcium, phosphorus, and magnesium homeostasis in ruminants. Vet Clin North Am Food Anim Pract 4: 331-350. https://doi.org/10.1016/S0749-0720(15)31052-5
  19. Roche JR, Lee JM, Macdonald KA, Berry DP. 2007. Relationships among body condition score, body weight, and milk production variables in pasture-based dairy cows. J Dairy Sci 90: 3802-3815. https://doi.org/10.3168/jds.2006-740
  20. Walters AH, Pryor AW, Bailey TL, Pearson RE, Gwazdauskas FC. 2002. Milk yield, energy balance, hormone, follicular and oocyte measures in early and mid-lactation Holstein cows. Theriogenology 57: 949-961. https://doi.org/10.1016/S0093-691X(01)00688-4