The Experimental Study of Glycyrrhiza uralensis on Wound Healing by Antioxidant Effect

감초 추출물의 항산화 효과에 의한 상처 치료 가능성 연구

  • Lee, Yun Kyung (Dept. of Oriental Internal Medicine, Graduate school of Korean Medicine, Daejeon University) ;
  • Roh, Seok Sun (Dept. of Oriental Internal Medicine, Graduate school of Korean Medicine, Daejeon University)
  • Received : 2016.07.08
  • Accepted : 2016.07.28
  • Published : 2016.08.20

Abstract

Objectives : The purpose of this study is to evaluate the wound healing potential of Glycyrrhiza uralensis extract. Methods : Free radical scavenging activity tests for DPPH, peroxynitrite (ONOO) and hydroxyl radical (${\cdot}OH$) and total phenolic contents of Glycyrrhiza uralensis extract were conducted. Tube formation assay was performed using human umbilical vein endothelial cells (HUVECs). Results : The results showed that Glycyrrhiza uralensis extract exerted inhibitory effects on ONOO and ${\cdot}OH$. Tube formation in HUVEC was increase in a dose dependent manner. Conclusions : These results show the potential to promote the wound healing process by Glycyrrhiza uralensis extract.

Keywords

References

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