Journal of the Korean Society of Manufacturing Process Engineers (한국기계가공학회지)

The Korean Society of Manufacturing Process Engineers (한국기계가공학회)
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A Study on the Fabrication of 3D Scaffolds Using the Solid Freeform Method

임의 형상 제작 기법을 이용한 3차원 세포지지체 제작에 관한 연구

  • Choi, Do-Hyun (Department of Mechanical & Automotive Engineering, Inje University) ;
  • Kim, Hyun-Chul (Department of Electronic IT Mechanical & Automotive Engineering, Inje University)
  • 최도현 (인제대학교 기계자동차공학부) ;
  • 김현철 (고안전 차량 핵심기술연구소 인제대학교 전자IT기계자동차공학부)
  • Received : 2018.08.08
  • Accepted : 2018.09.27
  • Published : 2019.02.28
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Abstract

With the goal of tissue regeneration for organs damaged through an accident or a disease, research on tissue engineering has been conducted to produce 3-D scaffolds that can support the cells in the attachment and growth for the cell proliferation and differentiation. A scaffold requires a suitable pore size and porosity to increase the nutrient circulation or oxygen supply for the attachment and growth of cells. The existing production methods such as solvent-casting particulate leaching, phase separation, and fiber bonding have certain disadvantages. With these methods, it is difficult to obtain a free desired shape. In addition, certain pore sizes and interconnectivities among the pores may not be guaranteed. To solve these problems, this study has fabricated a scaffold with a 3-D shaped nose using Alginate, which is a natural polymer obtained through Fused Deposition Modeling (FDM), one of the CAD/CAM-based Solid Freeform Fabrication (SFF) methods.

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References

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