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http://dx.doi.org/10.14405/kjvr.2018.58.1.45

Detection and characterization of avian hepatitis E virus from broiler breeders and layers in Korea  

Moon, Hyun-Woo (Laboratory of Veterinary Microbiology, College of Veterinary Medicine and Institute of Veterinary Science, Kangwon National University)
Sung, Haan Woo (Laboratory of Veterinary Microbiology, College of Veterinary Medicine and Institute of Veterinary Science, Kangwon National University)
Kwon, Hyuk Moo (Laboratory of Veterinary Microbiology, College of Veterinary Medicine and Institute of Veterinary Science, Kangwon National University)
Publication Information
Korean Journal of Veterinary Research / v.58, no.1, 2018 , pp. 45-49 More about this Journal
Abstract
The helicase genes and hypervariable regions (HVRs) of three avian hepatitis E viruses (HEVs) detected at three different farms were sequenced and characterized. Two isolates (DW-L and GI-B2) were classified as genotype 2 and one isolate (GR-B) was classified as genotype 1. A phylogenetic tree, based on the helicase gene and HVR nucleotide sequences, revealed the newly detected viruses and other avian HEVs were classified similarly. Unlike previously reported avian HEVs, the DW-L isolate detected in broiler breeders with characteristic lesions of avian HEV had no proline-rich motif in its HVR, suggesting that the proline-rich motif is non-essential for viral replication and infection.
Keywords
avian hepatitis E virus; helicase gene; hypervariable region; sequences;
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