Journal of Sensor Science and Technology (센서학회지)

The Korean Sensors Society (한국센서학회)
권호 표지
DOI QR코드

DOI QR Code

Fabrication and Improved Sensitivity with Surface Treatment of TiO2/GOD Mixture based Glucose Biosensor

TiO2/GOD 혼합물 기반의 글루코스 바이오 센서의 제작과 표면 처리를 통한 감도개선

  • Lee, Junyeop (School of Electronics Engineering, Kyungpook National University) ;
  • Jung, Dong Geon (School of Electronics Engineering, Kyungpook National University) ;
  • Lee, Jae Yong (School of Electronics Engineering, Kyungpook National University) ;
  • Kim, Jae Keon (Aircraft System Technology Group, Korea Institute of Industrial Technology) ;
  • Jung, Daewoong (Aircraft System Technology Group, Korea Institute of Industrial Technology) ;
  • Kong, Seong Ho (School of Electronics Engineering, Kyungpook National University)
  • 이준엽 (경북대학교 전자공학부) ;
  • 정동건 (경북대학교 전자공학부) ;
  • 이재용 (경북대학교 전자공학부) ;
  • 김재건 (한국생산기술연구원, 항공시스템기술그룹) ;
  • 정대웅 (한국생산기술연구원, 항공시스템기술그룹) ;
  • 공성호 (경북대학교 전자공학부)
  • Published : 2018.05.31
Download PDF
⟨ Previous Next ⟩

Abstract

In this paper, the $TiO_2$/glucose oxidase (GOD) mixture has synthesized through simple and low-cost fabrication methods. The physical properties of the mixture were proved using an FT-IR/NIR spectrometer, an X-Ray diffractometer, and a Raman spectrometer. GOD maintained its bioactivity during all fabrication process. The current characteristics of the glucose biosensor were proportional to the glucose concentration and effective surface area of square pyramid on a silicon substrate. The maximum current change was measured in a pH 7.0 buffer solution. The simple and low-cost fabrication process and surface treatment can be used widely in previous research for improvements in effective surface area.

Keywords

References

  1. J. Wang, "Electrochemical glucose biosensors", Chem. Rev., Vol.108(2), pp. 814-825, 2007. https://doi.org/10.1021/cr068123a
  2. A. Heller, "Electrical connection of enzyme redox centers to electrodes", J. Phys. Chem., Vol. 96(9), pp. 3578-3587, 1992.
  3. L Gorton, "Carbon paste electrodes modified with enzymes, tissues, and cells", Electroanalysis, Vol. 7(1), pp. 23-45, 1995. https://doi.org/10.1002/elan.1140070104
  4. P. N. Bartlett, P. Tebbutt, and R. G. Whitaker, Kinetic aspects of the use of modified electrodes and mediators in bioelectrochemistry, Pergamon Press, New York, pp. 1-101, 1991.
  5. M. Viticoli, A. Curulli, A. Cusma, S. Nunziante, L. Pandolfi, F. Valentini, and G. Padeletti, "Third-generation biosensors based on TiO2 nanostructured films", Mater. Sci. Eng. C, Vol. 26(5-7), pp. 947-951, 2006. https://doi.org/10.1016/j.msec.2005.09.080
  6. E. Topoglidis, A. E. G. Cass, G. Gilardi, S. Sadeghi, N. Beaumont, and J. R. Durrant, "Protein Adsorption on Nanocrystalline $TiO_2$ Films: An Immobilization Strategy for Bioanalytical Devices", Anal. Chem., Vol. 70(23), pp. 5111-5113, 1998. https://doi.org/10.1021/ac980764l