Journal of the Korean Society of Radiology (한국방사선학회논문지)

The Korean Society of Radiology (한국방사선학회)
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Analysis of Differences in Fractional Anisotropy of Diffusion Tensor Images of Basal Ganglia in the Brain Gray Matter according to Smoking

뇌 회백질 기저핵 부위의 흡연유무에 따른 확산텐서 비등방도 측정값 차이분석

  • Kwak, Jong Hyeok (Department of Radiology, Pusan National University hospital of Yang San) ;
  • Jeong, Jae Beom (Graduate School of Health Sciences, Busan Catholic University) ;
  • Son, Bong Kyeong (Department of Radiology, Pusan National University hospital of Yang San) ;
  • Sung, Soon Ki (Gamma knife center, Pusan National University Hospital of Yang San) ;
  • Kim, Seong Jin (Gamma knife center, Pusan National University Hospital of Yang San) ;
  • Kang, Dong Won (Department of Radiology, Pusan National University hospital of Yang San) ;
  • Park, Chan Hyeok (Department of Radiology, Pusan National University hospital of Yang San) ;
  • Im, Hyeon Wha (Department of Nursing, Choonhae College of Health Sciences) ;
  • Lee, Yu Hui (Department of Dental Hygiene, Choonhae College of Health Sciences) ;
  • Lee, Bong Sang (Graduate School of Health Sciences, Inje university) ;
  • Kim, Dong hyeon (Graduate School of Health Sciences, Busan Catholic University)
  • 곽종혁 (양산부산대학교병원 영상의학과) ;
  • 정재범 (부산가톨릭대학교 보건과학대학원) ;
  • 손봉경 (양산부산대학교병원 영상의학과) ;
  • 성순기 (양산부산대학교병원 감마나이프센터) ;
  • 김성진 (양산부산대학교병원 감마나이프센터) ;
  • 강동원 (양산부산대학교병원 영상의학과) ;
  • 박찬혁 (양산부산대학교병원 영상의학과) ;
  • 임현화 (춘해보건대학교 간호과) ;
  • 이유희 (춘해보건대학교 치위생과) ;
  • 이상봉 (인제대학교 일반대학원 보건학과) ;
  • 김동현 (부산가톨릭대학교 보건과학대학원)
  • Received : 2018.02.13
  • Accepted : 2018.04.30
  • Published : 2018.04.30
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Abstract

The fractional anisotropy value of the basal ganglia fibers in the brain gray matter region was analyzed by Tract-Based Spatial Statics(TBSS) method after acquiring the diffusion tensor image to identify the presence or absence of brain white matter damage to smoking in male. As a result of measurement analysis, the fractional anisotropy measurement value was lower in smokers than non-smokers in all areas, and the FA value was statistically significant. smoking significantly affects all the anatomic micro structural changes in the brain gray matter and damages the nerve fiber tract. As a result, it can affects functional abnormalities related to the minute changes of the brain due to smoking.

흡연 유무의 남성을 대상으로 뇌 회백질의 손상 유무를 파악 할 수 있는 확산텐서영상을 검사하여 영상을 획득 한 후 Tract-Based Spatial Statics(TBSS)방법으로 뇌 회백질 부위의 기저핵 신경섬유로의 비등방도 FA(fractional anisotropy)값을 측정 분석한 결과 모든 영역에서 흡연자가 비흡연자보다 비등방성 측정값이 낮게 관찰되었으며 FA값은 통계적으로 유의하였다. 본 연구의 측정한 FA결과 값으로 추측하자면 즉, 흡연이 뇌 회백질 기저핵의 모든 해부학적 미세 구조성 변화에 크게 영향을 미치며 신경 섬유로를 손상시키고 이와 관련된 기능적 이상에 영향을 준다고 할 수 있다.

Keywords

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