Journal of the Korean Medical Association (대한의사협회지)

Korean Medical Association (대한의사협회)
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Pathophysiology and new treatment of itch

가려움증의 병태생리 및 최신치료

  • Jung, Min Je (Department of Dermatology, Kangnam Sacred Heart Hospital, Hallym University College of Medicine) ;
  • Choi, Yong Won (Department of Dermatology, Kangnam Sacred Heart Hospital, Hallym University College of Medicine) ;
  • Chung, Bo Young (Department of Dermatology, Kangnam Sacred Heart Hospital, Hallym University College of Medicine) ;
  • Park, Chun Wook (Department of Dermatology, Kangnam Sacred Heart Hospital, Hallym University College of Medicine) ;
  • Kim, Hye One (Department of Dermatology, Kangnam Sacred Heart Hospital, Hallym University College of Medicine)
  • 정민재 (한림대학교 의과대학 강남성심병원 피부과학교실) ;
  • 최용원 (한림대학교 의과대학 강남성심병원 피부과학교실) ;
  • 정보영 (한림대학교 의과대학 강남성심병원 피부과학교실) ;
  • 박천욱 (한림대학교 의과대학 강남성심병원 피부과학교실) ;
  • 김혜원 (한림대학교 의과대학 강남성심병원 피부과학교실)
  • Received : 2018.10.15
  • Accepted : 2018.10.23
  • Published : 2018.11.20
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Abstract

Many of the patients visit the doctors because of itching sensation. Itching is an unpleasant sensation. In the epidermal keratinocytes, various neurotransmitters and receptors are related itching. The itch signal is mainly transmitted through the lateral spinal ganglion-derived nerve fibers extending to the lower epidermis. Many mediators such as histamine are involved in the itching pathway. It can be helpful in the treatment of patients having itching sensation with a lot of new therapies from the basic medication such as antihistamines. Also, many drugs are currently under study.

Keywords

References

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