Korean Journal of Veterinary Research (대한수의학회지)

The Korean Society of Veterinary Science (대한수의학회)
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Detection and characterization of avian hepatitis E virus from broiler breeders and layers in Korea

육용종계와 산란계에서 avian hepatitis E virus의 검출 및 특성 규명

  • Moon, Hyun-Woo (Laboratory of Veterinary Microbiology, College of Veterinary Medicine and Institute of Veterinary Science, Kangwon National University) ;
  • Sung, Haan Woo (Laboratory of Veterinary Microbiology, College of Veterinary Medicine and Institute of Veterinary Science, Kangwon National University) ;
  • Kwon, Hyuk Moo (Laboratory of Veterinary Microbiology, College of Veterinary Medicine and Institute of Veterinary Science, Kangwon National University)
  • 문현우 (강원대학교 수의과대학.동물의학종합연구소) ;
  • 성환우 (강원대학교 수의과대학.동물의학종합연구소) ;
  • 권혁무 (강원대학교 수의과대학.동물의학종합연구소)
  • Received : 2017.12.01
  • Accepted : 2018.02.08
  • Published : 2018.03.31
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Abstract

The helicase genes and hypervariable regions (HVRs) of three avian hepatitis E viruses (HEVs) detected at three different farms were sequenced and characterized. Two isolates (DW-L and GI-B2) were classified as genotype 2 and one isolate (GR-B) was classified as genotype 1. A phylogenetic tree, based on the helicase gene and HVR nucleotide sequences, revealed the newly detected viruses and other avian HEVs were classified similarly. Unlike previously reported avian HEVs, the DW-L isolate detected in broiler breeders with characteristic lesions of avian HEV had no proline-rich motif in its HVR, suggesting that the proline-rich motif is non-essential for viral replication and infection.

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References

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