Journal of the Korea Academia-Industrial cooperation Society (한국산학기술학회논문지)

The Korea Academia-Industrial cooperation Society (한국산학기술학회)
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Effects of Oral Vitamins on the Elderly with Mild Cognitive Impairment

비타민 보충제 영양강화요법이 경도인지기능장애 노인에게 미치는 효과

  • 이혜경 (수원여자대학교 간호학과)
  • Received : 2017.06.15
  • Accepted : 2017.08.17
  • Published : 2017.08.31
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Abstract

As the elderly population increases, the prevalence of various geriatric chronic diseases and dementia diseases is also rapidly increasing; accordingly, dementia is becoming a major concern of our society. In this study, 48 elderly patients with mild cognitive impairment located in K district were selected from a group of experimental groups in one building and a control group in one building and evaluated for blood homocysteine levels and cognitive function changes after 4,8, and 12 weeks of taking vitamin supplements. The Chi-squared test, Fisher's Exact test, independent t-test, repeated measures ANOVA, contrast test, repeated measures ANCOVA, and Wilks' lambda test were utilized to analyze the data. The results revealed that the cognitive function of the experimental group was significantly higher than that of the control group at 12 weeks (p<0.05), and so, the experimental group higher than that of the control group (p<0.01), the effect of taking vitamins was significantly increased, indicating that homocysteine was decreased relative to the control group. Therefore, vitamin supplements may prevent decreases in cognitive functions and dementia among elderly patients with mild cognitive impairment.

고령인구가 증가하면서 각종 노인성 만성질환 및 치매질환의 유병률 또한 빠르게 증가하고 있으며, 치매는 우리사회의 큰 관심 질환으로 대두되고 있다. 본 연구에서는 노인복지시설에서 거주하고 있는 인지장애 노인을 대상으로 비타민 보충제의 영양 강화요법이 경도인지기능 노인에게 미치는 효과를 보고자 하였다. 자료는 K지역에 위치한 노인복지시설 2개의 다른 건물에 입소한 노인 48명을 대상으로 각각 다른 건물에서 하나의 건물에서는 실험군 집단을 하나의 건물에서는 대조군 집단을 선정하였으며, 4,8,12주에 걸쳐 비타민 보충제를 복용한 후 호모시스테인 혈중농도와 인지기능을 평가하였다. 표집방법은 자료수집의 용이함을 고려하여 임의 표집방법을 이용분석을 위해 Chi-Square test, Fisher's Exact test와 independent t-test, Repeated Measure ANOVA, Contrast test, Repeated Measure ANCOVA, Wilks' lambda test를 실시하였으며, 인지기능 향상 효과에 대한 Contrast test를 실시한 결과, 12주차(p<.001) 에서 유의한 효과가 있는 것으로 나타났다. 경구 비타민제를 복용한 실험군의 인지기능 12주에서 대조군보다 각 시기별 차이를 분석한 결과 12주차(p<.05)에 실험군의 인지기능이 대조군보다 높게 나타났고, 호모시스테인 효과에 대한 12주(p<.01)에서 비타민제 복용이 효과가 유의하게 발생하여 대조군보다 호모시스테인이 감소한 것으로 나타났다. 결과적으로 경구비타민을 복용한 노인에게서 인지기능이 증가하였고, 호모시스테인 혈중농도가 주별 지속적으로 감소하였다. 이러한 결과는 치매로 갈 수 있는 경도인지장애 대상자들에게 비타민 보충제 복용은 상대적으로 비용이 저렴하고, 복용이 간편하여 추후 인지기능 저하 및 치매발생을 예방할 것으로 기대된다.

Keywords

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